Protein Alignment Sema2b and sema6a

DIOPT Version :9

• Sequence 1: NP_001261024.1
• Gene: Sema2b / 246538
• FlyBaseID: FBgn0264273
• Length: 824
• Species: Drosophila melanogaster
• Sequence 2: XP_017946194.2
• Gene: sema6a / 100493034
• XenbaseID: XB-GENE-980417
• Length: 1037
• Species: Xenopus tropicalis
• Alignment Length: 714
• Identity: 215/714 - (30%)
• Similarity: 319/714 - (44%)
• Gaps: 146/714 - (20%)

  Fly    76 VEYARADYE--------NTWNLYYEPPCCTGSSAAHH-LRHHKEHVQDFSCGPLHYKTFYMDERN 131
            :::|||.:.        :..|...:.|...|.....: .:.||..:|....            .|
 Frog    13 LQFARAGFPEDSEPISISHGNYTKQYPVFVGHKPGRNSTQRHKMDIQQIVI------------MN 65

  Fly   132 NALYVGAMDRIFRLNLR-NISQSICERDVLILEPTGSDILNCVSKGKREKVECRNHIRVIQPMNF 195
            ..||:.|.|.|:.::|. :.::.|.....|..:...||:..|..||| .|.||.|.|:|:  :..
 Frog    66 RTLYIAARDHIYTVDLETSYTEEIFFSKKLTWKSKQSDVDTCRMKGK-HKDECHNFIKVL--LKR 127

  Fly   196 NGQKLYVCGTNAHNPKDYVINANLTHLPRSQYVPGIGLGIGKCPYDPADNSTAVYVENGNPFGLP 260
            :...|:||||||.||     :.....:...:::.....|:.:||||....:.|::.:.
 Frog   128 DEDTLFVCGTNAFNP-----SCRYYKMDTLEFLDEEISGMARCPYDAKHANVALFADG------- 180

  Fly   261 ALYAGTNAEFTKADSVIFRSDLYNLTNGRKEANFKRTVKYDSKLLDKPNFVGSFEIGEFVYFFFR 325
            .||:.|..:|...|:||:||    |.:|..    .||||||||.|.:|.||.:.:.|:.:|||:|
 Frog   181 KLYSATVTDFLAIDAVIYRS----LGDGPT----LRTVKYDSKWLKEPYFVHAVDYGDLIYFFYR 237

  Fly   326 EHAVEYINCGKAVYSRVARVCKNDRGG-KYMISQNWATYLKARMNCSISSEFPFYFNEIQSVYKM 389
            |.||||.:.||.|:.|||:|||||.|| :.::.:.|.::||||:|||:..:..||||.:|:|
 Frog   238 EIAVEYNSMGKVVFPRVAQVCKNDMGGSQRVLEKQWTSFLKARLNCSVPGDSHFYFNILQAV--- 299

  Fly   390 PTDDTKF------YATFTTNTNGLIGSAVCSYDIRDINAAFDGKFKEQATSNSAWLPVLNSKVPE 448
             ||....      .|||:|..|.:.|||||:||:.||.:.|.|:||||.:.:|.|.||.:.:||:
 Frog   300 -TDVIHINGRDVVLATFSTPYNSIPGSAVCAYDMADIASVFTGRFKEQKSPDSTWTPVPDERVPK 363

  Fly   449 PRPGTCHNDTAT--------LPDSVLNFIRKHPLMDKAVDHEFGNPVFFKRDV--ILTKLVVDKI 503
            ||||.|......        |||..||||:.|||||:||......|:|.:..|  .|||:.||..
 Frog   364 PRPGCCAGSATVERITKSNELPDDTLNFIKTHPLMDEAVPSVINRPLFLRTMVRYRLTKIAVDTA 428

  Fly   504 RIDKLNQEFLVYFVATTSGHIYKIVQFMHYGQRHSNLVDIFEASPHS-----------EPIREMT 557
            .  ...|...|.|:.:..|.:.|.:....|....|:.:.:.|.:.::           :.|..|.
 Frog   429 A--GPYQNHTVVFLGSERGIVLKFLARTGYSGFLSDSLFLEEMNVYNSEKCSFDGAEDKRILGMQ 491

  Fly   558 LSHKTGSLYVATDHQVKQIDIAMCARRYDSCFRCVS--DPYCGWDKDVNACR--------PYQLG 612
            |.....:||||....|..:.:|.|.|.......|::  ||||.|.::...|.        |::
 Frog   492 LDKHNNALYVAFSTCVVSVPLARCDRHTKCKKTCIASRDPYCVWLREGGTCSQLLTGTKVPFE-- 554

  Fly   613 LLQDVAN-ETSGI--CDTSVLRKKVTSSYGQTLHLSCFVKMP----EVLRKKQTRWYHHSTEKGR 670
              |||.: .|.|:  |..|.:.            |:.|...|    |:        |:|:.
 Frog   555 --QDVEHGNTDGLGDCQNSFVA------------LNEFATSPPPDQEI--------YYHTV---- 593

  Fly   671 YEVRYTP--TKYIDTNEGGLVLLAVNEGDGGRYD--SYLDGTLLCSYGVTVDAHRCSPPSQKQD 730
                |.|  |.|...:||              ||  |.||...:.......|.|........||
 Frog   594 ----YDPSTTSYSRVHEG--------------YDRGSMLDWKDIYDSSENTDPHVADSFHNHQD 639

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema2b	NP_001261024.1	Sema_2A	120..579	CDD:200499	167/487 (34%)
		Ig	632..720	CDD:299845	18/95 (19%)
sema6a	XP_017946194.2	Sema	48..513	CDD:417757	170/505 (34%)
		PSI	514..>544	CDD:396154	9/29 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	283	1.000	Inparanoid score	I2804
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.050