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Protein Alignment Cht12 and Chit1

DIOPT Version :9

Sequence 1:	NP_726022.1	Gene:	Cht12 / 246535	FlyBaseID:	FBgn0050293	Length:	470	Species:	Drosophila melanogaster
Sequence 2:	NP_001271454.1	Gene:	Chit1 / 71884	MGIID:	1919134	Length:	464	Species:	Mus musculus

Alignment Length:	490	Identity:	139/490 - (28%)
Similarity:	217/490 - (44%)	Gaps:	95/490 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 MIMIFLICGCIAKEYNVFCQYDLGSYYYKGRSQFFEWHLDSRLCTHLVLGSGIGVDGDS-GELRI 72
            |.::.:..|..||   :.|.....|.|.....:||...:|..||||::.... |:|... ..:..
Mouse    11 MTLLMVQWGSAAK---LVCYLTNWSQYRTEAVRFFPRDVDPNLCTHVIFAFA-GMDNHQLSTVEH 71

  Fly    73 TDKILLLEKDKLSSVKTMKWDSIKKVMFTIGGWEEDSSSFSRMVASPKKRDNFYSSMLEFMFRWG 137
            .|::|..|   |:|:||.  :...|.:..:|||...:..|:.|||:...|..|..|.|.|:...|
Mouse    72 NDELLYQE---LNSLKTK--NPKLKTLLAVGGWTFGTQKFTDMVATASNRQTFVKSALSFLRTQG 131

  Fly   138 FDGVQIDWRYPTLLGGHPDDRQNFVILLEELGLIFR-------KNQLILMVAVLGRRDNRILES- 194
            |||:.:||.:|...|....|::.|..|:::|...|:       |.:|:|..||  ..|..::::
Mouse   132 FDGLDLDWEFPGGRGSPTVDKERFTALIQDLAKAFQEEAQSSGKERLLLTAAV--PSDRGLVDAG 194

  Fly   195 YNIPEIVNHSDFIHLMMHDEQDPYHLRLAYNAPLVGYEG--------SVTDSIMHWKRNGGAPEK 251
            |.:.:|....|||:||.:|..........:|:||...:|        :|..::..|.:.|....|
Mouse   195 YEVDKIAQSLDFINLMAYDFHSSLEKTTGHNSPLYKRQGESGAAAEQNVDAAVTLWLQKGTPASK 259

  Fly   252 LILGIPLFVRSFTM-DRNQSTVGSACKGPGRQTKQSHRPGFMTYNEWCVQQSKWS---RMFDQLA 312
            ||||:|.:.||||: ..:.:.||:...|||.....:...|.:.|.|.|    .|.   |:.||
Mouse   260 LILGMPTYGRSFTLASSSDNGVGAPATGPGAPGPYTKDKGVLAYYEAC----SWKERHRIEDQ-- 318

  Fly   313 KVPYATRGDQWVSYENPRSIWAKMHLLQEHKLGGAMAWTIDVDDFRGR-CGE-QHGLLRVIFSAL 375
            |||||.:.:||||:::..|..||...|::..|||||.|.:|:|||:|. |.: .:.|:|.:...|
Mouse   319 KVPYAFQDNQWVSFDDVESFKAKAAYLKQKGLGGAMVWVLDLDDFKGSFCNQGPYPLIRTLRQEL 383

  Fly   376 GDKNGLTTEKPTT----------------------------EASGLCPHDGFSRDGWDCRLYHEC 412
                .|.:|.|.:                            :|.|:.|:.|
Mouse   384 ----NLPSETPRSPEQIIPEPRPSSMPEQGPSPGLDNFCQGKADGVYPNPG-------------- 430

  Fly   413 RDGERIYYECLEGQYFDENQIVCRPA----AEVKC 443
              .|..||.|..|:.|.::   |.|.    |..||
Mouse   431 --DESTYYNCGGGRLFQQS---CPPGLVFRASCKC 460

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.