Protein Alignment Sema2b and sema6ca

DIOPT Version :10

• Sequence 1: NP_001261024.1
• Gene: Sema2b / 246538
• FlyBaseID: FBgn0264273
• Length: 824
• Species: Drosophila melanogaster
• Sequence 2: XP_068071205.1
• Gene: sema6ca / 406272
• ZFINID: ZDB-GENE-040426-1933
• Length: 934
• Species: Danio rerio
• Alignment Length: 642
• Identity: 199/642 - (30%)
• Similarity: 309/642 - (48%)
• Gaps: 106/642 - (16%)

  Fly   134 LYVGAMDRIFRLNLRNISQSICERDVLILEPTGSDILNCVSKGKREKVECRNHIRVIQPMNFNGQ 198
            ||:.|.|.:|.:||......|..:.:|....|  |:..|..:| |...||.|:|:|:.|.  |.:
Zfish   120 LYIAARDHVFVVNLTTAVDEIIPQQILTWRST--DVSKCTVRG-RNSDECYNYIKVLVPR--NDE 179

  Fly   199 KLYVCGTNAHNP--KDYVINANLTHLPRSQYVPGIG---LGIGKCPYDPADNSTAVYVENGNPFG 258
            .|:.|||||.||  ::|          |...:..:|   ||..:||::...::..|:.  |..|
Zfish   180 TLFACGTNALNPACRNY----------RLSSLEQVGQELLGQARCPFESRQSNVGVFA--GGHF- 231

  Fly   259 LPALYAGTNAEFTKADSVIFRSDLYNLTNGRKEANFKRTVKYDSKLLDKPNFVGSFEIGEFVYFF 323
                |:.|..:|..:|:||:||      .|.:.....||||||||.|.:|:|:.:.|.|.:||||
Zfish   232 ----YSATVTDFQASDAVIYRS------LGGEGRPVLRTVKYDSKWLREPHFLHAVEYGNYVYFF 286

  Fly   324 FREHAVEYINCGKAVYSRVARVCKNDRGGK-YMISQNWATYLKARMNCSISSEFPFYFNEIQSVY 387
            |.|.|||:...||.||||||||||||.||. .::.::|.::||||:|||:..:..|||:.:||:.
Zfish   287 FSEIAVEHTAAGKVVYSRVARVCKNDNGGSTRVLDRHWTSFLKARLNCSVPGDTFFYFDVLQSLT 351

  Fly   388 KMPTDDTK--FYATFTTNTNGLIGSAVCSYDIRDINAAFDGKFKEQATSNSAWLPVLNSKVPEPR 450
            .:...:.:  ....|||.||.:.|||||.:.:.||...|:|:||||..|:|.|..|...:||:||
Zfish   352 NVLQINQRPAVVGVFTTQTNSIPGSAVCGFYLDDIERVFNGRFKEQKNSDSMWTAVPEEQVPKPR 416

  Fly   451 PGTC--------HNDTATLPDSVLNFIRKHPLMDKAVDHEFGNPVF------FKRDVILTKLVVD 501
            ||:|        ::.:...|||||:||:.||||:::|......|:.      :|    ||::|||
Zfish   417 PGSCAGEGSASSYSSSVQFPDSVLSFIKTHPLMEESVPSVNSQPLITNTASSYK----LTQIVVD 477

  Fly   502 KIRIDKLNQEFLVYFVATTSGHIYKIVQFMHYGQRHSNL----VDIFEAS--PHSEPIREMTLSH 560
            .......|:  .|.|:.:..|.:.||:...|....|::.    :|:|..:  .....:..:.|..
Zfish   478 TAAGPHKNR--TVVFLGSEDGRVLKILTNTHTNSSHTSQLLEDIDVFNPTRCVGERAVLGLELDK 540

  Fly   561 KTGSLYVATDHQVKQIDIAMCARRYDSCFRCV--SDPYCGW---DKDVNACRPYQLGLLQDVANE 620
            :..:|:||....|.::.::.||:......||:  .||||.|   .:..:....::.|..||:..|
Zfish   541 EHHALFVAFSSCVIRVPLSRCAQHATCRRRCLYTHDPYCIWLRTGRCADMAPGFKAGFEQDIDGE 605

  Fly   621 TSGICDTSVLRKKVTSSYGQTL-----HLSCFVKMPEVLRKKQTRWYHHSTEKGRYEVRYTPTKY 680
            .:.:.||..   .|.||.|..:     ..|...::|:.          .|...|          |
Zfish   606 QTHLFDTCT---DVMSSAGSDVKSAVDSASGVKQLPDA----------DSLSDG----------Y 647

  Fly   681 IDTNEGGLVLLAVNEGDGGRYDSYLDGTLLCSYGVTVDAHRCSPPSQKQDYQKIYSH 737
            ..|..|..||||...|      :...|.|:..|     ..:.||.:.:.:....::|
Zfish   648 HFTLLGACVLLAFVLG------AIASGLLVSCY-----CRQSSPSTPEPEATLAHTH 693

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema2b	NP_001261024.1	Sema_2A	120..579	CDD:200499	162/472 (34%)
		PSI	583..>606	CDD:396154	7/27 (26%)
		Ig	632..724	CDD:472250	19/96 (20%)
		Ig strand B	642..646	CDD:409353	0/8 (0%)
		Ig strand C	658..662	CDD:409353	0/3 (0%)
		Ig strand E	686..690	CDD:409353	1/3 (33%)
		Ig strand F	700..705	CDD:409353	0/4 (0%)
		Ig strand G	717..720	CDD:409353	0/2 (0%)
sema6ca	XP_068071205.1	Sema	100..559	CDD:472829	162/472 (34%)