Protein Alignment Cht12 and CTBS

DIOPT Version :10

• Sequence 1: NP_726022.1
• Gene: Cht12 / 246535
• FlyBaseID: FBgn0050293
• Length: 470
• Species: Drosophila melanogaster
• Sequence 2: NP_004379.1
• Gene: CTBS / 1486
• HGNCID: 2496
• Length: 385
• Species: Homo sapiens
• Alignment Length: 315
• Identity: 69/315 - (21%)
• Similarity: 118/315 - (37%)
• Gaps: 65/315 - (20%)

  Fly    88 KTMKWDSIKKVMFTIGGWEEDSSSFS---------------RMVASPKKRDNFYSSMLEFMFRWG 137
            |:..|..|..|. |.|.::.:...::               :.:..|..|.::.:..|.......
Human    71 KSYDWSQITTVA-TFGKYDSELMCYAHSKGARVVLKGDVSLKDIIDPAFRASWIAQKLNLAKTQY 134

  Fly   138 FDGVQIDW---------RYPTLLGGHPDDRQNFVILLEELGLIFRK----NQLILMVAVLGRRDN 189
            .||:.||.         .|..|           ..|::|....|.:    :|:...||...:..:
Human   135 MDGINIDIEQEVNCLSPEYDAL-----------TALVKETTDSFHREIEGSQVTFDVAWSPKNID 188

  Fly   190 RILESYNIPEIVNHSDFIHLMMHDEQDPY------HLRLAYNAPLVGYEGSVTDSIMHWKRNGGA 248
            |  ..||...|.:..||:.:|.:|||...      .....||..|.||...:..||        .
Human   189 R--RCYNYTGIADACDFLFVMSYDEQSQIWSECIAAANAPYNQTLTGYNDYIKMSI--------N 243

  Fly   249 PEKLILGIPLFVRSFT-MDRNQSTVGSACKGPGRQTKQSHRPGFMTYNEWCVQQSKWS---RMFD 309
            |:||::|:|.:...:| ::.::..|.:..|.|.|....|...|.....:..::|...|   .::|
Human   244 PKKLVMGVPWYGYDYTCLNLSEDHVCTIAKVPFRGAPCSDAAGRQVPYKTIMKQINSSISGNLWD 308

  Fly   310 QLAKVPYATRGD-----QWVSYENPRSIWAKMHLLQEHKLGGAMAWTIDVDDFRG 359
            :..:.||....|     ..|.|:||:||..|...:|.::|.|...|..:..|:.|
Human   309 KDQRAPYYNYKDPAGHFHQVWYDNPQSISLKATYIQNYRLRGIGMWNANCLDYSG 363

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cht12	NP_726022.1	GH18_chitinase-like	25..375	CDD:471972	69/315 (22%)
		ChtBD2	394..438	CDD:214696
CTBS	NP_004379.1	GH18_chitobiase	39..378	CDD:119354	69/315 (22%)