DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht12 and Cht9

DIOPT Version :9

Sequence 1:	NP_726022.1	Gene:	Cht12 / 246535	FlyBaseID:	FBgn0050293	Length:	470	Species:	Drosophila melanogaster
Sequence 2:	NP_611543.3	Gene:	Cht9 / 37392	FlyBaseID:	FBgn0034582	Length:	368	Species:	Drosophila melanogaster

Alignment Length:	365	Identity:	126/365 - (34%)
Similarity:	193/365 - (52%)	Gaps:	11/365 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 MIMIFLICGCIAKEYNVFCQYDLGSYYYKGRSQFFEWHLDSRLCTHLVLGSGIGVDGDSGELRIT 73
            ::.:..:...|..|..|.|.:...:.|..|..:|...::|:.|||||.. |..|:: |:||::..
  Fly     7 LLAVLCLSQVIGAERIVNCYWGTWANYRSGNGKFDVSNIDAGLCTHLSY-SFFGIN-DNGEIQSL 69

  Fly    74 DKILLLEKDKLSSVKTMK-WDSIKKVMFTIGGWEEDSSSFSRMVASPKKRDNFYSSMLEFMFRWG 137
            |..|..:...::...::| .:|..||:..:|||.|.|:.:|.|.....||.||.:|.|..:...|
  Fly    70 DTWLDYDLGFINQAISLKNQNSNLKVLAVVGGWNEGSTKYSSMSGDWYKRQNFINSALNLLRNHG 134

  Fly   138 FDGVQIDWRYPTLLGGHPDDRQNFVILLEELGLIFRKNQLILMVAVLGRRDNRILESYNIPEIVN 202
            |||:.:||.||...||:.:||.|||.||.|:...|......|.:|| |..::....||.|..|..
  Fly   135 FDGLDLDWEYPNQRGGNWNDRANFVTLLREIKEAFAPYGYELGIAV-GAGESLASASYEIANIAQ 198

  Fly   203 HSDFIHLMMHDEQDPYHLRLAYNAPLVGYEGSVTDSIMHWKRNGGAPEKLILGIPLFVRSFTM-D 266
            ..|||::|.:|.......:..:|||    :.:|.::|..|...|....||:||:..:.|||.: |
  Fly   199 QVDFINVMTYDFAMASDGQTGFNAP----QWAVENAINFWLSQGAPANKLVLGVGTYGRSFQLSD 259

  Fly   267 RNQSTVGSACKGPGRQTKQSHRPGFMTYNEWCVQQSKWSRMFDQLAKVPYATRGDQWVSYENPRS 331
            .:|:..|:.|:|.|.....:...|::.|||.|  |:.|..:||.....|||..||||||::|..|
  Fly   260 SSQNWPGAPCRGEGSAGSYTGSTGYLGYNEIC--QNNWHTVFDYDNAAPYAYSGDQWVSFDNVLS 322

  Fly   332 IWAKMHLLQEHKLGGAMAWTIDVDDFRGRCGEQHGLLRVI 371
            :..||.......|.|||.|:::.||:||:|||.:.||:.|
  Fly   323 VQYKMDFALSKGLAGAMIWSLETDDYRGQCGETYPLLKTI 362

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht12	NP_726022.1	GH18_chitinase-like	25..375	CDD:299167	124/349 (36%)
		Glyco_hydro_18	47..355	CDD:279094	109/309 (35%)
		ChtBD2	394..438	CDD:214696
Cht9	NP_611543.3	GH18_chitolectin_chitotriosidase	23..366	CDD:119351	124/349 (36%)
Cht9	NP_611543.3	Glyco_18	23..346	CDD:214753	114/331 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469220
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	160	1.000	Inparanoid score	I1632
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264489at33208
OrthoFinder	1	1.000	-	-		FOG0000107
OrthoInspector	1	1.000	-	-		otm46727
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X91
	9	8.900