Protein Alignment Sema2b and sema4d

DIOPT Version :9

• Sequence 1: NP_001261024.1
• Gene: Sema2b / 246538
• FlyBaseID: FBgn0264273
• Length: 824
• Species: Drosophila melanogaster
• Sequence 2: XP_012814281.1
• Gene: sema4d / 100038178
• XenbaseID: XB-GENE-492763
• Length: 852
• Species: Xenopus tropicalis
• Alignment Length: 690
• Identity: 212/690 - (30%)
• Similarity: 329/690 - (47%)
• Gaps: 121/690 - (17%)

  Fly    61 SLSALLLVLVAQTVHVEYARADYENTWNLYYEPPCCTGSSAAHHLRHHKEHVQDFSCGPLHYKTF 125
            :.:||.|||.......|:..|. ..||:|           ...:|.|.  ||...|    :|.|.
 Frog     6 AFNALYLVLCTAFGAAEFGPAP-RITWHL-----------KETNLMHF--HVSGIS----NYSTL 52

  Fly   126 YMDERNNALYVGAMDRIFRLNLRNISQSICERDVLILEPTGSDILNCVSKGKREKVECRNHIRVI 190
            .:.|..:.|||||.:.||.::..|:::.:.|....:.:...::   |..|||.::.||.|:||||
 Frog    53 LLSEEKDVLYVGAREAIFAVSSLNVAEKLHEAYWKVSDEKNNE---CAWKGKSKQTECLNYIRVI 114

  Fly   191 QPMNFNGQKLYVCGTNAHNPK-DYVINANLTH---LPRSQYVPGIGLGIGKCPYDPADNSTAVYV 251
            ||:  |.:.||||||||..|. ||:   |||.   |.|::.      |.|:||:|||.:..:|.|
 Frog   115 QPL--NDKTLYVCGTNAFQPTCDYL---NLTDFRLLGRNED------GKGRCPFDPAQSYISVMV 168

  Fly   252 ENGNPFGLPALYAGTNAEFTKADSVIFRSDLYNLTNGRKEANFKRTVKYDSKLLDKPNFVGSFEI 316
            :.       .||:||:..|..::.:||          |..:..:...:|....|::|:||.:..|
 Frog   169 DG-------ELYSGTSFNFLGSEPIIF----------RHSSQSQLRTEYAVPWLNEPSFVYADVI 216

  Fly   317 ----------GEFVYFFFREHAVEYINCGKAVYSRVARVCKNDRGGKYMISQNWATYLKARMNCS 371
                      .:.|||||.|.:|||....|.:..|||||||.|:||...:.:.|.::|||::.|.
 Frog   217 RAPANNPEGDDDKVYFFFTEVSVEYEFFSKLLIPRVARVCKGDQGGLRTLQKKWTSFLKAKLICH 281

  Fly   372 ISSEFPFYFNEIQSVYKMPTDDT---KFYATFTTNTNGLIGSAVCSYDIRDINAAF-DGKFKEQA 432
             |||....||.:..|:.:...|:   |.|..||::.|.:..||||:|::..:...| .||:...|
 Frog   282 -SSENNLIFNVVSDVFILKHSDSSEPKIYGVFTSHLNNVGLSAVCAYNVSTVEEVFAKGKYMHSA 345

  Fly   433 T---SNSAWLPVLNSKVPEPRPGTCHNDTA---------TLPDSVLNFIRKHPLMDKAVDHEFGN 485
            |   ||:.|:. .|.:||:||||.|.|:.|         .|||..|.|::.|||||.:|......
 Frog   346 TVEQSNTKWVR-YNGEVPKPRPGACINNEARAMNYTSSLNLPDMTLQFVKDHPLMDDSVSPVGNK 409

  Fly   486 PVFFKRDVILTKLVVDKIR-IDKLNQEFLVYFVATTSGHIYKIVQFMHYGQRHSNLVDIFEASPH 549
            |....||||.|::|||::: :|  ...:.:.|::|..|.::|.|.    ......:::.....||
 Frog   410 PKLVLRDVIYTQIVVDRVKALD--GNSYDIMFLSTDKGILHKAVS----QDAEMRIIEEIVLFPH 468

  Fly   550 SEPIREMTLSHKTGS--LYVATDHQVKQIDIAMCARRYDSCFRCV--SDPYCGWDKDVNACRPYQ 610
            .:|::.:.||:|.|.  :|..::..|.|..:|.| .::.||..|:  .||||.|.....:|
 Frog   469 LQPVQTLLLSNKEGKRFIYAGSNTGVVQSPLAFC-EKFTSCKDCILTRDPYCAWHPVKRSC---- 528

  Fly   611 LGLLQDVANETSGI---------C-DTSVLRK--KVTSSYGQTLHLSCFVKMPEVLRKKQTRW-Y 662
            :.:|||...:.|.|         | |::.::|  |.|.....|:.|.|..|.    :.....| :
 Frog   529 VNILQDSTADGSLIQKLNGDASQCPDSAEIQKSMKHTVKSRSTVELKCSQKS----KLANLVWQF 589

  Fly   663 HHSTEKGRYEVRYTPTKYIDTNEGGLVLLAVNEGDGGRYD 702
            .:.|.|...      .|| ...|..||:..:.:.|.|.|:
 Frog   590 SNKTLKAEL------PKY-HLLEHALVIFNITDHDAGIYE 622

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema2b	NP_001261024.1	Sema_2A	120..579	CDD:200499	161/491 (33%)
		Ig	632..720	CDD:299845	18/74 (24%)
sema4d	XP_012814281.1	Sema_4D	30..500	CDD:200520	169/525 (32%)
		PSI	502..>529	CDD:214655	10/31 (32%)
		Ig	561..645	CDD:386229	17/73 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11036
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010