Protein Alignment Cht12 and Chia

DIOPT Version :10

• Sequence 1: NP_726022.1
• Gene: Cht12 / 246535
• FlyBaseID: FBgn0050293
• Length: 470
• Species: Drosophila melanogaster
• Sequence 2: NP_997469.1
• Gene: Chia / 113901
• RGDID: 1303058
• Length: 473
• Species: Rattus norvegicus
• Alignment Length: 493
• Identity: 130/493 - (26%)
• Similarity: 214/493 - (43%)
• Gaps: 89/493 - (18%)

  Fly     9 MIMIFLICGCI-------AKEYNVFCQYDLGSYYYKGRSQFFEWHLDSRLCTHLVLG-SGIGVDG 65
            |..:.|:.|.:       ...||:.|.:...:.|..|...|....::..|||||:.. :|:
  Rat     1 MAKLILVTGLVLLLNVQLGSAYNLVCYFTNWAQYRPGLGSFKPDDINPCLCTHLIYAFAGM---- 61

  Fly    66 DSGELRITDKILLLEKDKLSSVKTMKWDSIK---------------KVMFTIGGWEEDSSSFSRM 115
                             :.:.:.|::|:.:.               |.:..||||...::.|:.|
  Rat    62 -----------------QNNQITTIEWNDVTLYKAFNDLKNRNSKLKTLLAIGGWNFGTAPFTTM 109

  Fly   116 VASPKKRDNFYSSMLEFMFRWGFDGVQIDWRYPTLLGGHPDDRQNFVILLEELGLIFRKNQL--- 177
            |::.:.|..|.:|:::|:.::||||:.:||.||...|..|.|:..|.:|::||...|.:..:
  Rat   110 VSTSQNRQTFITSVIKFLRQYGFDGLDLDWEYPGSRGSPPQDKHLFTVLVKELREAFEQEAIESN 174

  Fly   178 ---ILMVAVLGRRDNRILESYNIPEIVNHSDFIHLMMHDEQDPYHLRLAYNAPLVGYE-----GS 234
               :::.|.:....:.|...|.|||:..:.||||:|.:|....:......|:||  |:     ||
  Rat   175 RPRLMVTAAVAAGISNIQAGYEIPELSQYLDFIHVMTYDLHGSWDGYTGENSPL--YKLPTETGS 237

  Fly   235 ----VTDSIM-HWKRNGGAPEKLILGIPLFVRSFTMDRNQST-VGSACKGPGRQTKQSHRPGFMT 293
                ..|.:| :||.||...||||:|.|.:..::.:.....| :|:...|.|.....:.:.||..
  Rat   238 NAYLNVDYVMNYWKDNGAPAEKLIVGFPEYGHTYILSNPSDTGIGAPTSGNGPAGPYTRQAGFWA 302

  Fly   294 YNEWCV-QQSKWSRMFDQLAKVPYATRGDQWVSYENPRSIWAKMHLLQEHKLGGAMAWTIDVDDF 357
            |.|.|. .::..::.:|...:||||.:|::||.|:|.:|...|...|:::..||||.|.||:|||
  Rat   303 YYEICTFLRNGATQDWDAPQEVPYAYKGNEWVGYDNIKSFSVKAQWLKQNNFGGAMIWAIDLDDF 367

  Fly   358 RGRCGEQ--HGLLRVIFSALGDKNG------LTTEKPTT---------------EASGLC--PHD 397
            .|...:|  ..|...:..||.....      |.:|..||               |.||.|  ..|
  Rat   368 TGSFCDQGKFPLTSTLNKALDIPTAGCTAPDLPSEPVTTPPGSGSGGGSSGGGSEGSGFCAGKAD 432

  Fly   398 GFSRDGWDCRLYHECRDGERIYYECLEGQYFDENQIVC 435
            |......|...:..|.:|......|..|..||.:...|
  Rat   433 GLYPVADDRNAFWHCINGITYQQHCQAGLVFDTSCNCC 470

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cht12	NP_726022.1	GH18_chitinase-like	25..375	CDD:471972	105/385 (27%)
		ChtBD2	394..438	CDD:214696	11/44 (25%)
Chia	NP_997469.1	GH18_chitolectin_chitotriosidase	24..387	CDD:119351	105/385 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	395..421		4/25 (16%)
		ChtBD2	426..473	CDD:214696	11/45 (24%)