Protein Alignment Cht12 and Chit1

DIOPT Version :10

• Sequence 1: NP_726022.1
• Gene: Cht12 / 246535
• FlyBaseID: FBgn0050293
• Length: 470
• Species: Drosophila melanogaster
• Sequence 2: NP_001073157.1
• Gene: Chit1 / 289032
• RGDID: 1305646
• Length: 464
• Species: Rattus norvegicus
• Alignment Length: 466
• Identity: 135/466 - (28%)
• Similarity: 218/466 - (46%)
• Gaps: 58/466 - (12%)

  Fly    11 MIFLICGCIAKEYNVFCQYDLGSYYYKGRSQFFEWHLDSRLCTHLVLG-SGIGVDGDSGELRITD 74
            ::.:..|..||   :||.:...:.|..|.::|....:|..||||::.. :|:. :.....:...|
  Rat    13 LLMIQWGSAAK---LFCYFTNWAQYRSGAARFLPRDVDPNLCTHVIYAFAGLN-NHQVSTVEPND 73

  Fly    75 KILLLEKDKLSSVKTMKWDSIKKVMFTIGGWEEDSSSFSRMVASPKKRDNFYSSMLEFMFRWGFD 139
            ::...|   |:|:|  |.:...|.:..:|||...:..|:.|||:...|..|.:|.|.|:...|||
  Rat    74 ELFYQE---LNSLK--KRNPKLKTLLAVGGWSFGTQKFTDMVATASTRQTFVNSALSFLRTHGFD 133

  Fly   140 GVQIDWRYPTLLGGHPDDRQNFVILLEELGLIFR-------KNQLILMVAV-LGRRDNRILESYN 196
            |:.:||.||...|....|::.|..|:::|...|:       |::|:|..|| .||  ..:...|.
  Rat   134 GLDLDWEYPGSRGSPAVDKERFTALIQDLAKAFQEEARASGKSRLLLTAAVPTGR--GHVDAGYE 196

  Fly   197 IPEIVNHSDFIHLMMHDEQDPYHLRLAYNAPLVGYEG--------SVTDSIMHWKRNGGAPEKLI 253
            :.:||...|||:||.:|....:.....:|:||...:|        :|..::..|.:.|....||:
  Rat   197 VDKIVQSLDFINLMAYDFHSSWDKTTGHNSPLYKRQGETGKDAEKNVDAAVTLWLQKGTPASKLM 261

  Fly   254 LGIPLFVRSFTM-DRNQSTVGSACKGPGRQTKQSHRPGFMTYNEWCVQQSKWSRMFDQLAKVPYA 317
            ||:|.:.||||: ..:.|.||:...|||.....:...|.:.|.|.|..:.| .|:.||  ||||.
  Rat   262 LGMPAYGRSFTLASSSDSGVGAPATGPGAPGPYTKEKGILVYFEVCSWKGK-QRIEDQ--KVPYV 323

  Fly   318 TRGDQWVSYENPRSIWAKMHLLQEHKLGGAMAWTIDVDDFRGR-CGE-QHGLLRVIFSALGDKNG 380
            ::|:|||.:::..|..||...:::..|||||.|.:|.|||:|. |.| |:.|:|.:...|...:|
  Rat   324 SQGNQWVGFDDRESFRAKAAYVKQKGLGGAMVWILDGDDFKGSFCNEGQYPLIRTLHQELSLSSG 388

  Fly   381 LTTEKPTTEASGLCPH---------------------DGFSRDGWDCRLYHECRDGERIYYECLE 424
             ....|..|..|  ||                     ||...:..:...::.|..|....:.|..
  Rat   389 -PPRSPEQEVPG--PHQPSEPEQGPSPGLDDFCQGKADGLYPNPTEKSSFYSCGGGRLFQHSCPP 450

  Fly   425 GQYFDENQIVC 435
            |..|.::...|
  Rat   451 GLVFIDSCKCC 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cht12	NP_726022.1	GH18_chitinase-like	25..375	CDD:471972	117/369 (32%)
		ChtBD2	394..438	CDD:214696	10/63 (16%)
Chit1	NP_001073157.1	GH18_chitolectin_chitotriosidase	24..383	CDD:119351	117/369 (32%)
		ChtBD2	416..463	CDD:214696	8/46 (17%)