Protein Alignment Vha100-3 and LOC1281585

DIOPT Version :10

• Sequence 1: NP_725837.1
• Gene: Vha100-3 / 246543
• FlyBaseID: FBgn0028669
• Length: 904
• Species: Drosophila melanogaster
• Sequence 2: XP_321519.1
• Gene: LOC1281585 / 1281585
• VectorBaseID: AGAMI1_004174
• Length: 808
• Species: Anopheles gambiae
• Alignment Length: 908
• Identity: 310/908 - (34%)
• Similarity: 492/908 - (54%)
• Gaps: 135/908 - (14%)

  Fly    13 SFFRSEDMDLCQLLLHTENAFDCLIEVGHHGAVQFNNVYDEDRLLNNLYSKKVTQCYELLRIVDS 77
            :.||||:|.:.|||:..|.|:..:.|:|..|..||.::..:..:....|:.::.:|.|:.|.:..
Mosquito     3 AMFRSEEMSMVQLLIQPEAAYQSVAELGELGIAQFRDLNTDINMFQRKYTSEIRRCEEMERKIGY 67

  Fly    78 LHTYIVQLHVNEIFYPDVDRENRLKEKDLAKYSDSLKRIHVEAS-AVTEH-YYRLDSRRNRMMEH 140
            :...||:   :.:..||:       .:.:.:..:|.:.|.:||. ..||: ...|....|.::::
Mosquito    68 IRREIVK---DSVAIPDM-------PEVIPRTPNSREIIDLEAQLEKTENEIVELSENNNALLQN 122

  Fly   141 SFALNKANKYMVSDMGSELLYSESTVIGLVQDATTTSG-----AYPAHLNYMIGCIRADKFYSFE 200
            ...|.:. |:::..  :::.:|:.:   .||:...|.|     ..|  |.::.|.|..::...||
Mosquito   123 FMELTEL-KHVLEK--TQVFFSDKS---NVQNLEATGGEAANDGKP--LGFVAGVISRERIIGFE 179

  Fly   201 LLLYRLCSFNLIIRFSEMPSPVYEYHYGYKPERVRKFAILMMASSTMIWPKVLKICAHYHVNIYD 265
            .:|:|:...|:.:|.:.:...:.:...|   :.|.|...:.......:..:|.|:||.||.::|.
Mosquito   180 RMLWRVSRGNIFLRQATLEESLVDPKTG---DSVHKIVFVAFFQGEQLKARVKKVCAGYHASLYP 241

  Fly   266 CPSSASQREDKVKELSQEIVNVEKVLKEAELMRRQILEVAGRDLFIIRVNLRKALKVYDLMNRLR 330
            ||:..::||:.::.:...|.:::.||.:.:..|:::|....:::....:.::|...:|..:|..
Mosquito   242 CPNEYNEREEMLRGVRTRIEDLKMVLGQTQDQRQRVLLNVAKEVPNWEIIVKKVKAIYHTLNMF- 305

  Fly   331 LVGGVEV-PRYLLAEVYIPSSDVPEVEVILRNASRISGGAD----NIDSSDEDEMNDMKTMPNTT 390
               .|:| .:.|..|.::|::.:.:|:..|.|.|...|.|.    ||.::|||
Mosquito   306 ---NVDVSKKCLFGEAWVPTAGLQDVKTALVNGSAAVGSAVPSFLNIIATDED------------ 355

  Fly   391 PYPIEADFQPLEDMSAGAILLKKNRLVNHMPPTYFRLNKFTRGFQNLIDAYGMADYKELNPAPYT 455
                                          ||||.:.|||||||||||::||:|.|:|.|||.||
Mosquito   356 ------------------------------PPTYNKTNKFTRGFQNLIESYGIATYREANPALYT 390

  Fly   456 IITFPFLFAVMFGDLGHGILLILFSSLMIWKHREIEKYQINATSENEILNILYAGRYIILLMGVF 520
            |||||||||:||||||||::|.|....|:...:.::|      ::.||..:.:.|||||||||:|
Mosquito   391 IITFPFLFAIMFGDLGHGLILFLLGMWMVLWEKTLDK------NKEEIWQLFFGGRYIILLMGIF 449

  Fly   521 SVYMGLVYNIVMAKGFNLFGSSWSCRYNETTVY---DPAFHVTLDSSHPHFYSGHPYPLGMDPVW 582
            |:|.|.|||.|.:||.|:|||:||..||.:||.   :...:.|.|      ||...|..|:||:|
Mosquito   450 SMYTGFVYNDVFSKGMNIFGSAWSVNYNTSTVMTNKELQLNPTTD------YSETVYWYGLDPLW 508

  Fly   583 AVCGQDSITTTNSLKMKMAIVLGISQMMFGLGLAAANCVLMNRKADLILVVIPQMIFMLCLFGYL 647
             :...:.|...||.|||::|:.|:..|:||:.::..|....||:.:::|..||||:|::.||.|:
Mosquito   509 -MLATNKIIFLNSFKMKLSIIFGVVHMIFGVCMSLVNHNHFNRRVNILLEFIPQMMFLVLLFAYM 572

  Fly   648 VFLIFYKWMSYGG-----H-KPAPYNAACAPSVLITFINMMLMKKEDPVENCLDYMYPNERMIEF 706
            .|::|:||:.|..     | ||     .|||||||.||||||.|.::|::.|.::|:..:..::.
Mosquito   573 CFMMFFKWIMYSAVTDEDHLKP-----GCAPSVLIMFINMMLFKNQEPLDTCKEFMFEGQDTLQV 632

  Fly   707 ALVGIAFCTIPILLAGKPIYLMRRRRKMQQERERDFKRMRRQTIAEMRSTMRYTDDDNSETSRQ- 770
            ..:.:....||.||..||.|:|             |||..:.|            :..||.:.|
Mosquito   633 IFIVLGLICIPWLLLAKPFYIM-------------FKRKGKST------------EHGSEVAHQS 672

  Fly   771 -KSVDNEEEHEMSEIWIHSGIHTIETVLGSVSHTASYLRLWALSLAHDQLSDVLWHMVLTKGFAN 834
             .|.::.::..||||:||..|||||.:|.::||||||||||||||||.|||:||::||.|.|..|
Mosquito   673 SSSSNHHDDEPMSEIFIHQAIHTIEYILSTISHTASYLRLWALSLAHAQLSEVLYNMVFTIGLRN 737

  Fly   835 TLPLYYGVPVLMATFFAWAILTVAILVMMEGLSAFLHTLRLHWVEFQSKFFGGAGESFKAFNF 897
              ..|.|..::...|:.|::||:.|||.||||||||||||||||||.|||:.|.|.:||.|:|
Mosquito   738 --DSYVGAIMIWLVFWPWSVLTIGILVGMEGLSAFLHTLRLHWVEFMSKFYEGLGYAFKPFSF 798

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vha100-3	NP_725837.1	V_ATPase_I	38..897	CDD:460232	299/881 (34%)
LOC1281585	XP_321519.1	V_ATPase_I	27..798	CDD:460232	299/882 (34%)