Protein Alignment Vha100-3 and Vha100-2

DIOPT Version :10

• Sequence 1: NP_725837.1
• Gene: Vha100-3 / 246543
• FlyBaseID: FBgn0028669
• Length: 904
• Species: Drosophila melanogaster
• Sequence 2: NP_650722.1
• Gene: Vha100-2 / 42216
• FlyBaseID: FBgn0028670
• Length: 834
• Species: Drosophila melanogaster
• Alignment Length: 895
• Identity: 320/895 - (35%)
• Similarity: 492/895 - (54%)
• Gaps: 87/895 - (9%)

  Fly    15 FRSEDMDLCQLLLHTENAFDCLIEVGHHGAVQFNNVYDEDRLLNNLYSKKVTQCYELLRIVDSLH 79
            ||||:|.|||:.:..|.|:..:.|:|..|.|||.::..........:..:|.:|.||.|.:..:.
  Fly     5 FRSEEMALCQMFIQPEAAYTSVSELGETGCVQFRDLNVNVNAFQRKFVTEVRRCDELERKIRYIE 69

  Fly    80 TYIVQLHVNEIFYPDVDRENRLKEKDLAKYSDSLKRIHVEASAVTEHYYRLDSRRN--RMMEHSF 142
            |   ::..:.|..||:       :.|:.:..:..:.|.:||.........::..:|  .|..:..
  Fly    70 T---EIKKDGIVLPDI-------QDDIPRAPNPREIIDLEAHLEKTESEMIELAQNEVNMKSNYL 124

  Fly   143 ALNKANKYMVSDMGSELLYSESTVIGLVQDATTTSGA-------YPAHLNYMIGCIRADKFYSFE 200
            .|.:..|.:.:..|   .:|:..|:.|  |::..:|.       :...|.::.|.|..::.::||
  Fly   125 ELTELRKVLENTQG---FFSDQEVLNL--DSSNRAGGDNDAAAQHRGRLGFVAGVINRERVFAFE 184

  Fly   201 LLLYRLCSFNLIIRFSEMPSPVYEYHYGYKPERVRKFAILMMASSTMIWPKVLKICAHYHVNIYD 265
            .:|:|:...|:.::.|::..|:.:...|:.   :.|...:.......:..::.|:|..:|.::|.
  Fly   185 RMLWRISRGNVFLKRSDLDEPLNDPATGHP---IYKTVFVAFFQGEQLKNRIKKVCTGFHASLYP 246

  Fly   266 CPSSASQREDKVKELSQEIVNVEKVLKEAELMRRQILEVAGRDLFIIRVNLRKALKVYDLMNRLR 330
            ||||.::||:.|:.:...:.:::.||.:.|..|.::|....::|....:.::|...:|..:|...
  Fly   247 CPSSHNEREEMVRNVRTRLEDLKLVLSQTEDHRSRVLATVSKNLPSWSIMVKKMKAIYHTLNLFN 311

  Fly   331 LVGGVEV-PRYLLAEVYIPSSDVPEVEVILRNASRISGGADNIDSSDEDEMNDMKTMPNTTPYPI 394
            :    :| .:.|:.|.::|::|:|.|:..|.:.|...|                .|:|:
  Fly   312 M----DVTKKCLIGECWVPTNDLPVVQKALSDGSAAVG----------------STIPS------ 350

  Fly   395 EADFQPLEDMSAGAILLKKNRLVNHMPPTYFRLNKFTRGFQNLIDAYGMADYKELNPAPYTIITF 459
               |..:.|             .|..|||:.|.|||||||||||||||:|.|:|.|||.||.|||
  Fly   351 ---FLNVID-------------TNEQPPTFNRTNKFTRGFQNLIDAYGVASYRECNPALYTCITF 399

  Fly   460 PFLFAVMFGDLGHGILLILFSSLMIWKHREIEKYQINATSENEILNILYAGRYIILLMGVFSVYM 524
            ||||||||||||||::|:||.:.|:...|::.:.:    :..||.||.:.|||||||||:|::|.
  Fly   400 PFLFAVMFGDLGHGLILVLFGAWMVLCERKLARIR----NGGEIWNIFFGGRYIILLMGLFAMYT 460

  Fly   525 GLVYNIVMAKGFNLFGSSWSCRYNETTVY-DPAFHVTLDSSHPHFYSGHPYPLGMDPVWAVCGQD 588
            |||||.|.:|..|||||.|...||.|||. :|...:..:||     :...||.||||||.: ..:
  Fly   461 GLVYNDVFSKSMNLFGSRWFNNYNTTTVLTNPNLQLPPNSS-----AVGVYPFGMDPVWQL-ADN 519

  Fly   589 SITTTNSLKMKMAIVLGISQMMFGLGLAAANCVLMNRKADLILVVIPQMIFMLCLFGYLVFLIFY 653
            .|...||.|||::|:.|:..|:||:.::..|.....|.|.:.|..:||::|:|.||||:||::|:
  Fly   520 KIIFLNSFKMKLSIIFGVLHMVFGVCMSVVNFTHFKRYASIFLEFVPQILFLLLLFGYMVFMMFF 584

  Fly   654 KWMSYGGHKP-APYNAACAPSVLITFINMMLMKKEDPVENCLDYMYPNERMIEFALVGIAFCTIP 717
            ||.||..... .|....|||||||.||||||.|..:|.:.|.::|:.::..::.|.|.||.|.||
  Fly   585 KWFSYNARTSFQPETPGCAPSVLIMFINMMLFKNTEPPKGCNEFMFESQPQLQKAFVLIALCCIP 649

  Fly   718 ILLAGKPIYLMRRRRKMQQERERDFKRMRRQTIAEMRSTMRYTDDDNSETSRQKSVDNEEEHEMS 782
            .:|.|||:|: :..||.:.....:.:......:||..:.:......|.|.:  ......::..||
  Fly   650 WMLLGKPLYI-KFTRKNKAHANHNGQLTGNIELAEGETPLPTGFSGNEENA--GGAHGHDDEPMS 711

  Fly   783 EIWIHSGIHTIETVLGSVSHTASYLRLWALSLAHDQLSDVLWHMVLTKGFANTLPLYYGVPVLMA 847
            ||:||..|||||.||.::||||||||||||||||.|||:|||.|||:.|.  .:....|...|..
  Fly   712 EIYIHQAIHTIEYVLSTISHTASYLRLWALSLAHAQLSEVLWQMVLSLGL--KMSGVGGAIGLFI 774

  Fly   848 TFFAWAILTVAILVMMEGLSAFLHTLRLHWVEFQSKFFGGAGESFKAFNF 897
            .|.||.:.|:||||:||||||||||||||||||.|||:.|.|.:|:.|:|
  Fly   775 IFGAWCLFTLAILVLMEGLSAFLHTLRLHWVEFMSKFYEGMGYAFQPFSF 824

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vha100-3	NP_725837.1	V_ATPase_I	38..897	CDD:460232	309/870 (36%)
Vha100-2	NP_650722.1	V_ATPase_I	27..824	CDD:460232	309/871 (35%)