Protein Alignment Sema2b and sema4f

DIOPT Version :9

• Sequence 1: NP_001261024.1
• Gene: Sema2b / 246538
• FlyBaseID: FBgn0264273
• Length: 824
• Species: Drosophila melanogaster
• Sequence 2: XP_005166611.1
• Gene: sema4f / 556003
• ZFINID: ZDB-GENE-130530-860
• Length: 797
• Species: Danio rerio
• Alignment Length: 654
• Identity: 175/654 - (26%)
• Similarity: 266/654 - (40%)
• Gaps: 121/654 - (18%)

  Fly   124 TFYMDERNNALYVGAMDRIFRLNLRNISQSICERDVLILEPTGSDILNCVSKGKREKVECRNHIR 188
            ||.:...:..||:||.|.:..::...:|:.:.|..|    |.... .:||:|||.|. :|||::|
Zfish    43 TFLLHSESGMLYLGARDAVIVVDTAKLSKKMIEWSV----PEDRR-KSCVAKGKTED-DCRNYVR 101

  Fly   189 VIQPMNFNGQKLYVCGTNAHNPKDYVINANLTHLPRSQ--YVPGIGLGIGKCPYDPADNSTAVYV 251
            :::.:: :| ::|.|||.|.:|:...||.:...|.:..  ::. :..|.||||::|:...|||..
Zfish   102 LLEFLD-DG-RIYACGTFAFDPQCAFINISTFSLEKQDDGFIK-METGKGKCPFEPSQPYTAVMA 163

  Fly   252 ENGNPFGLPALYAGTNAEFTKADSVIFRSDLYNLTNGRKEANFKRTVKYDSKLLDKPNFVGSFEI 316
            ..       .||....:.|.        ..:|:::........:...:.....|..|.|:.|..|
Zfish   164 GG-------ILYTAVTSNFL--------GTMYDISRATGIEQERIRTEQSINWLSDPEFISSAFI 213

  Fly   317 GE-----------FVYFFFREHAVEYINCGKAVYSRVARVCKNDRGGKYMISQNWATYLKARMNC 370
            .|           .:||||.|.|.||....|....|||||||:|.||...:.:.|.|:|||::.|
Zfish   214 QEDAKNNPTGEDDKIYFFFTEVAKEYDLYTKVKVPRVARVCKSDVGGMKTLQRRWTTFLKAQLVC 278

  Fly   371 S--ISSEFPFYFNEIQSVYKMPTD--DTKFYATFTTNTNGLIGSAVCSYDIRDINAAFDGKFKEQ 431
            .  .|.:......::.:|...|.|  .|.||..||:.......||||.|.:.:|....:|.|||.
Zfish   279 EDRASGQRFNILTDVFTVQHQPGDPSSTHFYGIFTSQWEREELSAVCVYSLEEITKVMNGPFKEL 343

  Fly   432 ATSNSAWL-PVLNSKVPEPRPGTCHN---------DTATLPDSVLNFIRKHPLMDKAVDHEFGNP 486
            ..|...|: |   ..:|.||||.|.|         .:..|||.||.|:|.||||:.:|   ...|
Zfish   344 KKSCENWINP---EPIPTPRPGQCLNSDQRELGFESSLKLPDKVLTFMRDHPLMENSV---VAVP 402

  Fly   487 VFFKRDVILTKLVVDKIRIDKLNQEFLVYFVATTSGHIYKIVQFMHYGQRHSNLVDIFEASPHSE 551
            :..:..:..|||.|      .|...|        ||....|...:|.|..|..|..:....|::.
Zfish   403 LMIRYGITYTKLAV------TLTPAF--------SGQKQHITTVLHLGTDHGELHKVAVVGPNAT 453

  Fly   552 PIREMTLSHK----------TGSLYVATDHQVKQIDIAMCARRYDSCFRC--VSDPYCGWDKDVN 604
            .|.|:||...          .|...|.:.|.:.::.|..|: .|.||..|  .....|.|..:..
Zfish   454 LIEEITLFSAQEPVNNILLYKGEAVVGSPHSLVKLPILGCS-LYSSCEVCARAGGLGCIWRHNRP 517

  Fly   605 AC---RPYQLGLLQDV---ANETSGICDTSVLRKKVTSSYGQTLHLSCFVKMPEVLRKKQTRWYH 663
            ||   :|.::...:|:   .|:..|:|...|:..:|..  |..:.|||....|     :...|.|
Zfish   518 ACAMAKPGEVVEAEDLVRQCNKREGLCSPPVIEMRVVE--GLRVLLSCVQLSP-----RPCHWDH 575

  Fly   664 HSTEKGRYEVRYTPTKYIDTNEGGLVLLAVNEGDGGRYDSYLDGTLLCSYGVTVDAHRCSPPSQK 728
            ......|:. .|.....|.....|:.:                  .||.     :|.|..||.:|
Zfish   576 PPGSHTRHH-NYDLEVQITNKSLGIYV------------------CLCD-----EAGRDQPPCRK 616

  Fly   729 QDYQ 732
            ..||
Zfish   617 AVYQ 620

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema2b	NP_001261024.1	Sema_2A	120..579	CDD:200499	138/491 (28%)
		Ig	632..720	CDD:299845	14/87 (16%)
sema4f	XP_005166611.1	Sema	36..490	CDD:301699	138/490 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11036
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100