Protein Alignment CG30289 and HGF

DIOPT Version :10

• Sequence 1: NP_726081.1
• Gene: CG30289 / 246532
• FlyBaseID: FBgn0050289
• Length: 316
• Species: Drosophila melanogaster
• Sequence 2: NP_000592.3
• Gene: HGF / 3082
• HGNCID: 4893
• Length: 728
• Species: Homo sapiens
• Alignment Length: 280
• Identity: 79/280 - (28%)
• Similarity: 119/280 - (42%)
• Gaps: 66/280 - (23%)

  Fly    27 VENCGISKDDPYVPNIFGGAKTNIQENPWMV-LVWSSKP-CGGSLIARQFVLTAAHCVSFEDLYV 89
            |.:|..:|....|..|  ..:|||   .||| |.:.:|. ||||||...:||||..|....|
Human   484 VISCAKTKQLRVVNGI--PTRTNI---GWMVSLRYRNKHICGGSLIKESWVLTARQCFPSRD--- 540

  Fly    90 RLGDYETLDPMPYCLNNHCI--------PKFYNISVDMKIVHENYNGITLQNDIALLRMSEAVEY 146
             |.|||.      .|..|.:        .:..|:|   ::|:....     :|:.|::::.....
Human   541 -LKDYEA------WLGIHDVHGRGDEKCKQVLNVS---QLVYGPEG-----SDLVLMKLARPAVL 590

  Fly   147 SDYVRPI------CLLVGEQMQSIPMFT---VTGWGETEYGQFSRILLNATLYNMDISYCN---- 198
            .|:|..|      |        :||..|   |.|||.|....:..:|..|.||.|....|:
Human   591 DDFVSTIDLPNYGC--------TIPEKTSCSVYGWGYTGLINYDGLLRVAHLYIMGNEKCSQHHR 647

  Fly   199 --IKFNKQADRSQICAGSHT--SNTCKGDSGGPLSSKFHYGNRLLSFQYGLVSYGSERCAANVAG 259
              :..|:    |:||||:..  |..|:||.||||..:.|....:|    |::..|......|..|
Human   648 GKVTLNE----SEICAGAEKIGSGPCEGDYGGPLVCEQHKMRMVL----GVIVPGRGCAIPNRPG 704

  Fly   260 VYTNVSYHREWIFNKMVQFK 279
            ::..|:|:.:||...::.:|
Human   705 IFVRVAYYAKWIHKIILTYK 724

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30289	NP_726081.1	Tryp_SPc	42..271	CDD:238113	72/255 (28%)
HGF	NP_000592.3	PAN_APPLE	39..122	CDD:238074
		KR	126..208	CDD:214527
		KR	210..290	CDD:214527
		KR	304..384	CDD:214527
		KR	388..470	CDD:238056
		Tryp_SPc	494..716	CDD:214473	73/260 (28%)