DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht12 and CG8460

DIOPT Version :9

Sequence 1:	NP_726022.1	Gene:	Cht12 / 246535	FlyBaseID:	FBgn0050293	Length:	470	Species:	Drosophila melanogaster
Sequence 2:	NP_609190.2	Gene:	CG8460 / 34115	FlyBaseID:	FBgn0031996	Length:	402	Species:	Drosophila melanogaster

Alignment Length:	230	Identity:	53/230 - (23%)
Similarity:	91/230 - (39%)	Gaps:	46/230 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   137 GFDGVQID-WRYPTLLGGHPDDRQNFVILLEELGLIFRKNQ--LILMVAVLGRRDNRILESYNIP 198
            ||||:.:: |   :.|.|..||:..:.::| ::....:|.|  |||::....:....:....::.
  Fly   194 GFDGLVLEVW---SQLAGRIDDKILYTLVL-QMAKELQKQQLRLILVIPPFRKETGHLFGEKHMD 254

  Fly   199 EIVNHSDFIHLMMHDEQDPYHLRLAYNAPLVGYEGSVTDSIMHWKRNGGAPE----------KLI 253
            ::..|.....||.:|.....  |...||||. :.....::|        |||          |::
  Fly   255 KLFKHIYAFSLMTYDFSSVQ--RPGANAPLY-FVRKAVETI--------APEGCADMTAKRAKIL 308

  Fly   254 LGIPLFVRSFTMDRNQSTVGSACKGPGRQTKQSHRPGFMTYNEWCVQQSKWSRMFDQLAKVPYAT 318
            ||:.::...:|.|.......|......|..|:     .:||:|..|:.      |.::..    .
  Fly   309 LGLNMYGNDYTPDGGGPITFSQYLDLVRHVKK-----HLTYDERDVEN------FFEIKN----D 358

  Fly   319 RGDQWVSYENPRSIWAKMHLLQEHKLG-GAMAWTI 352
            .|...|.|....||..::.|.||  || |...|.:
  Fly   359 DGRHIVFYPTLYSINERIKLAQE--LGTGISIWEL 391

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht12	NP_726022.1	GH18_chitinase-like	25..375	CDD:299167	53/230 (23%)
		Glyco_hydro_18	47..355	CDD:279094	53/230 (23%)
		ChtBD2	394..438	CDD:214696
CG8460	NP_609190.2	GH18_SI-CLP	81..402	CDD:119355	53/230 (23%)
CG8460	NP_609190.2	Glyco_18	86..393	CDD:214753	53/230 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463833
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930