DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht12 and Idgf1

DIOPT Version :9

Sequence 1:	NP_726022.1	Gene:	Cht12 / 246535	FlyBaseID:	FBgn0050293	Length:	470	Species:	Drosophila melanogaster
Sequence 2:	NP_477258.1	Gene:	Idgf1 / 34978	FlyBaseID:	FBgn0020416	Length:	439	Species:	Drosophila melanogaster

Alignment Length:	454	Identity:	109/454 - (24%)
Similarity:	197/454 - (43%)	Gaps:	98/454 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 FQYVFMIMIFLICGCIAKEYNVFCQYDLGSYYYKGRSQFFEWHLDSRL--CTHLVLG-SGIGVDG 65
            ||..:::.:..:........|:.|.||..||..:|.::.....||..|  |||||.| :|:
  Fly     3 FQLFYILGLLSVTSLTHAASNLICYYDSNSYLRQGLAKMHTNELDLALQFCTHLVYGYAGL---- 63

  Fly    66 DSGELRI----TDKILLLEKDKLSSVKTMKWDSIKKVMFTIGGWEE-DSSSFSRMV----ASPKK 121
            .||.|.:    .|..:...|| ::::: .|:..: |::.::||..: |.:..::.|    |:...
  Fly    64 KSGTLELFSLNVDLDMFYYKD-ITALR-QKFPQL-KILLSVGGDRDVDEAHPNKYVELLEANRTA 125

  Fly   122 RDNFYSSMLEFMFRWGFDGVQIDWRYPT--------LLGGH------------------PDDRQN 160
            :.||..|.:..:.|.||||:.:.::.|.        .||.:                  .:.:..
  Fly   126 QQNFIDSSMILLKRNGFDGLDLAFQLPRNKPRKVHGSLGSYWKSFKKLFTGDFVVDPQAEEHKSQ 190

  Fly   161 FVILLEELGLIFRKNQLILMVAVLGRRDNRILESYNIPEIVNHSDFIHLMMHDEQDPYHLR---- 221
            |..|:..:...||...|:|.:.||...::...  :::|::....|:|:|...|...|  ||
  Fly   191 FTDLVGNIKNAFRSANLMLSLTVLPNVNSTWY--FDVPKLHPQFDYINLAAFDFLTP--LRNPEE 251

  Fly   222 LAYNAPLVGYEG-------SVTDSIMHWKRNGGAPEKLILGIPLFVRSFTMDRNQSTVGS----- 274
            ..:.||:...:.       :|...|.:|.:|....:||.|||..:.|::.:.:.....|:
  Fly   252 ADFTAPIFFQDEQNRLPHLNVEFQINYWLQNHCPGQKLNLGIASYGRAWKLSKGSGLSGAPIVHE 316

  Fly   275 AC-KGPGRQTKQSHRPGFMTYNEWC--VQQSKWSRMFDQLA---KVP--------YATR-----G 320
            .| ..||....|| ..|.:::.|.|  :.|:..::...:||   ||.        ||.|     |
  Fly   317 TCGVAPGGIQIQS-AEGLLSWPEICSKLSQNASAQYRGELAPLRKVTDLTQKYGNYALRPADDNG 380

  Fly   321 D--QWVSYENP-----RSIWAKMHLLQEHKLGGAMAWTIDVDDFRGRC-GEQHGLLRVIFSALG 376
            |  .|:|:::|     ::::||     ...|||...:.:..|||||.| |:::.:||.|...:|
  Fly   381 DFGVWLSFDDPDFAGIKAVYAK-----GKGLGGIALFDLSYDDFRGLCTGQKYPILRSIKYFMG 439

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht12	NP_726022.1	GH18_chitinase-like	25..375	CDD:299167	105/430 (24%)
		Glyco_hydro_18	47..355	CDD:279094	89/387 (23%)
		ChtBD2	394..438	CDD:214696
Idgf1	NP_477258.1	GH18_IDGF	23..438	CDD:119352	106/431 (25%)
Idgf1	NP_477258.1	Glyco_18	24..417	CDD:214753	95/409 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463819
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840