Protein Alignment CG30287 and KLK15

DIOPT Version :10

• Sequence 1: NP_726083.1
• Gene: CG30287 / 246530
• FlyBaseID: FBgn0050287
• Length: 284
• Species: Drosophila melanogaster
• Sequence 2: NP_059979.2
• Gene: KLK15 / 55554
• HGNCID: 20453
• Length: 256
• Species: Homo sapiens
• Alignment Length: 301
• Identity: 89/301 - (29%)
• Similarity: 132/301 - (43%)
• Gaps: 73/301 - (24%)

  Fly    10 LLIALVFLKVQGQPHLLDPQCVTARSEPGLYRVINGKPADLFSNPWMVIIIERGMMKCGGSLITP 74
            ||:.|.||...           ||..:..  :::.|......|.||.|.:.|||...||.|||:|
Human     3 LLLTLSFLLAS-----------TAAQDGD--KLLEGDECAPHSQPWQVALYERGRFNCGASLISP 54

  Fly    75 RYVLTAAHCKSETKSQLTVRLGDYDVNQAVDCSSYGCIPRPREINVTRTYVP-------SHYTNF 132
            .:||:||||:|..   :.||||::::.:.         ..|.::..|...:|       ||
Human    55 HWVLSAAHCQSRF---MRVRLGEHNLRKR---------DGPEQLRTTSRVIPHPRYEARSH---- 103

  Fly   133 RKNDIALLRLETTVQYGDNIR------------SICLLMGDYTWSSNILKNLVKFNTTGW-GRTE 184
             :|||.||||....:....:|            ..|::.|   |      .||..|..|. |...
Human   104 -RNDIMLLRLVQPARLNPQVRPAVLPTRCPHPGEACVVSG---W------GLVSHNEPGTAGSPR 158

  Fly   185 SRINSP-VLQQASLTHHHLSYCAQVFGKQLDKSHICV-ASSTGS-TCQGDSGGPLTARVRIGSER 246
            |:::.| .|..|:::....:.|.:.:..:|..:.:|. |...|: :|:|||||||..    |.
Human   159 SQVSLPDTLHCANISIISDTSCDKSYPGRLTNTMVCAGAEGRGAESCEGDSGGPLVC----GG-- 217

  Fly   247 RVILFGVVSYGAVHCFG---PTVYTNVIHFANWIELHTKKN 284
              ||.|:||:|.|.|..   |.|||.|.|:..||....|:|
Human   218 --ILQGIVSWGDVPCDNTTKPGVYTKVCHYLEWIRETMKRN 256

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30287	NP_726083.1	Tryp_SPc	42..280	CDD:238113	80/263 (30%)
KLK15	NP_059979.2	Tryp_SPc	25..249	CDD:214473	78/257 (30%)