DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht12 and chit1

DIOPT Version :9

Sequence 1:	NP_726022.1	Gene:	Cht12 / 246535	FlyBaseID:	FBgn0050293	Length:	470	Species:	Drosophila melanogaster
Sequence 2:	NP_001005792.1	Gene:	chit1 / 448265	XenbaseID:	XB-GENE-5801457	Length:	492	Species:	Xenopus tropicalis

Alignment Length:	479	Identity:	127/479 - (26%)
Similarity:	203/479 - (42%)	Gaps:	91/479 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 YNVFCQYDLGSYYYKGRSQFFEWHLDSRLCTHLVLGSGIGVDGDSGELRITDKILLLEKDKLSSV 87
            |.:.|.:...|.|....:::...::|.:|||||:.................|.:|.
Frog    22 YKLVCYFTNWSQYRPEPAKYMPGNIDPKLCTHLIYAFATMNSNKIAPYEWNDDVLY--------- 77

  Fly    88 KTMKWDSIKK------VMFTIGGWEEDSSSFSRMVASPKKRDNFYSSMLEFMFRWGFDGVQIDWR 146
              .:::::|:      .:..||||...:..|:.||:|...|..|..|::|::..:||:|:.:|:.
Frog    78 --KQYNALKQQNPNLVTLLAIGGWNFGTQKFTEMVSSAGNRKIFIDSVIEYLRLYGFNGIDLDFE 140

  Fly   147 YPTLLGGHPDDRQNFVILLEELGLIFR-----KNQ-LILMVAVLGRRDNRILESYNIPEIVNHSD 205
            ||...|..|:|:..|.||.:|:...|.     .|| .:||.|.:......|...|.|.||....|
Frog   141 YPGSRGSPPEDKHRFTILTQEMLKAFEDEAAATNQSRLLMTAAVSAGKGTIDAGYEIAEIGKTLD 205

  Fly   206 FIHLMMHDEQDPYHLRLAYNAPLVGYEGS----------VTDSIMHWKRNGGAPEKLILGIPLFV 260
            ||.:|.:|....:.....:|:||.  :||          :..::.:||.||...:||::|.|.:.
Frog   206 FISVMTYDFHGGWDPVSGHNSPLC--KGSKDTGDFQYFNIRYAMNYWKDNGVPAQKLLIGFPTYG 268

  Fly   261 RSFTMDRNQS----TVGSACKGPGRQTKQSHRPGFMTYNEWCVQQS----KWSRMFDQLAKVPYA 317
            |:|   ||.:    .||....|.|...:.:...||..|.|.|...|    .|  :.||  |||||
Frog   269 RTF---RNPNPSNCDVGIPVSGAGSAGQYTREAGFWAYYEICTWLSGTTINW--IADQ--KVPYA 326

  Fly   318 TRGDQWVSYENPRSIWAKMHLLQEHKLGGAMAWTIDVDDFRGR-CGE-QHGLLRVIFSAL----- 375
            .:|::||.::|..|...|:..|:|....|||.|.||:|||.|. |.: ::.|:..:.|.|
Frog   327 CKGNEWVGFDNQDSYECKVKFLKESGFAGAMVWAIDLDDFSGTFCNQGKYPLISHLKSLLEGSVT 391

  Fly   376 --------------------GDKN--------GLTTEKPTTEASGLCPH------DGFSRDGWDC 406
                                |:..        |.||...||....:.|:      ||...:..:.
Frog   392 KCPGNPCDIVPTEPPSPTTSGETTTSQAKPTPGETTTSTTTSGDEVDPNFCAGKSDGLYENRINF 456

  Fly   407 RLYHECRDGERIYYECLEGQYFDE 430
            ..::.|..|.....:|.:|..|||
Frog   457 NRFYICAGGSTYPMKCADGLVFDE 480

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht12	NP_726022.1	GH18_chitinase-like	25..375	CDD:299167	109/381 (29%)
		Glyco_hydro_18	47..355	CDD:279094	99/337 (29%)
		ChtBD2	394..438	CDD:214696	10/43 (23%)
chit1	NP_001005792.1	GH18_chitolectin_chitotriosidase	24..386	CDD:119351	109/381 (29%)
chit1	NP_001005792.1	CBM_14	442..491	CDD:366726	9/39 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1289629at2759
OrthoFinder	1	1.000	-	-		FOG0000107
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X91
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920