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Protein Alignment Cht12 and Chia1

DIOPT Version :9

Sequence 1:	NP_726022.1	Gene:	Cht12 / 246535	FlyBaseID:	FBgn0050293	Length:	470	Species:	Drosophila melanogaster
Sequence 2:	NP_075675.2	Gene:	Chia1 / 81600	MGIID:	1932052	Length:	473	Species:	Mus musculus

Alignment Length:	495	Identity:	132/495 - (26%)
Similarity:	215/495 - (43%)	Gaps:	93/495 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 MIMIFLICGC-------IAKEYNVFCQYDLGSYYYKGRSQFFEWHLDSRLCTHLVLG-SGIGVDG 65
            |..:.|:.|.       :...||:.|.:...:.|..|...|....::..|||||:.. :|:
Mouse     1 MAKLLLVTGLALLLNAQLGSAYNLICYFTNWAQYRPGLGSFKPDDINPCLCTHLIYAFAGM---- 61

  Fly    66 DSGELRITDKILLLEKDKLSSVKTMKWDSIK---------------KVMFTIGGWEEDSSSFSRM 115
                             :.:.:.|::|:.:.               |.:..||||...::.|:.|
Mouse    62 -----------------QNNEITTIEWNDVTLYKAFNDLKNRNSKLKTLLAIGGWNFGTAPFTTM 109

  Fly   116 VASPKKRDNFYSSMLEFMFRWGFDGVQIDWRYPTLLGGHPDDRQNFVILLEELGLIFRKN----- 175
            |::.:.|..|.:|:::|:.::||||:.:||.||...|..|.|:..|.:|::|:...|.:.
Mouse   110 VSTSQNRQTFITSVIKFLRQYGFDGLDLDWEYPGSRGSPPQDKHLFTVLVKEMREAFEQEAIESN 174

  Fly   176 --QLILMVAVLGRRDNRILESYNIPEIVNHSDFIHLMMHDEQDPYHLRLAYNAPLVGYEGSV--- 235
              :|::..||.|...| |...|.|||:..:.||||:|.:|....:......|:||..|....
Mouse   175 RPRLMVTAAVAGGISN-IQAGYEIPELSKYLDFIHVMTYDLHGSWEGYTGENSPLYKYPTETGSN 238

  Fly   236 ----TDSIM-HWKRNGGAPEKLILGIPLFVRSFTMDRNQST--VGSACKGPGRQTKQSHRPGFMT 293
                .|.:| :||.||...||||:|.|.:..:|.: ||.|.  :|:...|.|.....:.:.||..
Mouse   239 AYLNVDYVMNYWKNNGAPAEKLIVGFPEYGHTFIL-RNPSDNGIGAPTSGDGPAGPYTRQAGFWA 302

  Fly   294 YNEWCV-QQSKWSRMFDQLAKVPYATRGDQWVSYENPRSIWAKMHLLQEHKLGGAMAWTIDVDDF 357
            |.|.|. .:|..:.::|...:||||.:.::|:.|:|.:|...|...|:::..||||.|.||:|||
Mouse   303 YYEICTFLRSGATEVWDASQEVPYAYKANEWLGYDNIKSFSVKAQWLKQNNFGGAMIWAIDLDDF 367

  Fly   358 RGRCGEQHGLLRVIFSALGDKNGLTTE---------KPTTE----------------ASGLCPH- 396
            .|...:|...  .:.|.|....|::||         :|.|.                .||.|..
Mouse   368 TGSFCDQGKF--PLTSTLNKALGISTEGCTAPDVPSEPVTTPPGSGSGGGSSGGSSGGSGFCADK 430

  Fly   397 -DGFSRDGWDCRLYHECRDGERIYYECLEGQYFDENQIVC 435
             ||......|...:.:|.:|......|..|..||.:...|
Mouse   431 ADGLYPVADDRNAFWQCINGITYQQHCQAGLVFDTSCNCC 470

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.