Protein Alignment Sema2b and Sema3f

DIOPT Version :9

• Sequence 1: NP_001261024.1
• Gene: Sema2b / 246538
• FlyBaseID: FBgn0264273
• Length: 824
• Species: Drosophila melanogaster
• Sequence 2: XP_017168715.1
• Gene: Sema3f / 20350
• MGIID: 1096347
• Length: 820
• Species: Mus musculus
• Alignment Length: 655
• Identity: 200/655 - (30%)
• Similarity: 291/655 - (44%)
• Gaps: 125/655 - (19%)

  Fly   111 HVQDFSCGPLHYKTFYMDERNNALYVGAMDRIFRLNLRNISQSICERDVLILEPTGSD--ILNCV 173
            |..:|......|:....||.::.:|||:.|.:..|:|.:|:     |:.||:....|.  |..|:
Mouse    46 HFFNFLLNTTDYRILLKDEDHDRMYVGSKDYVLSLDLHDIN-----REPLIIHWAASPQRIEECI 105

  Fly   174 SKGKREKVECRNHIRVIQPMNFNGQKLYVCGTNAHNPKDYVINAN-------LTHL--------- 222
            ..||....||.|.:|:|||  :|...||||||.|:||....:|..       .|.:
Mouse   106 LSGKDGNGECGNFVRLIQP--WNRTHLYVCGTGAYNPMCTYVNRGRRAQALPWTQMQVVRGRGSR 168

  Fly   223 ------------PRSQYV-----PGIGLGIGKCPYDP-ADNSTAVYVENGNPFGLPALYAGTNAE 269
                        ||..|:     ..:..|.||||||| .|.::|:..|.        ||||...:
Mouse   169 ATDGADRPTPTAPRQDYIFYLEPEKLESGKGKCPYDPKLDTASALINEE--------LYAGVYID 225

  Fly   270 FTKADSVIFRSDLYNLTNGRKEANFKRTVKYDSKLLDKPNFVGSFEI-------GEFVYFFFREH 327
            |...|:.|||      |.|::.|  .||.:|:|:.|:.|:|:.:..|       .:.:||||||.
Mouse   226 FMGTDAAIFR------TLGKQTA--MRTDQYNSRWLNDPSFIHAELIPDSAERNDDKLYFFFRER 282

  Fly   328 AVEYINCGKAVYSRVARVCKNDRGGKYMISQNWATYLKARMNCSISSE--FPFYFNEIQSVYKMP 390
            :.|... ..|||:|:.|:|.||.||...:...|:|:||||:.||:..|  ...:|:|:|.|:...
Mouse   283 SAEAPQ-NPAVYARIGRICLNDDGGHCCLVNKWSTFLKARLVCSVPGEDGIETHFDELQDVFVQQ 346

  Fly   391 TDDTK---FYATFTTNTNGLIGSAVCSYDIRDINAAFDGKFKEQATSNSAWLPVLNSKVPEPRPG 452
            |.|.:   .||.||::.:...|||||.|.:.||...|:|.|..:...|..|:| .:.|:|.||||
Mouse   347 TQDVRNPVIYAVFTSSGSVFRGSAVCVYSMADIRMVFNGPFAHKEGPNYQWMP-FSGKMPYPRPG 410

  Fly   453 TCHNDTAT--------LPDSVLNFIRKHPLMDKAVDHEFGNPVFFKRDV--ILTKLVVDKIRIDK 507
            ||...|.|        .||.|:||:|.||||.:||......|:..:...  .||.:.||  ::|.
Mouse   411 TCPGGTFTPSMKSTKDYPDEVINFMRTHPLMYQAVYPLQRRPLVVRTGAPYRLTTVAVD--QVDA 473

  Fly   508 LNQEFLVYFVATTSGHIYKIVQFMHYGQRHSNL----VDIFEASPHSEPIREMTLSHKTGSLYVA 568
            .:..:.|.|:.|..|.:.|::......|....|    |::|:   ...|::.||:|.|...||||
Mouse   474 ADGRYEVLFLGTDRGTVQKVIVLPKDDQEVEELMLEEVEVFK---EPAPVKTMTISSKRQQLYVA 535

  Fly   569 TDHQVKQIDIAMCARRYDSCFRC--VSDPYCGWDKDVNACRPY-----QLGLLQDVAN-----ET 621
            :...|..:.:..|.....:|..|  ..||||.||.  .||..|     :....|||.:     :.
Mouse   536 SAVGVTHLSLHRCQAYGAACADCCLARDPYCAWDG--QACSRYTASSKRRSRRQDVRHGNPIRQC 598

  Fly   622 SGICDTSVLRKKVTSSY-----GQTLHLSCFVKMPEVLRKKQTRW-YHHSTEKGRYEVRY----- 675
            .|.  .|...|....|.     |....|.|..:.|:.    ..:| :.......|.||..
Mouse   599 RGF--NSNANKNAVESVQYGVAGSAAFLECQPRSPQA----TVKWLFQRDPSDRRREVSSCVLSP 657

  Fly   676 --TPT 678
              |||
Mouse   658 PPTPT 662

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema2b	NP_001261024.1	Sema_2A	120..579	CDD:200499	168/520 (32%)
		Ig	632..720	CDD:299845	13/60 (22%)
Sema3f	XP_017168715.1	Sema_3F	48..548	CDD:200515	169/529 (32%)
		PSI	547..584	CDD:214655	12/38 (32%)
		Ig	609..>650	CDD:386229	7/44 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	51	1.000	Domainoid score	I11477
eggNOG	1	0.900	-	-		E1_KOG3611
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11036
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X596
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.910