Protein Alignment Vha100-3 and atp6v0a1

DIOPT Version :9

• Sequence 1: NP_725837.1
• Gene: Vha100-3 / 246543
• FlyBaseID: FBgn0028669
• Length: 904
• Species: Drosophila melanogaster
• Sequence 2: XP_031749790.1
• Gene: atp6v0a1 / 100036694
• XenbaseID: XB-GENE-959346
• Length: 871
• Species: Xenopus tropicalis
• Alignment Length: 914
• Identity: 322/914 - (35%)
• Similarity: 493/914 - (53%)
• Gaps: 114/914 - (12%)

  Fly    15 FRSEDMDLCQLLLHTENAFDCLIEVGHHGAVQFNNVYDEDRLLNNLYSKKVTQCYEL---LRIVD 76
            ||||:|.|.||.|.:|.|:.|:.|:|..|.|||.::..:..:....:..:|.:|.|:   ||.|:
 Frog    31 FRSEEMTLAQLFLQSEAAYCCVSELGELGKVQFRDLNPDVNVFQRKFVNEVRRCEEMDRKLRFVE 95

  Fly    77 ----SLHTYIVQLHVN-EIFYPDVDRENRLKEKDLAKYSDSLKRIHVEASAVTEHYYRLDSRRNR 136
                ..:..|:....| |:.:|          :|:.....:.::|.:|...:..:...|......
 Frog    96 KEVKKANISILDTGENPEVPFP----------RDMIDLEANFEKIEIELKEINTNQEALKRNFLE 150

  Fly   137 MMEHSFALNKANKYM-------VSDMGSELLYSESTVIGLVQDATTTSGAYPAHLNYMIGCIRAD 194
            :.|..|.|.|..::.       ...|....|..||:  .|::.:....|| |..|.::.|.|..:
 Frog   151 LTELKFILRKTQQFFDEAQLHHHQQMADPDLLEESS--SLLEPSEMGRGA-PLRLGFVAGVINRE 212

  Fly   195 KFYSFELLLYRLCSFNLIIRFSEMPSPVYEYHYGYKPERVRKFAILMMASSTMIWPKVLKICAHY 259
            :..:||.:|:|:|..|:.:|.:|:.:|:.:...|   :.|.|...::......:..:|.|||..:
 Frog   213 RIPTFERMLWRVCRGNVFLRQAEIENPLEDPVTG---DSVHKSVFIIFFQGDQLKNRVKKICEGF 274

  Fly   260 HVNIYDCPSSASQREDKVKELSQEIVNVEKVLKEAELMRRQILEVAGRDLFIIRVNLRKALKVYD 324
            ..::|.||.:..:|::....::..|.:::.||.:.|..|:::|:.|.:.|.:..:.:||...:|.
 Frog   275 RASLYPCPETPQERKEMATGVNTRIEDLQMVLNQTEDHRQRVLQAAAKSLRVWFIKVRKMKAIYH 339

  Fly   325 LMNRLRLVGGVEV-PRYLLAEVYIPSSDVPEVEVILRNASRISGGADNIDSSDEDEMNDMKTMPN 388
            .:|    :..::| .:.|:|||:.|.:|:..::..||..:..||                    :
 Frog   340 TLN----LCNIDVTQKCLIAEVWCPVADLDSIQFALRRGTEHSG--------------------S 380

  Fly   389 TTPYPIEADFQPLEDMSAGAILLKKNRL-VNHMPPTYFRLNKFTRGFQNLIDAYGMADYKELNPA 452
            |.|                :||   ||: .|..||||.:.||||.|||||:||||:..|:|:|||
 Frog   381 TVP----------------SIL---NRMQTNQTPPTYNKTNKFTYGFQNLVDAYGIGSYREINPA 426

  Fly   453 PYTIITFPFLFAVMFGDLGHGILLILFSSLMIWKHREIEKYQINATSENEILNILYAGRYIILLM 517
            |||||||||||||||||.|||||:.||:..|:.:...|...:|    :||:..::::||||||||
 Frog   427 PYTIITFPFLFAVMFGDFGHGILMTLFAVWMVVRESRILSQKI----DNELFTMMFSGRYIILLM 487

  Fly   518 GVFSVYMGLVYNIVMAKGFNLFGSSWSCR--YNETTVYDPAFHVTLDSSHPH---FYSGHPYPLG 577
            |:||:|.||:||...:|..||||||||.|  :.:|...|...|.::...:|:   .::| |||.|
 Frog   488 GLFSIYTGLIYNDCFSKALNLFGSSWSVRPMFTDTWSEDLLKHTSVLQLNPNVTGVFNG-PYPFG 551

  Fly   578 MDPVWAVCGQDSITTTNSLKMKMAIVLGISQMMFGLGLAAANCVLMNRKADLILVVIPQMIFMLC 642
            :||:|:: ..:.:|..||.||||::||||..|.||:.|:..|.:...:..::.|..||:||||..
 Frog   552 IDPIWSL-ATNKLTFLNSFKMKMSVVLGIIHMTFGVALSLLNHIYFKKPLNIYLGFIPEMIFMTT 615

  Fly   643 LFGYLVFLIFYKWMSYGGHKPAPYNAACAPSVLITFINMMLMKKEDPVENCLDYMYPNERMIEFA 707
            ||||||.||.|||.:|...     .:..|||:||.||||.|...:|   ..|..:|..:..::..
 Frog   616 LFGYLVILIIYKWCAYDAS-----TSMVAPSLLIHFINMFLFSYQD---TSLPMLYKGQMGLQCF 672

  Fly   708 LVGIAFCTIPILLAGKPIYLMRRRRKMQQERERDFKRMRRQTIAEMRSTMRYTDDDNSETSR-QK 771
            ||..|...:|.:|..||:.|  ||:.:::      |.:.......:|.....|::|...... |.
 Frog   673 LVVCAIICVPWMLVVKPLIL--RRQYLRR------KHLGTHNFGGIRVGNGPTEEDAEIIQHDQL 729

  Fly   772 SVDNEEEHE--MSEIW------IHSGIHTIETVLGSVSHTASYLRLWALSLAHDQLSDVLWHMVL 828
            |:.:||..|  |.|::      :|..|||||..||.:|:||||||||||||||.|||:|||.||:
 Frog   730 SMHSEEGEEPAMEEVFDFGDTVVHQAIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWTMVM 794

  Fly   829 TKGFANTLPLYYGVPVLMATFFAWAILTVAILVMMEGLSAFLHTLRLHWVEFQSKFFGGAGESFK 893
            ..|.  ::....|...|:..|.|:|.||:|||::|||||||||.|||||||||:||:.|.|..|.
 Frog   795 HVGL--SIRSLGGGIALVFVFSAFATLTIAILLIMEGLSAFLHALRLHWVEFQNKFYMGTGFKFL 857

  Fly   894 AFNF 897
            .|:|
 Frog   858 PFSF 861

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vha100-3	NP_725837.1	V_ATPase_I	38..897	CDD:279793	309/889 (35%)
atp6v0a1	XP_031749790.1	V_ATPase_I	53..861	CDD:396194	309/890 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D164762at33208
OrthoFinder	1	1.000	-	-		FOG0000328
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11629
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.020