Protein Alignment Sema2b and sema3b

DIOPT Version :10

• Sequence 1: NP_001261024.1
• Gene: Sema2b / 246538
• FlyBaseID: FBgn0264273
• Length: 824
• Species: Drosophila melanogaster
• Sequence 2: NP_001120908.1
• Gene: sema3b / 100151737
• XenbaseID: XB-GENE-921561
• Length: 773
• Species: Xenopus tropicalis
• Alignment Length: 773
• Identity: 214/773 - (27%)
• Similarity: 342/773 - (44%)
• Gaps: 143/773 - (18%)

  Fly    54 KGKHRLCSLSALLLV-LVAQTVHVEYARADYENTWNLY------YEPPCCTGSSAAHHLRHHKEH 111
            |.:..|.||..||.. |:.........:..|::..:|:      .|..||
 Frog     2 KLQRSLLSLCLLLYFGLIGSNKVTPRLKLSYQDLMSLHGLRTFTLERSCC--------------- 51

  Fly   112 VQDFSCGPLHYKTFYMDERNNALYVGAMDRIFRLNLRNISQSICERDVLILEPTGSDIL-NCVSK 175
                      |...::||....|:||..:.:..|:|.|||    ::::.|..|...:.. .|...
 Frog    52 ----------YDALFLDEERGRLFVGGKNYLMSLSLDNIS----KQELAIHWPAPVEWREECNWA 102

  Fly   176 GKREKVECRNHIRVIQPMNFNGQKLYVCGTNAHNP-----------KDYVINANLTHLPRSQYVP 229
            ||...|:|.|:::::||  :|...|:.|||.|.:|           .|.|...:|..:..
 Frog   103 GKDINVDCMNYVKILQP--YNRTHLFTCGTGAFHPTCGFVHVGQRTDDTVFKMDLRRMED----- 160

  Fly   230 GIGLGIGKCPYDPADNSTAVYVENGNPFGLPALYAGTNAEFTKADSVIFRSDLYNLTNGRKEANF 294
                |.|:|||||...:.||.|.:       .||:|...:....|..||||      .||:..
 Frog   161 ----GKGRCPYDPKHIAAAVLVGD-------ELYSGVATDLMGRDFTIFRS------LGRRPP-- 206

  Fly   295 KRTVKYDSKLLDKPNFVGSFEIGEF-------VYFFFREHAVEYINCGKAVYSRVARVCKNDRGG 352
            .||.::||:.|::|.||..|.|.|.       :||||:|..||.....|..|:|:.::|:||.||
 Frog   207 LRTEQHDSRWLNEPKFVKVFWIPESENPDDDKIYFFFKETPVEGAGGVKQSYARIGQICRNDLGG 271

  Fly   353 KYMISQNWATYLKARMNCSI-SSEF--PFYFNEIQSVYKMPTDDTK---FYATFTTNTNGLIGSA 411
            :..:...|.|:||||:.||: .:|.  ..:|:|::.|:.:.|.|.:   .||.|:|:::...|||
 Frog   272 QRSLVNKWTTFLKARLVCSVPGNEIGGDTHFDELRDVFLLQTRDRRNPLIYALFSTSSSVFRGSA 336

  Fly   412 VCSYDIRDINAAFDGKFKEQATSNSAWLPVLNSKVPEPRPGTC-------HNDTATLPDSVLNFI 469
            :|.|.:.|:..||.|.|..:...|..|:. ...|||.||||.|       ...|.:.||.||.|.
 Frog   337 ICVYTMNDVRRAFLGPFAHKEGPNYQWVS-YQGKVPYPRPGMCPSKTFGSFESTKSFPDDVLQFA 400

  Fly   470 RKHPLMDKAVDHEFGNPVFFKR--DVILTKLVVDKIRIDKLNQEFLVYFVATTSGHIYKIVQFMH 532
            |.||||...|....|.|||.:.  |:..|:|.||  |:...:.|:.|.|:.|..|.:.|::....
 Frog   401 RNHPLMFNPVVPGSGRPVFLRSHGDLSFTQLAVD--RVAAADGEYDVMFIGTDVGSVLKVISVPK 463

  Fly   533 YGQRHSNLVDIFEAS--PHSEPIREMTLSHKTGSLYVATDHQVKQIDIAMCARRYDSCFRC--VS 593
            ....|...|.:.|..  .::.||..|.:|.|...:||.:...:.|:.:..|.....:|..|  ..
 Frog   464 QSWHHVEQVVLEELQVFKNASPITTMQISSKRQQIYVGSASGISQLPLHRCGIYGKACAECCLAR 528

  Fly   594 DPYCGWDKDVNACRPY-----QLGLLQDVAN-ETSGICD-----TSVLRKKVTSSYGQTLHLSCF 647
            ||||.||.  .:|..:     :....|||.| :.:.:|.     .||..|::....|.::.|.|
 Frog   529 DPYCAWDG--ASCTRFLPNTKRRSRRQDVRNGDPNTLCSGEQQRFSVQEKRLLGVEGSSIFLEC- 590

  Fly   648 VKMPEVLRKKQTRWYHHSTEKGRYEVRYTPTKYIDTNEGGLVLLAVNEGDGGRYDSYLDGTLLC- 711
              :|:.||.:.|..|..:.|..|.||:: ..:.:.|:. |:|:..|...|.        ||.:|
 Frog   591 --LPKSLRAQVTWTYQKAPESSRTEVQF-DERVLQTDR-GIVVRNVLRRDA--------GTFICY 643

  Fly   712 --SYGVTVDAHRCS----PPSQKQDY---QKI-YSHWCNEFEKYKSAMKQWQAKQEQC 759
              .:|.|....|..    |.|:.:::   |:: ::.|..:|.:   .::|..:.::.|
 Frog   644 SSEHGFTQTLLRLHLEVIPSSRTEEHLGLQRVPHNRWYQDFMR---LVQQPGSVEQMC 698

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema2b	NP_001261024.1	Sema_2A	120..579	CDD:200499	154/494 (31%)
		PSI	583..>606	CDD:396154	8/24 (33%)
		Ig	632..724	CDD:472250	24/98 (24%)
		Ig strand B	642..646	CDD:409353	1/3 (33%)
		Ig strand C	658..662	CDD:409353	1/3 (33%)
		Ig strand E	686..690	CDD:409353	1/3 (33%)
		Ig strand F	700..705	CDD:409353	0/4 (0%)
		Ig strand G	717..720	CDD:409353	0/2 (0%)
sema3b	NP_001120908.1	Sema_3B	43..514	CDD:200511	157/528 (30%)
		PSI	513..550	CDD:214655	10/38 (26%)
		Ig	572..663	CDD:472250	26/103 (25%)
		Ig strand B	586..590	CDD:409353	1/3 (33%)
		Ig strand C	598..602	CDD:409353	1/3 (33%)
		Ig strand E	625..629	CDD:409353	1/4 (25%)
		Ig strand F	639..644	CDD:409353	2/4 (50%)
		Ig strand G	656..659	CDD:409353	0/2 (0%)