Protein Alignment Sema2b and sema4ab

DIOPT Version :9

• Sequence 1: NP_001261024.1
• Gene: Sema2b / 246538
• FlyBaseID: FBgn0264273
• Length: 824
• Species: Drosophila melanogaster
• Sequence 2: XP_005170153.1
• Gene: sema4ab / 571290
• ZFINID: ZDB-GENE-060503-363
• Length: 836
• Species: Danio rerio
• Alignment Length: 625
• Identity: 164/625 - (26%)
• Similarity: 272/625 - (43%)
• Gaps: 124/625 - (19%)

  Fly   124 TFYMDERNNALYVGAMDRIFRLNLRNISQSICERDVLILEPTGSDILNCVSKGKREKVECRNHIR 188
            |..:......|:|||.|.|..:|:.....::.|:  |...|:..|..:|..|||. |::|.|.:|
Zfish    51 TLLLSNDEGTLFVGARDTILSINISQTDMTLKEK--LDWSPSEKDFNDCSMKGKL-KMDCHNFVR 112

  Fly   189 VIQPMNFNGQKLYVCGTNAHNPKDYVINANLTHL-------PRSQYVPGIGLGIGKCPYDPADNS 246
            |:|.:  |...:|.|||.|.:|:...||:....:       |..        |.|:|||||...:
Zfish   113 VLQVL--NSTHMYACGTFAFSPRCIYINSQTFTMVTGPSGKPEE--------GRGRCPYDPYQKN 167

  Fly   247 TAVYVENGNPFGLPALYAGTNAEFTKADSVIFRSDLYNLTNGRKEANFKRTVKYDSKL--LDKPN 309
            :|:.|:.       .||.||.::|.....||.|    :|:.|...     .:|.|..|  |:.|.
Zfish   168 SAITVDG-------ELYTGTVSDFRGTRPVISR----HLSEGSHV-----DLKLDDTLGWLEDPT 216

  Fly   310 FVGSFEI--GEFVYFFFREHAVEYINCGKAVYSRVARVCKNDRGGKYMISQNWATYLKARMNCSI 372
            |:.|..|  .|.|||||.|...||....|...||||:||.:|.||:..:.:.|.|:.||::.|..
Zfish   217 FISSTYIHSEEKVYFFFSEIGKEYDFIDKFTVSRVAQVCTSDVGGQRTLQKRWTTFAKAQLLCQA 281

  Fly   373 SSEFPFYFNEIQSVYKM------PTDDTKFYATFTTNTNGLIG-SAVCSYDIRDINAAFDGKFKE 430
            ..|.|  :|.:|.|..:      ..|:|.||..||:.....:| ||||::.::||...|.|::|.
Zfish   282 DQELP--YNVLQDVISLSPPEGASEDETLFYGIFTSQWRVNLGRSAVCAFSLKDIKKVFTGRYKV 344

  Fly   431 QATSNSAWLPVLNSKVPE--PRPGTC--HNDTATLPDSVLNFIRKHPLMDKAV------------ 479
            .......|    :::|.|  ..||.|  ||.:    |:.|.|::.:.|.||:|
Zfish   345 LNRDTLKW----STRVQEQMANPGECGLHNAS----DNTLRFVKDNFLADKSVLPVNQGLTVVSP 401

  Fly   480 DHEFGNPVFFKRDVILTKLVVDKIRIDKLNQEFLVYFVATTSGHIYKIVQFMHYGQRHSNLVDIF 544
            |..:.|            :...::: ....:.:.|.::.|.||.::|.|..    ::.:::::..
Zfish   402 DKSYSN------------IAAQRVQ-GARGKYYTVLYLLTESGFLHKTVLL----KKGAHIIEEI 449

  Fly   545 EASPHSEPIREMTLSHKTGSLYVATDHQVKQIDIAMCARRYDSCFRCV--SDPYCGWDKDVNACR 607
            :.....:.::.:.||...|::.:.:...:..:.::.|: .|.||..||  .||:||||.....|:
Zfish   450 QVFHQPQMVKSLLLSVSKGAVLIGSSEGLLSVPVSNCS-HYRSCAECVLARDPFCGWDLSQRVCK 513

  Fly   608 ---PYQLGLLQDV-ANETSGICDTSVLRKK----------------VTSSYGQTLHLSCFVKMPE 652
               ..|..|.||| ..:.|..|.:..||.:                ::.|..:.::|.|    ||
Zfish   514 LITTSQNQLAQDVDEGKVSEQCSSVNLRSRSGQPQNTQTLCPPGEVLSVSLNEVINLQC----PE 574

  Fly   653 VLRKKQTRWYHHSTEKGRYEVRYTPTKYIDTNEGGLVLLA 692
            .....:..|       .|...:.:|..:|.:..|.|..:|
Zfish   575 ASNLAKCHW-------ERLNSQLSPKIFIQSVNGSLSFVA 607

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema2b	NP_001261024.1	Sema_2A	120..579	CDD:200499	130/488 (27%)
		Ig	632..720	CDD:299845	12/77 (16%)
sema4ab	XP_005170153.1	Sema_4	41..484	CDD:200501	130/488 (27%)
		PSI	485..>512	CDD:214655	12/27 (44%)
		Ig	555..631	CDD:299845	12/64 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3611
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11036
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910