Protein Alignment Sema2b and LOC1277221

DIOPT Version :10

• Sequence 1: NP_001261024.1
• Gene: Sema2b / 246538
• FlyBaseID: FBgn0264273
• Length: 824
• Species: Drosophila melanogaster
• Sequence 2: XP_061506710.1
• Gene: LOC1277221 / 1277221
• VectorBaseID: AGAMI1_011129
• Length: 741
• Species: Anopheles gambiae
• Alignment Length: 726
• Identity: 494/726 - (68%)
• Similarity: 599/726 - (82%)
• Gaps: 20/726 - (2%)

  Fly    67 LVLVAQTVHVEYAR---ADYENTWNLYYEPPCC-TGSS--------AAHHLRHHKEHVQDFSCGP 119
            |||....|.::..|   .|||||||.|||.||| :|.|        ..||||||::||::|.||.
Mosquito    19 LVLTVAFVLLQLLRPGAGDYENTWNFYYEQPCCGSGQSNVGGISINGQHHLRHHRDHVREFQCGK 83

  Fly   120 LHYKTFYMDERNNALYVGAMDRIFRLNLRNISQSICERDVLILEPTGSDILNCVSKGKREKVECR 184
            .:|:|||:||..:.||||||||:|:|||:|:|.:.||||.::|:||.|||.|||||||.|..:|:
Mosquito    84 FYYRTFYLDEERDTLYVGAMDRVFKLNLKNVSMTSCERDTIVLDPTSSDIRNCVSKGKSEMFDCK 148

  Fly   185 NHIRVIQPMNFNGQKLYVCGTNAHNPKDYVINANLTHLPRSQYVPGIGLGIGKCPYDPADNSTAV 249
            |||||||||: :|.:||:||||||||||.||.:||||||||:|||||||||.||||||.|||||:
Mosquito   149 NHIRVIQPMD-SGNRLYICGTNAHNPKDLVIYSNLTHLPRSEYVPGIGLGIAKCPYDPYDNSTAI 212

  Fly   250 YVENGNPFGLPALYAGTNAEFTKADSVIFRSDLYNLTNGRKEANFKRTVKYDSKLLDKPNFVGSF 314
            |||.|||..|||||:||||||||||:||||:||||:|.|:|..|||||:|||||.||||||||||
Mosquito   213 YVEQGNPGDLPALYSGTNAEFTKADTVIFRTDLYNMTTGKKVFNFKRTLKYDSKWLDKPNFVGSF 277

  Fly   315 EIGEFVYFFFREHAVEYINCGKAVYSRVARVCKNDRGGKYMISQNWATYLKARMNCSISSEFPFY 379
            :|||.|||||||.||||||||||||||||||||.|.|||.:::||||||||||:|||||.|||||
Mosquito   278 DIGEHVYFFFRETAVEYINCGKAVYSRVARVCKKDTGGKNILNQNWATYLKARINCSISGEFPFY 342

  Fly   380 FNEIQSVYKMPTDDTKFYATFTTNTNGLIGSAVCSYDIRDINAAFDGKFKEQATSNSAWLPVLNS 444
            |||||.||::|||.|||||||||:||||:||||||:||.:|:.||.|||||||:|||||||||||
Mosquito   343 FNEIQDVYQLPTDKTKFYATFTTSTNGLVGSAVCSFDINEIHGAFAGKFKEQASSNSAWLPVLNS 407

  Fly   445 KVPEPRPGTCHNDTATLPDSVLNFIRKHPLMDKAVDHEFGNPVFFKRDVILTKLVVDKIRIDKLN 509
            |:||||||||.|||:|||||||||||.||||||||:||..|||::|||::.||||||||:|:.|:
Mosquito   408 KIPEPRPGTCVNDTSTLPDSVLNFIRSHPLMDKAVNHEHNNPVYYKRDLVFTKLVVDKIKIEILS 472

  Fly   510 QEFLVYFVATTSGHIYKIVQFMHYGQRHSNLVDIFEASPHSEPIREMTLSHKTGSLYVATDHQVK 574
            ||:.|:::.|.:|.||||||::..|:..|.|:||||.: .:|.|:.|.||.|..|||||||:::|
Mosquito   473 QEYTVFYIGTNAGRIYKIVQYLRNGESKSKLLDIFEIA-QNEAIQVMELSQKRKSLYVATDYRIK 536

  Fly   575 QIDIAMCARRYDSCFRCVSDPYCGWDKDVNACRPYQLGLLQDVANETSGICDTSVLRKKVTSSYG 639
            |||:|||.||||:|||||.|||||||||.:.|:||:.||||||.|||..|||||||:||:..:||
Mosquito   537 QIDLAMCNRRYDNCFRCVKDPYCGWDKDTSTCKPYEPGLLQDVGNETYDICDTSVLKKKIIVTYG 601

  Fly   640 QTLHLSCFVKMPEVLRKKQTRWYHHSTEKGRYEVRYTPTKYIDTNEGGLVLLAVNEGDGGRYDSY 704
            |::||.||||:||:|:.:...|||||.||||||::|.|||||:|.|.|||:::|||.||||||.:
Mosquito   602 QSVHLGCFVKIPEILKDQTVTWYHHSKEKGRYEIKYNPTKYIETTERGLVVISVNEADGGRYDCH 666

  Fly   705 LDGTLLCSYGVTVDAHRCSPPSQKQDYQKIYSHWCNEFEKYKSAMKQWQAKQEQCGLKDKTGPIS 769
            |.|:|||||.:|||||||:||::..|||||||.||:||||||||||.|:.||.||..:      :
Mosquito   667 LGGSLLCSYNITVDAHRCTPPNKTNDYQKIYSDWCHEFEKYKSAMKTWEKKQAQCSRQ------N 725

  Fly   770 SNGKHVNDVFS 780
            .:.:|.||||:
Mosquito   726 YSNQHPNDVFA 736

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema2b	NP_001261024.1	Sema_2A	120..579	CDD:200499	333/458 (73%)
		PSI	583..>606	CDD:396154	18/22 (82%)
		Ig	632..724	CDD:472250	59/91 (65%)
		Ig strand B	642..646	CDD:409353	2/3 (67%)
		Ig strand C	658..662	CDD:409353	0/3 (0%)
		Ig strand E	686..690	CDD:409353	2/3 (67%)
		Ig strand F	700..705	CDD:409353	3/4 (75%)
		Ig strand G	717..720	CDD:409353	2/2 (100%)
LOC1277221	XP_061506710.1	None