DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht12 and chil-16

DIOPT Version :9

Sequence 1:	NP_726022.1	Gene:	Cht12 / 246535	FlyBaseID:	FBgn0050293	Length:	470	Species:	Drosophila melanogaster
Sequence 2:	NP_496020.1	Gene:	chil-16 / 187732	WormBaseID:	WBGene00011158	Length:	440	Species:	Caenorhabditis elegans

Alignment Length:	382	Identity:	90/382 - (23%)
Similarity:	169/382 - (44%)	Gaps:	67/382 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 LGSYYYKGRSQFFEWHLDSRLCTHLVLG-SGIGVDG----DSGELRITDKILLLEKDKLSSVKTM 90
            :|.||..|........| ::| ||.|.. ..:..||    :|.:.:  :..|.|.  ||:|:  :
Worm    89 VGYYYRNGNDSIMMGQL-AKL-THAVFAFLELHPDGTIHFESRKAK--ESFLYLR--KLASI--L 145

  Fly    91 KWDSIKKVMFTIGGWEEDSSSFSRMVASPKKRDNFYSSMLEFMFRWGFDGVQIDWRYPTLLGGHP 155
            |:|:  |:||:||| ..::..||.::.:.:.:..|..|::.|:.::..|||.:.|::.:     .
Worm   146 KFDA--KIMFSIGG-PANTQFFSPIIQNEEMKRKFIDSIIYFLKQYKLDGVDLFWKWSS-----S 202

  Fly   156 DDRQNFVILLEELG---LIFRKNQLILMVAVLGRRDNRILESYNIPEIVNHSDFIHLMMHDEQDP 217
            .|:..:...|:||.   ...|:|.:|.:|......|...| .|::.||:.|.||:::...|...|
Worm   203 GDKFTYSSFLQELKHKLRSHRQNYIISIVLPPAGVDTWEL-GYDLEEIMEHVDFMNVYSMDYSGP 266

  Fly   218 YHLR----------LAYN-APLVGYEGSVTDSIMHWKRNGGAPEKLILGIPLFVRSF-----TMD 266
            :..:          ||:| .|...:  :|..::.::......|.|..:.||.:.|.:     .:|
Worm   267 WDNQWGTPTGPSAPLAFNIGPRKNF--NVDWTMKYYSCKTQQPGKFNMVIPFYARYWNNVQEAVD 329

  Fly   267 RNQSTVGSACKGPGRQTKQSHRPG--FMTYNEWCVQQSKWSRMFDQLAKVPYATRGDQ--WVSYE 327
            .......:|      :.:.:...|  :|..:....:.:.|    |.|...||..:.|:  :.::|
Worm   330 PRTEVFRNA------EIRNNRADGVPYMDRSSADYKMASW----DNLTSTPYIWKPDERRFFTFE 384

  Fly   328 NPRSIWAKMHLLQEHKLGGAMAWTIDVDDFRGRCGEQHGLLRVIFSALGDKNGLTTE 384
            |.:||..|.....:..|||...|::|:.|        ||  .|:.||:..:..||::
Worm   385 NQKSIAIKTRYAIDMNLGGVWIWSVDMGD--------HG--NVLLSAVASQEFLTSK 431

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht12	NP_726022.1	GH18_chitinase-like	25..375	CDD:299167	87/371 (23%)
		Glyco_hydro_18	47..355	CDD:279094	78/335 (23%)
		ChtBD2	394..438	CDD:214696
chil-16	NP_496020.1	Glyco_18	87..411	CDD:214753	81/350 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160164365
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S3021
OMA	1	1.010	-	-		QHG28694
OrthoDB	1	1.010	-	-		D1289629at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X91
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.710