Protein Alignment Sema2b and sema6ba

DIOPT Version :9

• Sequence 1: NP_001261024.1
• Gene: Sema2b / 246538
• FlyBaseID: FBgn0264273
• Length: 824
• Species: Drosophila melanogaster
• Sequence 2: NP_001353244.1
• Gene: sema6ba / 562398
• ZFINID: ZDB-GENE-131024-1
• Length: 872
• Species: Danio rerio
• Alignment Length: 724
• Identity: 221/724 - (30%)
• Similarity: 333/724 - (45%)
• Gaps: 172/724 - (23%)

  Fly   106 RHHKEHVQDFSCGPLHYKTFYMDERNNALYVGAMDRIFRLNLRNISQSICERDVLIL------EP 164
            |.|:.:.:.   .||:.:|..  ..|..||:||.|.::|:.|.::|     .|.:..      |.
Zfish    46 RAHRSYTRQ---EPLYIQTVL--RVNRTLYIGARDDLYRVELDHVS-----GDEMFYSKKRTWES 100

  Fly   165 TGSDILNCVSKGKREKVECRNHIRVIQPMNFNGQKLYVCGTNAHNPKDYVINANLTHLPRSQYVP 229
            ..:||..|..|||.|: ||||:|:|:  ::.:| .|:||||||.||    :.||.|.    ..:.
Zfish   101 NKNDIRICRMKGKHEE-ECRNYIKVL--LSHDG-GLFVCGTNAFNP----LCANYTR----DTLE 153

  Fly   230 GIG---LGIGKCPYDPADNSTAVYVENGNPFGLPALYAGTNAEFTKADSVIFRSDLYNLTNGRKE 291
            .:|   .|:.:|||||...:.|::.|.       :|:.||..:|...|:||:||        ..|
Zfish   154 LVGEPISGMARCPYDPKHANVALFAEG-------SLFTGTVTDFLAIDAVIYRS--------LGE 203

  Fly   292 ANFKRTVKYDSKLLDKPNFVGSFEIGEFVYFFFREHAVEYINCGKAVYSRVARVCKNDRGG-KYM 355
            :...||:|:|||...:|.||.:.|.|..:||||||.|:|:....|.:.||||||||.|.|| :.:
Zfish   204 SPALRTIKHDSKWFREPYFVSAVEWGPHIYFFFREMAMEFNYLEKVMVSRVARVCKGDLGGSQRV 268

  Fly   356 ISQNWATYLKARMNCSISSEFPFYFNEIQS---VYKMPTDDTKFYATFTTNTNGLIGSAVCSYDI 417
            :.:.|.::||||:||||..:..||||.:||   :.:|...|. ....|:|.:|.:.|||||::|:
Zfish   269 LERQWTSFLKARLNCSIPGDSHFYFNLLQSTSPIIRMQGRDV-ILGVFSTPSNSIPGSAVCAFDM 332

  Fly   418 RDINAAFDGKFKEQATSNSAWLPVLNSKVPEPRPGTC------HNDTATLPDSVLNFIRKHPLMD 476
            :.:...|:|:||||.:..|.|.||.:..||.||||.|      .:.:.||||.|||||:.|||||
Zfish   333 QQLARVFEGRFKEQKSPESIWTPVPDELVPRPRPGGCAVQGSRFSTSNTLPDEVLNFIKIHPLMD 397

  Fly   477 KAVDHEFGNPVFFKRDVI--------LTKLVVDKIRIDKLNQEFLVYFVATTSGHIYKIVQFMHY 533
            :||      |:...|..|        |..:|||.......|:  .|.|:.:|.|.:.|.:.....
Zfish   398 EAV------PLLGHRPWIVKTMVRYQLNTMVVDTEAGPHRNR--TVVFLGSTRGTVLKFLITPSP 454

  Fly   534 GQRHSNLVDIFEASPHSEPIR------------EMTLSHKTGSLYVATDHQVKQIDIAMCARRYD 586
            ..::||.....|......|.|            .:||...:.:|.:|....|.::.:|.| ..:.
Zfish   455 ENQYSNTNTFLEELEGYNPERCGDDSAQAMQPLSLTLDKPSHTLLLAFHSCVVRVPVARC-HLHS 518

  Fly   587 SCFR-CVS--DPYCGWDKDVNAC---RP-YQLGLLQDVANETSGICDTSVLRKKVTSSYGQTLHL 644
            .|.: |::  ||||||.:. :.|   || .:|..:|||                   .||.|.||
Zfish   519 RCMKNCIASRDPYCGWTRG-STCTLLRPGTRLPFVQDV-------------------EYGNTSHL 563

  Fly   645 -SC-------FVKMPEVLRKKQTRWYHHSTEKGRYEVRYTPTKYIDTNEGGLVLLAVNEGDGGRY 701
             .|       |:..||.|                          :..|.  ||:.||:....|
Zfish   564 GDCDGLLRESFMDEPESL--------------------------VTLNL--LVVAAVSAFSTG-- 598

  Fly   702 DSYLDGTLLCSYGVTVDAHRCSPPSQKQDYQKIYSHWCNEFEKYKSAMKQWQAKQEQCGL-KDKT 765
             :.|.|..:|........||              ||     ....|:..|.::::|:|.: :.::
Zfish   599 -AALSGLAVCWIMGQKHRHR--------------SH-----SNTPSSSIQRKSEKERCMMGQSRS 643

  Fly   766 GPISSNGKH 774
            |.:.|..:|
Zfish   644 GSVMSVSRH 652

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema2b	NP_001261024.1	Sema_2A	120..579	CDD:200499	171/497 (34%)
		Ig	632..720	CDD:299845	19/95 (20%)
sema6ba	NP_001353244.1	Sema_6B	49..512	CDD:200528	172/508 (34%)
		PSI	513..>542	CDD:307546	10/30 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11036
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.010