Protein Alignment CG30289 and HPN

DIOPT Version :10

• Sequence 1: NP_726081.1
• Gene: CG30289 / 246532
• FlyBaseID: FBgn0050289
• Length: 316
• Species: Drosophila melanogaster
• Sequence 2: NP_002142.1
• Gene: HPN / 3249
• HGNCID: 5155
• Length: 417
• Species: Homo sapiens
• Alignment Length: 298
• Identity: 91/298 - (30%)
• Similarity: 133/298 - (44%)
• Gaps: 54/298 - (18%)

  Fly     1 MEVINAVIAALVC-----LFIANNNVMSRLLVENCGISKDDPYVPNIFGGAKTNIQENPWMVLVW 60
            :|||:      ||     .|:|       .:.::||..|..  |..|.||..|::...||.|.:.
Human   132 LEVIS------VCDCPRGRFLA-------AICQDCGRRKLP--VDRIVGGRDTSLGRWPWQVSLR 181

  Fly    61 --SSKPCGGSLIARQFVLTAAHCVSFEDLYV---RLGDYETLDPMPYCLNNHCIPKFYNISVDMK 120
              .:..|||||::..:|||||||....:..:   |:.........|:.|         .:.|...
Human   182 YDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGAVAQASPHGL---------QLGVQAV 237

  Fly   121 IVHENY------NGITLQNDIALLRMSEAVEYSDYVRPICL-LVGEQMQSIPMFTVTGWGETE-Y 177
            :.|..|      |.....|||||:.:|..:..::|::|:|| ..|:.:....:.||||||.|: |
Human   238 VYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQYY 302

  Fly   178 GQFSRILLNATLYNMDISYCNIK--FNKQADRSQICAGSHTS--NTCKGDSGGPLSSKFHYGN-- 236
            ||.:.:|..|.:..:....||..  :..|......|||....  :.|:||||||...:.....
Human   303 GQQAGVLQEARVPIISNDVCNGADFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTP 367

  Fly   237 --RLLSFQYGLVSYGSERCAANVAGVYTNVSYHREWIF 272
              ||.    |:||:|:....|...||||.||..|||||
Human   368 RWRLC----GIVSWGTGCALAQKPGVYTKVSDFREWIF 401

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30289	NP_726081.1	Tryp_SPc	42..271	CDD:238113	77/249 (31%)
HPN	NP_002142.1	Hepsin-SRCR	51..159	CDD:462736	10/39 (26%)
		Tryp_SPc	163..400	CDD:238113	77/249 (31%)