Protein Alignment Sema2b and Sema3g

DIOPT Version :9

• Sequence 1: NP_001261024.1
• Gene: Sema2b / 246538
• FlyBaseID: FBgn0264273
• Length: 824
• Species: Drosophila melanogaster
• Sequence 2: NP_001020550.1
• Gene: Sema3g / 218877
• MGIID: 3041242
• Length: 780
• Species: Mus musculus
• Alignment Length: 644
• Identity: 190/644 - (29%)
• Similarity: 279/644 - (43%)
• Gaps: 104/644 - (16%)

  Fly   118 GPLHYKTFYMDERNNALYVGAMDRIFRLNLRNISQSICERDVLILEPTGSDILNCVSKGKREKVE 182
            |.|..:..|:||..:.|::|:.|.::.|.|......  .|:||.|...|..: .||.|||....|
Mouse    54 GSLDLQVMYLDEYRDRLFLGSRDALYSLRLDQAWPD--PREVLWLPQPGQKV-ECVRKGKDPLTE 115

  Fly   183 CRNHIRVIQPMNFNGQKLYVCGTNAHNPKDYVINANLTHLPRSQYV-----PGIGLGIGKCPYDP 242
            |.|.:||:||  .|...|..|||.|..|    |...:|...|.::|     ..:..|.|:||::|
Mouse   116 CANFVRVLQP--HNRTHLLACGTGAFQP----ICTFITVGHRGEHVLRLDASSVENGRGRCPHEP 174

  Fly   243 ADNSTAVYVENGNPFGLPALYAGTNAEFTKADSVIFRSDLYNLTNGRKEANFKRTVKYDS--KLL 305
            :....:.:|..       .||.|..|:|...:::||||      .|.:.|     ::.||  .||
Mouse   175 SRPFASTFVGG-------ELYTGLTADFLGREAMIFRS------GGPRPA-----LRSDSDQSLL 221

  Fly   306 DKPNFVGSFEI-------GEFVYFFFREHAVEYI-NCGKAVYSRVARVCKNDRGGKYMISQNWAT 362
            .:|.||.:..|       .:.|||||.|...... ..|....|||.|||.||.||:.::...|:|
Mouse   222 HEPRFVMAARIPDNSDRDDDKVYFFFSETVPSPDGGPGHVTISRVGRVCVNDAGGQRVLVNKWST 286

  Fly   363 YLKARMNCSISSE--FPFYFNEIQSVYKM---PTDDTKFYATFTTNTNGLIGSAVCSYDIRDINA 422
            :||||:.||:...  ...:|::::.|:.:   .....:.||.|:|.:....|.|||.|.:.||..
Mouse   287 FLKARLVCSVPGPGGAETHFDQLEDVFLLWPKAGKSLEVYALFSTVSAVFQGFAVCVYHMVDIWE 351

  Fly   423 AFDGKFKEQATSNSAWLPVLNSKVPEPRPGTC-----------HNDTATLPDSVLNFIRKHPLMD 476
            .|:|.|..:......|.| ...|||.||||.|           ...|...||.||.|:|.||||.
Mouse   352 VFNGPFAHRDGPQHQWGP-YGGKVPFPRPGVCPSKMTAQPGRPFGSTKDYPDEVLQFVRDHPLMF 415

  Fly   477 KAVDHEFGNPVFFKRDVI--LTKLVVDKIRIDKLNQEFLVYFVATTSGHIYKIVQFMHYGQRHSN 539
            :.|....|.||..|..:.  |.::|||  |::..:..:.|.|:.|.||.:.|::.....|.....
Mouse   416 QPVRPRRGRPVLVKTHLAQRLRQIVVD--RVEAEDGTYDVIFLGTDSGSVLKVIALQGGGLTEPE 478

  Fly   540 LVDIFEASPHS--EPIREMTLSHKTGSLYVATDHQVKQIDIAMCARRYDSCFRC--VSDPYCGWD 600
            .|.:.|.....  .||.||.:|.|..:|||.:...|.::.:..|.....:|..|  ..||||.||
Mouse   479 EVVLEELQVFKVPTPITEMEISVKRQTLYVGSPLGVARLQLHQCETYGSACAECCLARDPYCAWD 543

  Fly   601 KDVNACRPYQ----------------------LGLLQDVANETSGICDTSVLRKKVTSSYGQTLH 643
            .  .||..|:                      ||..|......||:. |.|...:..|::
Mouse   544 G--TACARYRPSSGKRRFRRQDIRHGNPAVQCLGQGQSQNKAASGLM-TRVFGTEHNSTF----- 600

  Fly   644 LSCFVKMPEVLRKKQTRWY-HHSTEKGRYEVRYTPTKYIDTNEGGLVLLAVNEGDGGRY 701
            |.|..|.|:.    ..||: ....:||..:|: |..:.:.|.: ||:...::..|.|.|
Mouse   601 LECLPKSPQA----AVRWFLQRPGDKGTDQVK-TDERVVQTAQ-GLLFRRLSRHDAGNY 653

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema2b	NP_001261024.1	Sema_2A	120..579	CDD:200499	153/493 (31%)
		Ig	632..720	CDD:299845	17/71 (24%)
Sema3g	NP_001020550.1	Sema	49..522	CDD:301699	154/497 (31%)
		PSI	521..567	CDD:214655	12/47 (26%)
		Ig_Semaphorin_classIII	591..676	CDD:143279	18/74 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3611
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11036
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.910