DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht12 and Chi3l1

DIOPT Version :9

Sequence 1:	NP_726022.1	Gene:	Cht12 / 246535	FlyBaseID:	FBgn0050293	Length:	470	Species:	Drosophila melanogaster
Sequence 2:	NP_001296749.1	Gene:	Chi3l1 / 89824	RGDID:	620874	Length:	391	Species:	Rattus norvegicus

Alignment Length:	390	Identity:	121/390 - (31%)
Similarity:	192/390 - (49%)	Gaps:	74/390 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 MIFLICGCIAKEYNVFCQYDLGSYYYKGRSQFFEWHLDSRLCTHLVLGSGIGVDGDSGELRITDK 75
            ::.|:..|.|  |.:.|.|...|.|.:|....|...||..||||::.                 .
  Rat    20 VLMLLQSCSA--YKLVCYYTNWSQYREGNGSCFPDALDHSLCTHIIY-----------------S 65

  Fly    76 ILLLEKDKLSSVKTMKWDSIK---------------KVMFTIGGWEEDSSSFSRMVASPKKRDNF 125
            ...:..:|||   |.:|:.:.               |.:.::|||...|..|||:|::.|.|..|
  Rat    66 FANISNNKLS---TSEWNDVTLYGMLNTLKTRNPRLKTLLSVGGWSFGSERFSRIVSNAKSRKTF 127

  Fly   126 YSSMLEFMFRWGFDGVQIDWRYPTLLGGHPDDRQNFVILLEELGLIFRK------NQLILMVAVL 184
            ..|:..|:..:||||:.:.|.||     .|.|:|:|..|::||...|.|      .:|:|..||.
  Rat   128 VQSVAPFLRTYGFDGLDLAWLYP-----GPKDKQHFTTLIKELKAEFTKEVQPGTEKLLLSAAVS 187

  Fly   185 GRRDNRILES-YNIPEIVNHSDFIHLMMHDEQDPYHLRLAYNAPLVGYEG----------SVTDS 238
            ..:..  |:| |::.:|..|.|||:||.:|....:.....:::||  :.|          :|...
  Rat   188 AGKVT--LDSGYDVAQIAQHLDFINLMTYDFHGTWRHTTGHHSPL--FRGQQDTGPDRFSNVDYG 248

  Fly   239 IMHWKRNGGAPEKLILGIPLFVRSFTMDRNQSTVGSACKG---PGRQTKQSHRPGFMTYNEWC-- 298
            :.:..|.|....||::|||.|.:|||:..:::.||:...|   |||.||:.   |.:.|.|.|
  Rat   249 VGYMLRLGAPTNKLVMGIPTFGKSFTLASSENQVGAPITGSGLPGRYTKEK---GTLAYYEICDF 310

  Fly   299 VQQSKWSRMFDQLAKVPYATRGDQWVSYENPRSIWAKMHLLQEHKLGGAMAWTIDVDDFRGR-CG 362
            ::.::..|:..|  :||:||:|:|||.|::|.|:..|:..|:..:|.|||.|.:|:|||||. ||
  Rat   311 LRGAEVHRILGQ--QVPFATKGNQWVGYDDPESVKNKVKYLKNKQLAGAMVWAVDLDDFRGSFCG 373

Fly 363 362
Rat 374 373

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht12	NP_726022.1	GH18_chitinase-like	25..375	CDD:299167	117/376 (31%)
		Glyco_hydro_18	47..355	CDD:279094	104/344 (30%)
		ChtBD2	394..438	CDD:214696
Chi3l1	NP_001296749.1	Glyco_18	31..365	CDD:214753	110/367 (30%)
Chi3l1	NP_001296749.1	GH18_chitolectin_chitotriosidase	32..388	CDD:119351	117/376 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166350379
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1289629at2759
OrthoFinder	1	1.000	-	-		FOG0000107
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X91
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.850