Protein Alignment Sema2b and Sema6c

DIOPT Version :9

• Sequence 1: NP_001261024.1
• Gene: Sema2b / 246538
• FlyBaseID: FBgn0264273
• Length: 824
• Species: Drosophila melanogaster
• Sequence 2: NP_059004.1
• Gene: Sema6c / 29744
• RGDID: 3659
• Length: 960
• Species: Rattus norvegicus
• Alignment Length: 589
• Identity: 185/589 - (31%)
• Similarity: 293/589 - (49%)
• Gaps: 103/589 - (17%)

  Fly    61 SLSALLLVLV----AQTVHVEYARADYENTWNLYYEP-PCCT----GSSAAHHLRHHKEHVQDFS 116
            |:..|||:|:    |||...:              :| |..|    |:|.:...|..::......
  Rat     7 SMPLLLLLLLSLPQAQTAFPQ--------------DPIPLLTSDLQGTSPSSWFRGLEDDAVAAE 57

  Fly   117 CGPLHYKTFYMDERNNALYVGAMDRIFRLNLRNISQSICERDVLI----LEPTGSDILNCVSKGK 177
            .| |.::.|.  ..|..|.|.|.|.:|..:|    |:..|.:.|:    |.....|:.||..:||
  Rat    58 LG-LDFQRFL--TLNRTLLVAARDHVFSFDL----QAQEEGEGLVPNKFLTWRSQDMENCAVRGK 115

  Fly   178 REKVECRNHIRVIQPMNFNGQKLYVCGTNAHNP--KDYVINANLTHLPRSQYVPGIGL-GIGKCP 239
            ... ||.|:|||:.|  ::.|.|..||||:.:|  :.|    .:|.|.:.    |..| |..:||
  Rat   116 LTD-ECYNYIRVLVP--WDSQTLLACGTNSFSPVCRSY----GITSLQQE----GEELSGQARCP 169

  Fly   240 YDPADNSTAVYVENGNPFGLPALYAGTNAEFTKADSVIFRSDLYNLTNGRKEANFKRTVKYDSKL 304
            :|...::.|:..|.       :||:.|.|:|..:|:|::||      .|.:..  .|:.|||||.
  Rat   170 FDATQSTVAISAEG-------SLYSATAADFQASDAVVYRS------LGPQPP--LRSAKYDSKW 219

  Fly   305 LDKPNFVGSFEIGEFVYFFFREHAVEYINCGKAVYSRVARVCKNDRGGK-YMISQNWATYLKARM 368
            |.:|:||.:.|.|:.|||||||.:||....|:..:||||||||.|.||. ..:.::|.::||.|:
  Rat   220 LREPHFVYALEHGDHVYFFFREVSVEDARLGRVQFSRVARVCKRDMGGSPRALDRHWTSFLKLRL 284

  Fly   369 NCSISSEFPFYFNEIQSVYKMPTD---DTKFYATFTTNTNGLIGSAVCSYDIRDINAAFDGKFKE 430
            |||:..:..|||:.:||: ..|.:   .:..:..|||.||.:.|||||::.:.||...|:|||||
  Rat   285 NCSVPGDSTFYFDVLQSL-TGPVNLHGRSALFGVFTTQTNSIPGSAVCAFYLDDIERGFEGKFKE 348

  Fly   431 QATSNSAWLPVLNSKVPEPRPGTC--------HNDTATLPDSVLNFIRKHPLMDKAVDHEFGNPV 487
            |.:.:.||.||...|||.||||:|        .:.:..|||.||.||:.|||:|.||......|:
  Rat   349 QRSLDGAWTPVSEDKVPSPRPGSCAGVGAAALFSSSQDLPDDVLLFIKAHPLLDPAVPPATHQPL 413

  Fly   488 FFKRDVILTKLVVDKIRIDKL---NQEFLVYFVATTSGHIYKIVQFMHYGQR---HSNLVDIFEA 546
            .    .:.::.::.::.:|.:   ::...|.|:.:..|.:.|::.  ..||.   ...:::..:|
  Rat   414 L----TLTSRALLTQVAVDGMAGPHRNTTVLFLGSNDGTVLKVLP--PGGQSLGPEPIILEEIDA 472

  Fly   547 SPH-----------SEPIREMTLSHKTGSLYVATDHQVKQIDIAMCARRYDSCFR-CVS--DPYC 597
            ..|           :..|..:.|..:...|:||....:..:.::.|| |:.:|.| |::  ||||
  Rat   473 YSHARCSGKRSPRAARRIIGLELDTEGHRLFVAFPGCIVYLSLSRCA-RHGACQRSCLASLDPYC 536

  Fly   598 GWDK 601
            ||.:
  Rat   537 GWHR 540

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema2b	NP_001261024.1	Sema_2A	120..579	CDD:200499	158/494 (32%)
		Ig	632..720	CDD:299845
Sema6c	NP_059004.1	Sema	52..516	CDD:417757	159/503 (32%)
		PSI	517..>538	CDD:396154	10/21 (48%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	555..624
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	685..725
		PHA03307	730..>956	CDD:223039
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	745..792
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	806..960

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3611
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11036
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910