DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30287 and Hgfac

DIOPT Version :9

Sequence 1:	NP_726083.1	Gene:	CG30287 / 246530	FlyBaseID:	FBgn0050287	Length:	284	Species:	Drosophila melanogaster
Sequence 2:	NP_445772.1	Gene:	Hgfac / 58947	RGDID:	70909	Length:	653	Species:	Rattus norvegicus

Alignment Length:	262	Identity:	74/262 - (28%)
Similarity:	113/262 - (43%)	Gaps:	52/262 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 RVINGKPADLFSNPWM-VIIIERGMMKCGGSLITPRYVLTAAHC--KSETKSQLTVRLGDYDVNQ 102
            |:|.|..:...|:||: .|.|..|.  |.|||:...:|::||||  .|..:..:||.||.:..|:
  Rat   405 RIIGGSSSLPGSHPWLAAIYIGNGF--CAGSLVHTCWVVSAAHCFSSSPPRDSITVVLGQHFFNR 467

  Fly   103 AVDCSSYGCIPRPREINVTRT-----YVP-SHYTNFRKN--DIALLRL----ETTVQYGDNIRSI 155
            ..|              ||:|     ||| :.|:.|..|  |:.|:||    |........::.|
  Rat   468 TTD--------------VTQTFAIEKYVPYTLYSVFNPNDHDLVLIRLKKKGERCAVRSQFVQPI 518

  Fly   156 CLLMGDYTWSSNILKNLVKFNTTGWGRTESRI----NSPVLQQASLTHHHLSYCAQVFGKQLDKS 216
            ||.....::.:.     .|....|||..:..:    ||.:.....|...|.....:|:|..:..:
  Rat   519 CLPEAGSSFPTG-----HKCQIAGWGHMDENVSGYSNSLLEALVPLVADHKCSSPEVYGADISPN 578

  Fly   217 HICVA--SSTGSTCQGDSGGPLTARVRIGSERRVI--LFGVVSY--GAVHCFGPTVYTNVIHFAN 275
            .:|..  ......|||||||||..      |:..:  |:|::|:  |......|.|||.|.::.:
  Rat   579 MLCAGYFDCKSDACQGDSGGPLVC------EKNGVAYLYGIISWGDGCGRLNKPGVYTRVSNYVD 637

  Fly   276 WI 277
            ||
  Rat   638 WI 639

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30287	NP_726083.1	Tryp_SPc	41..277	CDD:214473	72/260 (28%)
CG30287	NP_726083.1	Tryp_SPc	42..280	CDD:238113	73/261 (28%)
Hgfac	NP_445772.1	FN2	99..145	CDD:128373
		EGF_CA	159..194	CDD:238011
		FN1	197..237	CDD:238018
		EGF	242..274	CDD:278437
		Kringle	283..364	CDD:278480
		Tryp_SPc	405..639	CDD:214473	72/260 (28%)
		Tryp_SPc	406..641	CDD:238113	73/261 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910