Protein Alignment Vha100-3 and Vha100-4

DIOPT Version :10

• Sequence 1: NP_725837.1
• Gene: Vha100-3 / 246543
• FlyBaseID: FBgn0028669
• Length: 904
• Species: Drosophila melanogaster
• Sequence 2: NP_650720.1
• Gene: Vha100-4 / 42214
• FlyBaseID: FBgn0038613
• Length: 844
• Species: Drosophila melanogaster
• Alignment Length: 911
• Identity: 308/911 - (33%)
• Similarity: 477/911 - (52%)
• Gaps: 117/911 - (12%)

  Fly    13 SFFRSEDMDLCQLLLHTENAFDCLIEVGHHGAVQFNNVYDEDRLLNNLYSKKVTQCYELLR---- 73
            |.||||.|.|.|:.|..|.|:|.:..:|..|.|||.::..:.......:..:|.:|.||.|
  Fly    15 SIFRSEVMSLVQMYLQPEAAYDTIAALGEVGCVQFRDLNAKINAQQRKFIGEVRRCDELERRIRY 79

  Fly    74 -----------IVDSLHTYIVQLHVNEIFYPDVDRENRLKEK-----DLAKYSDSLKRIHVEASA 122
                       ::|.:..:.......||    :|.|..|::.     :||..:.:|:..::|.|.
  Fly    80 VTAELNKEGHKVLDLMDDFPPAPQPREI----IDLELHLEKTETEILELAANNVNLQTSYLELSE 140

  Fly   123 VTEHYYRLDSRRNRMMEHSFALNKANKYMVSDMGSELLYSESTVIGLVQDATTTSGAYPAHLNYM 187
            :.:...|.|...:....|:|.|||                    :|..:|...::|    ||.::
  Fly   141 MIQVLERTDQFFSDQESHNFDLNK--------------------MGTHRDPEKSNG----HLGFV 181

  Fly   188 IGCIRADKFYSFELLLYRLCSFNLIIRFSEMPSPVYEYHYGYKPERVRKFAILMMASSTMIWPKV 252
            .|.|..::.|:||.:|:|:...|:.:|..::...:.:...|   ..:.|...::......:..::
  Fly   182 AGVISREREYAFERMLWRISRGNVFVRRCDVDVALTDPKTG---NVLHKSVFVVFFQGDQLQARI 243

  Fly   253 LKICAHYHVNIYDCPSSASQREDKVKELSQEIVNVEKVLKEAELMRRQILEVAGRDLFIIRVNLR 317
            .|:|..:|.::|.||||.|:|::.||.:...:.:::.::.:....|..:|:.|.:.|......::
  Fly   244 RKVCTGFHAHMYPCPSSHSERQEMVKNVRTRLEDLQVIINQTSDHRTCVLQAALKQLPTWSAMVK 308

  Fly   318 KALKVYDLMNRLRLVGGVEVPRYLLAEVYIPSSDVPEVEVILRNASRISGGADNIDSSDEDEMND 382
            |...:|..:|...:..|   .:.|:.|.::|..::..|||.|      :.|:.::.|:....:|.
  Fly   309 KMKGIYHTLNLFNVDLG---SKCLIGEGWVPKRELELVEVAL------AAGSASVGSTVPSFINV 364

  Fly   383 MKTMPNTTPYPIEADFQPLEDMSAGAILLKKNRLVNHMPPTYFRLNKFTRGFQNLIDAYGMADYK 447
            :.|                          ||.      |||:||.|||||||||||||||:|.|:
  Fly   365 LDT--------------------------KKE------PPTHFRTNKFTRGFQNLIDAYGIAGYR 397

  Fly   448 ELNPAPYTIITFPFLFAVMFGDLGHGILLILFSSLMIWKHREIEKYQINATSENEILNILYAGRY 512
            |:||..||.|||||||||||||:|||.:|.|....|:     |::.:::.....||.||.:||||
  Fly   398 EVNPGLYTCITFPFLFAVMFGDMGHGTILFLLGLWMV-----IDEKRLSKKRGGEIWNIFFAGRY 457

  Fly   513 IILLMGVFSVYMGLVYNIVMAKGFNLFGSSWSCRYNETTVY-DPAFHVTLDSSHPHFYSGHPYPL 576
            ||:|||:|::|.|..||.:.:|..|:||:.|...||.|||. :|...:     :|...:...||:
  Fly   458 IIMLMGLFAMYTGFHYNDIFSKSINVFGTRWVNVYNRTTVLTNPTLQL-----NPSVATRGVYPM 517

  Fly   577 GMDPVWAVCGQDSITTTNSLKMKMAIVLGISQMMFGLGLAAANCVLMNRKADLILVVIPQMIFML 641
            |:||:|. ...:.|...|:.|||::|:.|:..|:||:.::..|.|...:.|.:||..:||::|:|
  Fly   518 GIDPIWQ-SASNKIIFLNTYKMKLSIIFGVLHMVFGVCMSVENFVFFKKYAYIILQFVPQVLFLL 581

  Fly   642 CLFGYLVFLIFYKWMSYGGHKPAPYNA-ACAPSVLITFINMMLMKKEDPVENCLDYMYPNERMIE 705
            .:|||:.|::||||:.|........:. .|||||||.||:|:|.|.|..:..|...|:|.::.:|
  Fly   582 LMFGYMCFMMFYKWVKYSPTTDVEADTPGCAPSVLIMFIDMVLFKTETALPGCDVNMFPIQKNLE 646

  Fly   706 FALVGIAFCTIPILLAGKPIYLMRRRRKMQ----QERERDFKRMRRQTIAEMRSTMRYTDDDNSE 766
            ...:.:|...||.:|.|||:|:..:||...    :|.:...:::...|..|:..|      :.:|
  Fly   647 MIFLVVALLCIPWILLGKPLYIKYQRRNRPAGPVEEVDEIVEKIEVTTGKEIIIT------EVAE 705

  Fly   767 TSRQKSVDNEEEHEMSEIWIHSGIHTIETVLGSVSHTASYLRLWALSLAHDQLSDVLWHMVLTKG 831
            .........|::..|||||||..|||||.:|.::||||||||||||||||.|||:|||.|||..|
  Fly   706 AHESGGHSEEDDEPMSEIWIHQAIHTIEYILSTISHTASYLRLWALSLAHAQLSEVLWTMVLAMG 770

  Fly   832 FANTLPLYYGVPVLMATFFAWAILTVAILVMMEGLSAFLHTLRLHWVEFQSKFFGGAGESFKAFN 896
            .  .:..|.|...|...|..|...|:||:||||||||||||||||||||.|||:.|.|..|..|:
  Fly   771 L--QMNGYVGAIGLFFIFAVWEFFTIAIMVMMEGLSAFLHTLRLHWVEFMSKFYVGNGYPFTPFS 833

  Fly   897 F 897
            |
  Fly   834 F 834

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vha100-3	NP_725837.1	V_ATPase_I	38..897	CDD:460232	295/884 (33%)
Vha100-4	NP_650720.1	V_ATPase_I	39..834	CDD:460232	295/885 (33%)