Protein Alignment CG30289 and Tmprss2

DIOPT Version :10

• Sequence 1: NP_726081.1
• Gene: CG30289 / 246532
• FlyBaseID: FBgn0050289
• Length: 316
• Species: Drosophila melanogaster
• Sequence 2: NP_056590.2
• Gene: Tmprss2 / 50528
• MGIID: 1354381
• Length: 490
• Species: Mus musculus
• Alignment Length: 284
• Identity: 85/284 - (29%)
• Similarity: 133/284 - (46%)
• Gaps: 50/284 - (17%)

  Fly    18 NNNVMSRLLVE----NCGISKDDPYVPNIFGGAKTNIQENPWMVL--VWSSKPCGGSLIARQFVL 76
            :::..||::|.    .||: :.......|.||...:..:.||.|.  |.....||||:|..::::
Mouse   227 SDSCSSRMVVSLRCIECGV-RSVKRQSRIVGGLNASPGDWPWQVSLHVQGVHVCGGSIITPEWIV 290

  Fly    77 TAAHCVSFEDLYVRLGDYETLDPMPY------CLNNHCIPKFYNI--SVDMKIVHENYNGITLQN 133
            ||||||.           |.|....|      .|....:  ||..  .|:..|.|.||:..|..|
Mouse   291 TAAHCVE-----------EPLSSPRYWTAFAGILRQSLM--FYGSRHQVEKVISHPNYDSKTKNN 342

  Fly   134 DIALLRMSEAVEYSDYVRPICLLVGEQMQSIPM-FTVTGWGET-EYGQFSRILLNATLYNMDISY 196
            ||||:::...:.::|.|:|:||.....|..:.. ..::|||.| |.|:.|.:|..|.:..::.|.
Mouse   343 DIALMKLQTPLAFNDLVKPVCLPNPGMMLDLDQECWISGWGATYEKGKTSDVLNAAMVPLIEPSK 407

  Fly   197 CNIK--FNKQADRSQICAG--SHTSNTCKGDSGGPLSSKFHYGNRLLSFQYGL------VSYGSE 251
            ||.|  :|.....:.||||  ..:.::|:||||||          |::.:.|:      .|:||.
Mouse   408 CNSKYIYNNLITPAMICAGFLQGSVDSCQGDSGGP----------LVTLKNGIWWLIGDTSWGSG 462

  Fly   252 RCAANVAGVYTNVSYHREWIFNKM 275
            ...|...|||.||:...:||:.:|
Mouse   463 CAKALRPGVYGNVTVFTDWIYQQM 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30289	NP_726081.1	Tryp_SPc	42..271	CDD:238113	77/250 (31%)
Tmprss2	NP_056590.2	LDLa	112..147	CDD:238060
		SRCR_2	152..247	CDD:464747	5/20 (25%)
		Tryp_SPc	254..485	CDD:238113	79/253 (31%)