Protein Alignment Sema2b and si:dkey-49n23.1

DIOPT Version :9

• Sequence 1: NP_001261024.1
• Gene: Sema2b / 246538
• FlyBaseID: FBgn0264273
• Length: 824
• Species: Drosophila melanogaster
• Sequence 2: XP_021329223.1
• Gene: si:dkey-49n23.1 / 558742
• ZFINID: ZDB-GENE-050208-762
• Length: 758
• Species: Danio rerio
• Alignment Length: 628
• Identity: 191/628 - (30%)
• Similarity: 299/628 - (47%)
• Gaps: 83/628 - (13%)

  Fly   122 YKTFYMDERNNALYVGAMDRIFRLNLRNISQSICERDVLILEPTGSD-ILNCVSKGKREKVECRN 185
            |:...:||....|.||..|.|:.||    |.|:.:....|..|.|.: |..|...||...::|.|
Zfish    57 YQALLLDEDRGWLLVGGRDHIYMLN----SDSLTQPSRKIHWPAGQEHIERCKYAGKNLSMDCAN 117

  Fly   186 HIRVIQPMNFNGQKLYVCGTNAHNPK-DYVINANLTHLPRSQYVPGIG-LGIGKCPYDPADNSTA 248
            ::|::||  ||...:|||||.|.:|: .|:...:....|..|.:..:| .|.||||:.|.:..||
Zfish   118 YVRLLQP--FNKTHVYVCGTGAFHPQCTYIDLGHNLEKPTFQLLSHVGESGRGKCPFSPQEPFTA 180

  Fly   249 VYVENGNPFGLPALYAGTNAEFTKADSVIFRSDLYNLTNGRKEANFKRTVKYDSKLLDKPNFVGS 313
             ::.:|.      |||||..:|...::.|||:.:::     ...::.||..|....|::|.||||
Zfish   181 -HLTDGE------LYAGTAVDFMGTNAAIFRTSVHS-----NNQHYIRTEAYQDHWLNEPEFVGS 233

  Fly   314 FEI-------GEFVYFFFREHAVEYINCGKAVYSRVARVCKNDRGGKYMISQNWATYLKARMNCS 371
            :.|       .:.|||||:|.|||.....|.:|||||||||||.|||..:...|:|:||||:.|:
Zfish   234 YSIPDTHSLDDDKVYFFFKETAVESNQLDKRIYSRVARVCKNDIGGKRSLINRWSTFLKARLVCT 298

  Fly   372 ISSE--FPFYFNEIQSVYKMPTDDTK---FYATFTTNTNGLIGSAVCSYDIRDINAAFDGKFKEQ 431
            :...  ...:|:|::.::.:.|.|.:   .|..|:|:::...|||||.|.:..|.|||:|.|..:
Zfish   299 VPGPGGMDTHFDELEDIFLLETKDPQNPVIYGVFSTSSSVFRGSAVCVYSMASIRAAFNGPFAHK 363

  Fly   432 ATSNSAWLPVLNSKVPEPRPGTC--------HNDTATLPDSVLNFIRKHPLMDKAVDHEFGNPVF 488
            .:.:..|:. ...|:|.||||||        :..|...||.|::|:|.|.||.:.|......|||
Zfish   364 ESPDYRWME-YKGKIPYPRPGTCPSETYDALYKSTRDFPDDVVSFMRAHQLMWEPVVPIHRRPVF 427

  Fly   489 FKRDV--ILTKLVVDKIRIDKLNQEFLVYFVATTSGHIYKIVQFMHYGQRHSNLV----DIFEAS 547
            .:.:.  .|.|||||  |:|..:.::.|..:.|..|.:.|:|...........::    ::|:.
Zfish   428 TRINTPYRLKKLVVD--RVDAEDGQYDVLHLGTDDGRVLKVVSVPKENWEIEEIILEELNVFKT- 489

  Fly   548 PHSEPIREMTLSHKTGSLYVATDHQVKQIDIAMCARRYDSCFRC--VSDPYCGWDKDVNACRPY- 609
              ..||..|.||.|...|::::|..|.|:.:..|.....:|..|  ..||||.||.  ::|..|
Zfish   490 --QTPILSMELSTKRQVLFISSDENVVQLPVQRCELYGKACVDCCLARDPYCAWDG--SSCTNYF 550

  Fly   610 ----QLGLLQDVA-----NETSGICDTSVLRKKVTSSYG---QTLHLSCFVKMPEVLRKKQTRWY 662
                :....|||.     ::...:.|.|. ..::.:.||   .:..|.|....|:...|...:..
Zfish   551 PSNKRRARRQDVRYGDPWSQCQDMRDGSE-NAELKTVYGVETNSTFLECVSNSPQATIKWIFQPN 614

  Fly   663 HHSTEK----GRYEVRYTPTKYIDTNEGGLVLLAVNEGDGGRY 701
            |....|    |...:.:.        :.||:|..:...:.|.|
Zfish   615 HSQNSKELVPGEENLLHM--------QRGLLLQQITSTNAGLY 649

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema2b	NP_001261024.1	Sema_2A	120..579	CDD:200499	161/485 (33%)
		Ig	632..720	CDD:299845	14/77 (18%)
si:dkey-49n23.1	XP_021329223.1	Sema_3	48..521	CDD:200500	161/487 (33%)
		PSI	520..557	CDD:214655	11/38 (29%)
		Ig_Semaphorin_classIII	581..672	CDD:143279	14/77 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	68	1.000	Domainoid score	I9670
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D153798at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11036
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X596
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	6.020