Protein Alignment CG30287 and KLK6

DIOPT Version :10

• Sequence 1: NP_726083.1
• Gene: CG30287 / 246530
• FlyBaseID: FBgn0050287
• Length: 284
• Species: Drosophila melanogaster
• Sequence 2: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Alignment Length: 247
• Identity: 74/247 - (29%)
• Similarity: 110/247 - (44%)
• Gaps: 38/247 - (15%)

  Fly    41 RVINGKPADLFSNPWMVIIIERGMMKCGGSLITPRYVLTAAHCKSETKSQLTVRLGDYDVNQAVD 105
            ::::|.|.|..|:|:...:...|.:.|||.||.|.:||||||||   |..|.|.||.:::.|...
Human    21 KLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCK---KPNLQVFLGKHNLRQRES 82

  Fly   106 CSSYGCIPRPREINVTRTYV-PSHYTNFRKNDIALLRLETTVQYGDNIRSICLLMGDYTWSSNIL 169
            ..        .:.:|.|..: |.:.......||.||||....:..:.|:.:.|       ..:..
Human    83 SQ--------EQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQPLPL-------ERDCS 132

  Fly   170 KNLVKFNTTGWGRTESRINSPVLQQASLTHHHL---SYCAQVFGKQLDKSHICVASST--GSTCQ 229
            .|....:..|||:|........:|.|.:   ||   ..|...:..|:.::.:|.....  ..:||
Human   133 ANTTSCHILGWGKTADGDFPDTIQCAYI---HLVSREECEHAYPGQITQNMLCAGDEKYGKDSCQ 194

  Fly   230 GDSGGPLTARVRIGSERRVILFGVVSYGAVHCFG---PTVYTNVIHFANWIE 278
            |||||||..    |...|    |:||:|.:.|..   |.|||||..:.|||:
Human   195 GDSGGPLVC----GDHLR----GLVSWGNIPCGSKEKPGVYTNVCRYTNWIQ 238

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30287	NP_726083.1	Tryp_SPc	42..280	CDD:238113	74/246 (30%)
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	72/242 (30%)