Protein Alignment CG30289 and Ctsg

DIOPT Version :10

• Sequence 1: NP_726081.1
• Gene: CG30289 / 246532
• FlyBaseID: FBgn0050289
• Length: 316
• Species: Drosophila melanogaster
• Sequence 2: NP_031826.1
• Gene: Ctsg / 13035
• MGIID: 88563
• Length: 261
• Species: Mus musculus
• Alignment Length: 253
• Identity: 74/253 - (29%)
• Similarity: 108/253 - (42%)
• Gaps: 40/253 - (15%)

  Fly    42 IFGGAKTNIQENPWMVLVWSSKP-----CGGSLIARQFVLTAAHCVSFEDLYVRLGDY-----ET 96
            |.||.:......|:|..:....|     |||.|:...||||||||:. ..:.|.||.:     |.
Mouse    21 IIGGREARPHSYPYMAFLLIQSPEGLSACGGFLVREDFVLTAAHCLG-SSINVTLGAHNIQMRER 84

  Fly    97 LDPMPYCLNNHCIPKFYNISVDMKIVHENYNGITLQNDIALLRMSEAVEYSDYVRPICL-LVGEQ 160
            ...:              |:|...|.|.:||...::|||.||::......|..|:|:.| ...::
Mouse    85 TQQL--------------ITVLRAIRHPDYNPQNIRNDIMLLQLRRRARRSGSVKPVALPQASKK 135

  Fly   161 MQSIPMFTVTGWGETEYGQFSRILLNATL-YNMDISYCNIKFNKQADRSQICAGS--HTSNTCKG 222
            :|...:.||.|||.....:.:.:|....| ..|| ..|..:|.....::|||.|:  ...:..:|
Mouse   136 LQPGDLCTVAGWGRVSQSRGTNVLQEVQLRVQMD-QMCANRFQFYNSQTQICVGNPRERKSAFRG 199

  Fly   223 DSGGPLSSKFHYGNRLLSFQYGLVSYGSERCAANVAGVYTNVSYHREWIFNKMVQFKP 280
            ||||||...        :...|:|||||..  .|...|:|.:.....||...|.:|.|
Mouse   200 DSGGPLVCS--------NVAQGIVSYGSNN--GNPPAVFTKIQSFMPWIKRTMRRFAP 247

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30289	NP_726081.1	Tryp_SPc	42..271	CDD:238113	69/242 (29%)
Ctsg	NP_031826.1	Tryp_SPc	21..241	CDD:238113	71/245 (29%)
		Important for antimicrobial activity. /evidence=ECO:0000250|UniProtKB:P08311	21..25		2/3 (67%)
		Important for antimicrobial activity. /evidence=ECO:0000250|UniProtKB:P08311	97..111		6/13 (46%)