Protein Alignment Cht12 and LOC5667101

DIOPT Version :10

• Sequence 1: NP_726022.1
• Gene: Cht12 / 246535
• FlyBaseID: FBgn0050293
• Length: 470
• Species: Drosophila melanogaster
• Sequence 2: XP_061496499.1
• Gene: LOC5667101 / 5667101
• VectorBaseID: AGAMI1_001978
• Length: 468
• Species: Anopheles gambiae
• Alignment Length: 480
• Identity: 143/480 - (29%)
• Similarity: 226/480 - (47%)
• Gaps: 61/480 - (12%)

  Fly     7 VFMIMIFLICGCIAKEYN-----VFCQYDLGSYYYKGRSQFFEWHLDSRLCTHLVLG-SGIGVDG 65
            ::.|::...|..:|...|     |.|.|...:..|....:|...:::..|||.||.. ..|..||
Mosquito     7 LWFILLVTACSLLAAVENRKYGEVVCYYGSWASGYVASGKFAVENINPALCTQLVYSFYNIKPDG 71

  Fly    66 D---SGELRITDKILLLEKDKLSSVKTMKWDSIKKVMFTIGGWEEDSSSFSRMVASPKKRDNFYS 127
            .   ..|...::..:|    ||:.:|  |.:...|.:..|||:...:.|||::..:|:.|..|..
Mosquito    72 TIVIPNEATFSEATIL----KLNDLK--KTNPALKTLAAIGGYNAGTESFSKVAKTPELRTTFAR 130

  Fly   128 SMLEFMFRWGFDGVQIDWRYPTLLGGHPDDRQNFVILLEELGLIFRKNQLILMVAVLGR--RDNR 190
            :...|:.::.|||:.|||.||...     |:.|||..|:||...|..::.:|.|||.|.  ..|
Mosquito   131 NAAAFLKKYRFDGMDIDWEYPVAA-----DKANFVPFLKELSTAFSPSKYLLTVAVGGTSFEGN- 189

  Fly   191 ILESYNIPEIVNHSDFIHLMMHDEQDPYHLRLAYNAPL---------VGYEGSVTDS--IMHWKR 244
              :.|:||.|....:||:||.:|.|..|.: ..::|||         ..|:.::...  |.:|..
Mosquito   190 --DRYDIPAISKVVNFINLMTYDMQGNYGV-TRHHAPLKQGPAALDNTDYKQALNAEAVIAYWLS 251

  Fly   245 NGGAPEKLILGIPLFVRSFTMDR-NQSTVGSACKG---PGRQTKQSHRPGFMTYNEWCVQQSKWS 305
            .|....||.||||.:.|||.:.: ....||:...|   ||..|:|:   |.:.|.|.|.......
Mosquito   252 KGAPANKLNLGIPFYGRSFKLAKPTVDGVGAPVSGVGTPGPVTRQA---GSLAYYEICNSSMLTR 313

  Fly   306 RMFDQLAKVPYATRGDQWVSYENPRSIWAKMHLLQEHKLGGAMAWTIDVDDFRGRCGEQHGLLRV 370
            :.:|.:....:|:.|.:||||::..||..|..::.::.|||.|.|:||:|||.|:||.:..||..
Mosquito   314 KQYDSVQVGAFASGGGEWVSYDSVESIGQKCDVIAKYGLGGGMVWSIDMDDFTGKCGPKFALLTA 378

  Fly   371 IFSALGDKNGLTTE--------------KPTTEASG--LCPHDGFSRDGWDCRLYHECRDGERIY 419
            :...:..|....|.              ||.:..:|  :|..||:.||..:|.:|:.|.:|.|:.
Mosquito   379 LNGCVNRKAPSATPATPSTPGTPSTPVVKPPSGQTGPFVCTRDGYFRDSQNCTMYYRCYNGGRVE 443

  Fly   420 Y-ECLEGQYFDENQIVCRPAAEVKC 443
            : .|..|.||:|...:|...:.|||
Mosquito   444 HGTCPGGLYFNERLSICDYPSNVKC 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cht12	NP_726022.1	GH18_chitinase-like	25..375	CDD:471972	115/370 (31%)
		ChtBD2	394..438	CDD:214696	16/44 (36%)
LOC5667101	XP_061496499.1	None