Protein Alignment Sema2b and Sema6b

DIOPT Version :9

• Sequence 1: NP_001261024.1
• Gene: Sema2b / 246538
• FlyBaseID: FBgn0264273
• Length: 824
• Species: Drosophila melanogaster
• Sequence 2: XP_006244410.1
• Gene: Sema6b / 84609
• RGDID: 69278
• Length: 957
• Species: Rattus norvegicus
• Alignment Length: 637
• Identity: 204/637 - (32%)
• Similarity: 309/637 - (48%)
• Gaps: 111/637 - (17%)

  Fly   131 NNALYVGAMDRIFRLNLR-NISQSICERDVLILEPTGSDILNCVSKGKREKVECRNHIRVIQPMN 194
            |..|::|..|.::::.|. :.|..:..:..|......|||..|..|||:|. ||||.::|:  :.
  Rat   145 NRTLFIGDRDNLYQVELEPSTSTELRYQRKLTWRSNPSDIDVCRMKGKQEG-ECRNFVKVL--LL 206

  Fly   195 FNGQKLYVCGTNAHNPKDYVINANLTHLPRSQYVPGIGLGIGKCPYDPADNSTAVYVENGNPFGL 259
            .:...|:|||:||.||    |.||.: :...|.:.....|:.:|||||...:.|::.:.
  Rat   207 RDESTLFVCGSNAFNP----ICANYS-MDTLQLLGDNISGMARCPYDPKHANVALFSDG------ 260

  Fly   260 PALYAGTNAEFTKADSVIFRS--DLYNLTNGRKEANFKRTVKYDSKLLDKPNFVGSFEIGEFVYF 322
             .|:..|..:|...|:||:||  |...|          ||||:|||...:|.||.:.|.|..|||
  Rat   261 -MLFTATVTDFLAIDAVIYRSLGDRPTL----------RTVKHDSKWFKEPYFVHAVEWGSHVYF 314

  Fly   323 FFREHAVEYINCGKAVYSRVARVCKNDRGGK-YMISQNWATYLKARMNCSISSEFPFYFNEIQSV 386
            ||||.|:|:....|.|.||||||||||.||. .::.:.|.::||||:|||:..:..||||.:|:|
  Rat   315 FFREIAMEFNYLEKVVVSRVARVCKNDVGGSPRVLEKQWTSFLKARLNCSVPGDSHFYFNVLQAV 379

  Fly   387 YKMPTDDTK--FYATFTTNTNGLIGSAVCSYDIRDINAAFDGKFKEQATSNSAWLPVLNSKVPEP 449
            ..:.:...:  ..|.|:|.:|.:.|||||::|:..:.|.|:|:|:||.:..|.|.||...:||.|
  Rat   380 TGVVSLGGRPVILAVFSTPSNSIPGSAVCAFDMNQVAAVFEGRFREQKSPESIWTPVPEDQVPRP 444

  Fly   450 RPGTC------HNDTATLPDSVLNFIRKHPLMDKAVDHEFGNPVFFKRDVI---LTKLVVDKIRI 505
            |||.|      :|.:..|||.:|||::.|||||:||. ..|:..:..|.:|   ||::.|| :..
  Rat   445 RPGCCAAPGMQYNASNALPDEILNFVKTHPLMDEAVP-SLGHSPWIVRTLIRHQLTRVAVD-VGA 507

  Fly   506 DKLNQEFLVYF-----------------VATTSGHIYKIVQFMHY-----GQRHSNLVDIFEASP 548
            .....:.:|:.                 |:.|:|....:.:|..|     |:..|       |..
  Rat   508 GPWGNQTIVFLGSEVGTVLKFLVKPNASVSGTTGPSIFLEEFETYRPDRCGRSSS-------AGE 565

  Fly   549 HSEPIREMTLSHKTGSLYVATDHQVKQIDIAMCARRYDSCFR-CV--SDPYCGWDKDVNAC---R 607
            ..:.:..:.|...:|.|..|....|.::.:|.| :.|..|.: |:  .||||||..| .:|   |
  Rat   566 WGQRLLSLELDAASGGLLAAFPRCVVRVPVARC-QLYSGCMKNCIGSQDPYCGWAPD-GSCIFLR 628

  Fly   608 PYQLGLL-QDVAN-ETSGICD-TSVLRKK--------------VTSSYGQTLHLSCFVKMPEVLR 655
            |...... |||:. .|||:.| |.:||..              ||||      ::.|| :..|:.
  Rat   629 PGTSATFEQDVSGASTSGLGDCTGLLRASLSDDRAGLVSVNLLVTSS------VAAFV-VGAVVS 686

  Fly   656 KKQTRWYHHSTEKGRYEVRYTPTKYIDTNEGGLVLLAVNE-------GDGGR 700
            .....|:....|: |...|....:.|..:.|...:|:|:.       |.|||
  Rat   687 GFSVGWFVGLRER-RELARRKDKEAILAHGGSEAVLSVSRLGERRGTGTGGR 737

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema2b	NP_001261024.1	Sema_2A	120..579	CDD:200499	160/484 (33%)
		Ig	632..720	CDD:299845	19/90 (21%)
Sema6b	XP_006244410.1	Sema_6B	128..596	CDD:200528	160/484 (33%)
		PSI	597..>626	CDD:279745	12/30 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3611
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11036
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910