Protein Alignment Cht12 and LOC4577133

DIOPT Version :10

• Sequence 1: NP_726022.1
• Gene: Cht12 / 246535
• FlyBaseID: FBgn0050293
• Length: 470
• Species: Drosophila melanogaster
• Sequence 2: XP_001237469.4
• Gene: LOC4577133 / 4577133
• VectorBaseID: AGAMI1_000649
• Length: 577
• Species: Anopheles gambiae
• Alignment Length: 553
• Identity: 132/553 - (23%)
• Similarity: 229/553 - (41%)
• Gaps: 127/553 - (22%)

  Fly     9 MIMIFLICGCIAKEYNVFCQYDLGSYYYKGRSQFFEWHLDSRLCTHLVLGSGIGVDGDSGELRIT 73
            ::.:..:.....::..:.|.:...:.|.....::....:.:.:|||::. |.||||..:.::.:.
Mosquito    18 LLAVLPLLAAQGQKARIVCYFSNWAIYRPDVGRYTIDDIPAEMCTHIIY-SFIGVDDSNYQVLVI 81

  Fly    74 DKILLLEKDKLSSVKTMKWD-SIKKVMFTIGGWEEDSSSFSRMVASPKKRDNFYSSMLEFMFRWG 137
            |..:.||:....:...::.. ...|....:|||.|....:|:|||..::|.:|.||:::||..:|
Mosquito    82 DPEVDLEQSGFRNFTELRQRYPHAKYQIAVGGWAEGGKKYSQMVAVKERRQSFISSVVQFMKVYG 146

  Fly   138 FDGVQIDWRYPTLL--GGHPDDRQNFVILLEELGLIFRKN----QLILMVAVLGRRDNRILESYN 196
            |||..:||.||...  ||...|:..|...:|||...|.:.    ::.:.|.|   .:.|:.|.|:
Mosquito   147 FDGFDLDWEYPGAADRGGSFGDKDKFFYFVEELRRAFDREGRGWEITMAVPV---ANFRLQEGYH 208

  Fly   197 IPEIVNHSDFIHLMMHDEQDPYHLRLAYNAPLV-------GYEG-SVTDSIMHWKRNGGAPEKLI 253
            :||:..:.|.||.|.:|.:..:......::||.       .||. :|.|.:..|...|..|.||:
Mosquito   209 VPELCENLDAIHCMTYDLRGNWAGFADVHSPLYKRPHDQWAYEKLNVNDGVQLWVNYGCPPNKLV 273

  Fly   254 LGIPLFVRSFTMDRNQST--VGSACK---GPGRQTKQSHRPGFMTYNEWCV----QQSKWSRMFD 309
            :|:|.:.|:||:..:.:.  :||...   |.|.....::..||:.|.|.|.    ::..|::.:|
Mosquito   274 IGVPFYGRTFTLSASTTNPKLGSYINKEAGGGDPGPYTNATGFLAYYEICTEVQDEEKGWTKKWD 338

  Fly   310 QLAKVPYATRGDQWVSYENPRSIWAKMHLLQEHKLGGAMAWTIDVDDFRGRCGEQHGLLRVIFSA 374
            ::...||..:|.|:|.||:.||:..||..:::....|||.|.||:|||.|.||.::.|::|::..
Mosquito   339 EVGLCPYTYKGTQFVGYEDERSLQHKMDWIKQKGYAGAMTWAIDMDDFHGLCGPENALMKVLYDG 403

  Fly   375 LGD----------------------------------------------------------KNGL 381
            :.|                                                          :...
Mosquito   404 MKDYVVPEPTVTTTPRPEWNRPPSTMSSDGEQTTTRPATTTTTYKPRPTTTVAPTTRTTTARRTT 468

  Fly   382 TTEKPTTEASGLCPHDGFSRD-----------------------GW-------DCRLYHECRDGE 416
            ||.||||    :.|.|..|.:                       |:       ||..|:.|..|:
Mosquito   469 TTRKPTT----ILPPDTDSEEDREEPAMPPAAPEREDESEIDCSGYKDFVPSVDCTKYYRCVHGQ 529

  Fly   417 RIYYECLEGQYFDENQIVC-------RPAAEVK 442
            .:.:.|..|..|.....||       ||....|
Mosquito   530 PVEFVCKPGTVFHTALNVCDWPENADRPECRTK 562

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cht12	NP_726022.1	GH18_chitinase-like	25..375	CDD:471972	108/373 (29%)
		ChtBD2	394..438	CDD:214696	15/80 (19%)
LOC4577133	XP_001237469.4	None