back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cht12 and Ovgp1

DIOPT Version :9

Sequence 1:	NP_726022.1	Gene:	Cht12 / 246535	FlyBaseID:	FBgn0050293	Length:	470	Species:	Drosophila melanogaster
Sequence 2:	NP_031722.1	Gene:	Ovgp1 / 12659	MGIID:	106661	Length:	721	Species:	Mus musculus

Alignment Length:	448	Identity:	124/448 - (27%)
Similarity:	207/448 - (46%)	Gaps:	83/448 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 IFLICGCI-------AKEYNVFCQYDLGSYYYKGRSQFFEWHLDSRLCTHLVLGSGIGVDGDSGE 69
            :.|:.|.:       ...|.:.|.:...::...|.:......||..|||||:.......:.....
Mouse     4 LLLLAGLVLLMKHSDGTAYKLVCYFTNWAHSRPGPASIMPHDLDPFLCTHLIFAFASMSNNQIVA 68

  Fly    70 LRITDK-ILLLEKDKLSSVKTMKWDSIKKVMFTIGGWEEDSSSFSRMVASPKKRDNFYSSMLEFM 133
            ..:.|: :|..|.:||.     :.:...|.:.:||||...:|.|:.|:::...|:.|..|::.|:
Mouse    69 KNLQDENVLYPEFNKLK-----ERNRELKTLLSIGGWNFGTSRFTAMLSTLANREKFIDSVISFL 128

  Fly   134 FRWGFDGVQIDWRYPTLLGGHPDDRQNFVILLEELGLIFRKN-------QLILMVAVLGRRDNRI 191
            ...||||:.:.:.||.|.|..|.||.||:.|:|||...|.:.       :|:|..||.|
Mouse   129 RIHGFDGLDLFFLYPGLRGSPPHDRWNFLFLIEELQFAFEREALLTQHPRLLLSAAVSG------ 187

  Fly   192 LESYNIPEIVNHS----------DFIHLMMHDEQDPYHLRLAYNAPLVGY-EGSVTD--SIMHWK 243
                 ||.|::.|          |||:::.:|....:.....:|:||... |.|.:.  ::.:|:
Mouse   188 -----IPSIIHTSYDALLLGRRLDFINVLSYDLHGSWEKFTGHNSPLFSLPEDSKSSAYAMNYWR 247

  Fly   244 RNGGAPEKLILGIPLFVRSF-TMDRNQSTVGSACKG---PGRQTKQSHRPGFMTYNEWC--VQQS 302
            :.|...:|||:|.|.:.|:| .:..:::.:.:|..|   ||:.|||:   ||:.|.|.|  ||::
Mouse   248 KLGTPADKLIMGFPTYGRNFYLLKESKNGLQTASMGPASPGKYTKQA---GFLAYYEVCSFVQRA 309

  Fly   303 KWSRMFDQLAKVPYATRGDQWVSYENPRSI-WAKMHLLQEHKLGGAMAWTIDVDDFRGR-CGE-- 363
            |  :.:.....||||.:|.:|:.|::..|. :..|::.:|| .||||.||:|:||.||. ||.
Mouse   310 K--KHWIDYQYVPYAFKGKEWLGYDDTISFSYKAMYVKREH-FGGAMVWTLDMDDVRGTFCGNGP 371

  Fly   364 ---QHGLLRVIF--------------------SALGDKNGLTTEKPTTEASGLCPHDG 398
               .|.|..::.                    |..|.:|...||..||:...:.|..|
Mouse   372 FPLVHILNELLVQTESNSTPLPQFWFTSSVNASGPGSENTALTEVLTTDTIKILPPGG 429

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.