DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht12 and ctbs

DIOPT Version :9

Sequence 1:	NP_726022.1	Gene:	Cht12 / 246535	FlyBaseID:	FBgn0050293	Length:	470	Species:	Drosophila melanogaster
Sequence 2:	NP_001011500.1	Gene:	ctbs / 497004	XenbaseID:	XB-GENE-975891	Length:	369	Species:	Xenopus tropicalis

Alignment Length:	402	Identity:	86/402 - (21%)
Similarity:	149/402 - (37%)	Gaps:	120/402 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 VFMIMIFLIC--GCIAKEYNVFCQ-------YDLGSYYYKGRS-QFFEWHLDSRLCTHLVLGSGI 61
            :|:::...:|  ||...:..: |:       :::..:|.||:: :|::|   |::.|..:.|.
Frog    14 LFIMLCVSLCAAGCPCTDPRL-CEPITDSRDFEVLVFYTKGKNWKFYDW---SQVTTIALFGK-- 72

  Fly    62 GVDGDSGELRITDKILLLEKDKLSSVKTMKWDSIKKVMFTIGGWEEDSSSFSRMVASP-----KK 121
                       .|..||.......:...:|.|                      |..|     |.
Frog    73 -----------YDPELLCFAHSKGARLVLKGD----------------------VPLPYIVDLKN 104

  Fly   122 RDNFYSSMLEFMFRWGFDGVQIDWRYPTLLGGHPDDRQNFVILLEELGLIFRK----NQLILMVA 182
            |.::.:..:|.......||:.:|.. .::|.|.| :......|:||....|.:    :|:...||
Frog   105 RTSWITQKVELAKSQFMDGINLDIE-QSVLKGSP-EYYALTALVEETTEAFHREIPGSQVTFDVA 167

  Fly   183 -----VLGRRDNRILESYNIPEIVNHSDFIHLMMHDEQDPYHLR--LAYNAP----LVGYEGSVT 236
                 |    |.|   .||...|....||:.:|.:|||......  .:.|:|    |.||:....
Frog   168 WSPDCV----DER---CYNYTGIAESCDFLFVMSYDEQSQIWTECVASANSPLNKTLSGYQKFTQ 225

  Fly   237 DSIMHWKRNGGAPEKLILGIPLFVRSF---TMDRNQSTV------GSACK-GPGRQ------TKQ 285
            ..|        .|:||::|:|.:...:   .::.|..|:      |:.|. ..|:|      |||
Frog   226 LDI--------DPKKLVMGVPWYGYDYPCLDLEDNNCTLKEVPFRGAPCSDAAGKQIPYSKITKQ 282

  Fly   286 SHRPGFMTYNEWCVQQSKWSRMFDQLAKVPYATRGD-----QWVSYENPRSIWAKMHLLQEHKLG 345
                         |..|...|::|.:.|.|:....|     ..|.|::|.||..|...:::..|.
Frog   283 -------------VNSSLTGRLWDDVQKSPFYNYKDAKGQFHQVWYDDPVSISLKSAYIKKLGLR 334

  Fly   346 GAMAWTIDVDDF 357
            |...|..|:.|:
Frog   335 GIGMWNGDLLDY 346

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht12	NP_726022.1	GH18_chitinase-like	25..375	CDD:299167	82/382 (21%)
		Glyco_hydro_18	47..355	CDD:279094	75/348 (22%)
		ChtBD2	394..438	CDD:214696
ctbs	NP_001011500.1	GH18_chitobiase	9..363	CDD:119354	86/402 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910