Protein Alignment Sema2b and sema4c

DIOPT Version :9

• Sequence 1: NP_001261024.1
• Gene: Sema2b / 246538
• FlyBaseID: FBgn0264273
• Length: 824
• Species: Drosophila melanogaster
• Sequence 2: XP_004912631.1
• Gene: sema4c / 100486259
• XenbaseID: XB-GENE-856519
• Length: 837
• Species: Xenopus tropicalis
• Alignment Length: 670
• Identity: 205/670 - (30%)
• Similarity: 313/670 - (46%)
• Gaps: 108/670 - (16%)

  Fly   105 LRHHKEHV--QDFSCGPLHYKTFYMDERNNALYVGAMDRIFRLNLRNISQSICERDVLILEPTGS 167
            :|:|...|  |.:..|.....|..:||...||||||.:.||.|:|.||.:.:  |..:|.:....
 Frog    30 VRYHGVSVVRQSWRNGVSQVMTLTLDEDRGALYVGAREVIFSLDLSNIGKEL--RPPIIWQAPAD 92

  Fly   168 DILNCVSKGKREKVECRNHIRVIQPMNFNGQKLYVCGTNAHNPK-------DYVINA-NLTHLPR 224
            ....|..|||..:.||.|:||.::  .:|...|..|||.|..||       .:.::| ||..
 Frog    93 KKAECAQKGKSNQTECFNYIRFLE--EYNQTHLITCGTYAFQPKCAYIALSGFTLDADNLEE--- 152

  Fly   225 SQYVPGIGLGIGKCPYDPADNSTAVYVENGNPFGLPALYAGTNAEFTKADSVIFRSDLYNLTNGR 289
                     |.||.|||||...|.:.::.       |||:.|...|...:.||.|.        .
 Frog   153 ---------GKGKVPYDPAKGYTGLILDG-------ALYSATMNNFLGTEPVIMRI--------V 193

  Fly   290 KEANFKRTVKYDSKLLDKPNFVGS--------FEIG--EFVYFFFREHAVEYINCGKAVYSRVAR 344
            .:.|..:| :|.:..|::||||.|        .|||  :.:|:||.|.|:||....:.|.|||||
 Frog   194 GQHNIMKT-EYLASWLNEPNFVSSAHMPESVGSEIGDDDKIYYFFTERALEYDCSSEQVVSRVAR 257

  Fly   345 VCKNDRGGKYMISQNWATYLKARMNCSISSEFPFYFNEIQSVYKMPTDD---TKFYATFTTNTNG 406
            :||.|.||...:.:.|.::||||:.||| .|....||.::||:|:..::   |:|:|.|......
 Frog   258 ICKGDLGGARTLQRKWTSFLKARLLCSI-PELQLNFNLLKSVFKLEAEEWRSTQFFAAFQARWGD 321

  Fly   407 LIGSAVCSYDIRDINAAFDGKFKEQATSNSAWLPVLNSKVPEPRPGTC----HND-----TATLP 462
            ...||||.|.|.||...|||.:||....:..|....:| ||.||||:|    |.:     :..||
 Frog   322 SPVSAVCQYSIHDIQKVFDGPYKEYREQSQKWGRYSDS-VPSPRPGSCITNWHRNHGVYSSLELP 385

  Fly   463 DSVLNFIRKHPLMDKAVDHEFGNPVFFKRDVILTKLVVDK-IRIDKLNQEFLVYFVATTSGHIYK 526
            |:.|||::||||||..|....|.|:..:|.:..|.:.|.: :.:||  :.:.|.|:.|.:|.:.|
 Frog   386 DNTLNFVKKHPLMDDTVMPSQGRPLLVRRGINFTTIAVQRTLGLDK--EPYDVLFIGTDNGWVNK 448

  Fly   527 IVQF---MHYGQRHSNLVDIFEASPHSEPIREMTLSHKTGSLYVATDHQVKQIDIAMCARRYDSC 588
            .|.|   :|       :::..:....|.|:..:.:|.:...|||.:...:.|:..|.|: :|.||
 Frog   449 AVSFGSTVH-------IIEELQVFDKSYPVNSLAVSSRKSLLYVGSQSGLVQLPFADCS-KYRSC 505

  Fly   589 FRCV--SDPYCGWDKDVNAC----RPYQLGLLQDVANETSGICDTSVLR-------KKVTSSYGQ 640
            ..|:  .||||.|:.:::.|    ..::..||||:.:..:.:|:...:.       |.:|...|.
 Frog   506 ADCILARDPYCAWNVNISRCVRADEQHRSVLLQDIQDSDTSVCEVQNMNAAVRYFSKNITIGIGT 570

  Fly   641 TLHLSCFV--KMPEVLRKKQTRWYHHSTEKGRYEVRYTPTKYIDTNEGGLVLLAVNEGDGGRYDS 703
            .:.|.|.:  .:.|.:      |.....:.|..:   ..:...|.....||:|.|.....|.|..
 Frog   571 NVVLPCQLSSNLAEPI------WTFDGQDMGSDQ---DDSVLFDATLQALVILGVGTHHSGSYVC 626

  Fly   704 YLD--GTLLCS--YGVTVDA 719
            :.:  ||.|.|  |.:||.|
 Frog   627 FSEEQGTRLTSENYQLTVVA 646

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema2b	NP_001261024.1	Sema_2A	120..579	CDD:200499	160/492 (33%)
		Ig	632..720	CDD:299845	23/94 (24%)
sema4c	XP_004912631.1	Sema_4C	38..497	CDD:200519	162/501 (32%)
		PSI	498..>530	CDD:214655	11/32 (34%)
		Ig	562..647	CDD:386229	23/94 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11036
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010