Protein Alignment Vha100-3 and Vha100-1

DIOPT Version :10

• Sequence 1: NP_725837.1
• Gene: Vha100-3 / 246543
• FlyBaseID: FBgn0028669
• Length: 904
• Species: Drosophila melanogaster
• Sequence 2: NP_651672.1
• Gene: Vha100-1 / 43442
• FlyBaseID: FBgn0028671
• Length: 855
• Species: Drosophila melanogaster
• Alignment Length: 928
• Identity: 342/928 - (36%)
• Similarity: 484/928 - (52%)
• Gaps: 131/928 - (14%)

  Fly    13 SFFRSEDMDLCQLLLHTENAFDCLIEVGHHGAVQFNNVYDEDRLLNNLYSKKVTQCYELLRIVDS 77
            |.||||:|.||||.|.:|.|:.|:.|:|..|.|||.::..:.......:..:|.:|.|:.|.:..
  Fly     3 SLFRSEEMALCQLFLQSEAAYACVSELGELGLVQFRDLNPDVNAFQRKFVNEVRRCDEMERKLRY 67

  Fly    78 LHTYIVQ-----LHVNEIFYPDVDRENRLKEKDLAKYSDSLKRIHVEASAVTEHYYRLDSRRNRM 137
            |...|.:     |...|.......||....|....|..:.|:.::..|.|:..::..|..
  Fly    68 LEKEIKKDGIPMLDTGESPEAPQPREMIDLEATFEKLENELREVNQNAEALKRNFLELTE----- 127

  Fly   138 MEHSFALNKANKYMVSDMGSELLYSESTVIGLVQDATTTSGAYPA-------------------- 182
            ::|  .|.|          :::.:.||     |.....:||||.:
  Fly   128 LKH--ILRK----------TQVFFDES-----VPTVYKSSGAYSSSKYRRYPQMADNQNEDEQAQ 175

  Fly   183 ----------------HLNYMIGCIRADKFYSFELLLYRLCSFNLIIRFSEMPSPVYEYHYGYKP 231
                            .|.::.|.|..::..:||.:|:|.|..|:.:|.:.:.:|:.:...|
  Fly   176 LLGEEGVRASQPGQNLKLGFVAGVILRERLPAFERMLWRACRGNVFLRQAMIETPLEDPTNG--- 237

  Fly   232 ERVRKFAILMMASSTMIWPKVLKICAHYHVNIYDCPSSASQREDKVKELSQEIVNVEKVLKEAEL 296
            ::|.|...::......:..:|.|||..:...:|.||.:.:.|.:....:...|.::..||.:.:.
  Fly   238 DQVHKSVFIIFFQGDQLKTRVKKICEGFRATLYPCPEAPADRREMAMGVMTRIEDLNTVLGQTQD 302

  Fly   297 MRRQILEVAGRDLFIIRVNLRKALKVYDLMNRLRLVGGVEV-PRYLLAEVYIPSSDVPEVEVILR 360
            .|.::|..|.::|....|.:||...:|..:|...|    :| .:.|:||.::|..|:..:::.||
  Fly   303 HRHRVLVAAAKNLKNWFVKVRKIKAIYHTLNLFNL----DVTQKCLIAECWVPLLDIETIQLALR 363

  Fly   361 NASRISGGADNIDSSDEDEMNDMKTMPNTTPYPIEADFQPLEDMSAGAILLKKNRLVNHMPPTYF 425
            ..:..||      ||....:|.|:|..|                                ||||.
  Fly   364 RGTERSG------SSVPPILNRMQTFEN--------------------------------PPTYN 390

  Fly   426 RLNKFTRGFQNLIDAYGMADYKELNPAPYTIITFPFLFAVMFGDLGHGILLILFSSLMIWKHREI 490
            |.||||:.||.||||||:|.|:|:||||||||||||||||||||||||.::.||...||.|
  Fly   391 RTNKFTKAFQALIDAYGVASYREMNPAPYTIITFPFLFAVMFGDLGHGAIMALFGLWMIRK---- 451

  Fly   491 EKYQINATSENEILNILYAGRYIILLMGVFSVYMGLVYNIVMAKGFNLFGSSWSCRYNETTVYDP 555
            ||......::|||.||.:.|||||.||||||:|.||:||.:.:|..|:|||.|...||::||.:.
  Fly   452 EKGLAAQKTDNEIWNIFFGGRYIIFLMGVFSMYTGLIYNDIFSKSLNIFGSHWHLSYNKSTVMEN 516

  Fly   556 AFHVTLDSSHPHFYSGHPYPLGMDPVWAVCGQDSITTTNSLKMKMAIVLGISQMMFGLGLAAANC 620
            .|   |..|....|.|.|||.||||:|.|.|.:.|...|:.|||::|:.|:..|:||:.::..|.
  Fly   517 KF---LQLSPKGDYEGAPYPFGMDPIWQVAGANKIIFHNAYKMKISIIFGVIHMIFGVVMSWHNH 578

  Fly   621 VLMNRKADLILVVIPQMIFMLCLFGYLVFLIFYKWMSYGGHKPAPYNAACAPSVLITFINMMLMK 685
            .....:..|:...|||::|:|.||.|:|.|:|.||:.:......||:.|||||:|||||:|:|..
  Fly   579 TYFRNRISLLYEFIPQLVFLLLLFFYMVLLMFIKWIKFAATNDKPYSEACAPSILITFIDMVLFN 643

  Fly   686 -KEDPVENCLDYMYPNERMIEFALVGIAFCTIPILLAGKPIYLMRRRRKMQQERERDFKRMRRQT 749
             .:.|.|||..||:..:..|:...|.:|...||::|..||:.:|:.|           |:...|.
  Fly   644 TPKPPPENCETYMFMGQHFIQVLFVLVAVGCIPVMLLAKPLLIMQAR-----------KQANVQP 697

  Fly   750 IAEMRSTMRYTDDDNSETSRQKSVDNEEEHEMSEIWIHSGIHTIETVLGSVSHTASYLRLWALSL 814
            ||...|........|| .|......:|||.|:|||:||..|||||.|||||||||||||||||||
  Fly   698 IAGATSDAEAGGVSNS-GSHGGGGGHEEEEELSEIFIHQSIHTIEYVLGSVSHTASYLRLWALSL 761

  Fly   815 AHDQLSDVLWHMVLTKGFANTLPLYYGVPVLMATFFAWAILTVAILVMMEGLSAFLHTLRLHWVE 879
            ||.||::|||.|||:.|.....|:  |..||...|..||||||.|||:|||||||||||||||||
  Fly   762 AHAQLAEVLWTMVLSIGLKQEGPV--GGIVLTCVFAFWAILTVGILVLMEGLSAFLHTLRLHWVE 824

  Fly   880 FQSKFFGGAGESFKAFNF 897
            |||||:.|.|.:|:.|:|
  Fly   825 FQSKFYKGQGYAFQPFSF 842

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vha100-3	NP_725837.1	V_ATPase_I	38..897	CDD:460232	327/901 (36%)
Vha100-1	NP_651672.1	V_ATPase_I	27..842	CDD:460232	327/902 (36%)