DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30287 and c1s

DIOPT Version :9

Sequence 1:	NP_726083.1	Gene:	CG30287 / 246530	FlyBaseID:	FBgn0050287	Length:	284	Species:	Drosophila melanogaster
Sequence 2:	XP_002941253.2	Gene:	c1s / 613055	XenbaseID:	XB-GENE-995410	Length:	691	Species:	Xenopus tropicalis

Alignment Length:	275	Identity:	80/275 - (29%)
Similarity:	121/275 - (44%)	Gaps:	52/275 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 PQCVTARSEPGLYRVINGKPADLFSNPWMVII--IERGMMKCGGSLITPRYVLTAAHCKSETKSQ 90
            |.|...:|:.. .|:..|..|.....|||:..  ||.|    |||||:.|:||||||.
Frog   424 PVCGVHQSDKS-GRIFGGTRAKPGQFPWMIQFTDIELG----GGSLISDRWVLTAAHV------- 476

  Fly    91 LTVRLGDYDVNQAVDCSSYGCIPR---------------PREINVTRTYVPSHYT----NFRKND 136
                     ||:.:..:.:|.:.:               .::|.:...|..:..|    || .||
Frog   477 ---------VNKKIFPTMFGGVMKFFPNTNLQSQEKRLQAKKIIIHPLYQDNEDTEGQSNF-DND 531

  Fly   137 IALLRLETTVQYGDNIRSICLLMGDYTWSSNILKNLVKFNTTGWGRTESRINSPVLQQASLTHHH 201
            |||::|...|:.|..|..|||.........|.:..:     .|||:||.|.::..||.||::...
Frog   532 IALVQLTKKVKLGSCISPICLPRRGLAPVVNEVATI-----AGWGKTEKRESAVNLQFASISLSS 591

  Fly   202 LSYCAQVFGKQ--LDKSHICVASSTG-STCQGDSGGPLTARVRIGSERRVILFGVVSYGAVHCFG 263
            :..|.:..|.:  ...:.:|..|..| .:|.|||||||.......|. ::.:.|:||:|...|..
Frog   592 MDKCKKATGGKGYFTPNMLCAGSDVGKDSCNGDSGGPLMFTDPQDSS-KMYMAGIVSWGPRDCGT 655

  Fly   264 PTVYTNVIHFANWIE 278
            ..:||.|.::.:|||
Frog   656 YGLYTKVDNYLDWIE 670

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30287	NP_726083.1	Tryp_SPc	41..277	CDD:214473	74/259 (29%)
CG30287	NP_726083.1	Tryp_SPc	42..280	CDD:238113	76/261 (29%)
c1s	XP_002941253.2	CUB	21..131	CDD:238001
		FXa_inhibition	145..173	CDD:405372
		CUB	177..288	CDD:238001
		PHA02927	301..>436	CDD:222943	3/12 (25%)
		Tryp_SPc	436..669	CDD:214473	74/259 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910