DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30287 and hgfa

DIOPT Version :9

Sequence 1:	NP_726083.1	Gene:	CG30287 / 246530	FlyBaseID:	FBgn0050287	Length:	284	Species:	Drosophila melanogaster
Sequence 2:	XP_005164799.1	Gene:	hgfa / 493781	ZFINID:	ZDB-GENE-041014-2	Length:	712	Species:	Danio rerio

Alignment Length:	280	Identity:	63/280 - (22%)
Similarity:	106/280 - (37%)	Gaps:	61/280 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 KVQGQPHLLDPQCVTARSEPGLYRVINGKPADLFSNPWMVIIIERGMMK-CGGSLITPRYVLTAA 81
            ::.|.|   .|.|...::.    |::.|.......:...|:.|::|... ||||||...:|||..
Zfish   460 QMSGGP---KPSCFIHKTT----RIVGGMRVQRAEDGSWVVSIQKGNRHWCGGSLIREEWVLTDQ 517

  Fly    82 HCKS---ETKSQLTVRLGDYDVN-----QAVDCSSYGCIPRPREINVTRTYVPSHYTNFRKNDIA 138
            .|.|   ...|:.||::|...:|     ||:..:...|.|                   ..:::|
Zfish   518 QCFSTCVPDLSEYTVQVGLLHLNASAGTQALRIAHVVCGP-------------------EGSNLA 563

  Fly   139 LLRLETTVQYGDNIRSICLLMGDYTWSSNILKNLVKFNTTGWGRTESRINSPVLQQASLTHHHLS 203
            ||:|.|.....:::|::.|.:.....:...|..:.     |||.|:...:...|:...|
Zfish   564 LLKLTTPAPLSEHVRTVQLPVAGCAVAEGTLCLMY-----GWGDTKGTGHEGSLKMVGL------ 617

  Fly   204 YCAQVFGKQLDKSH----------ICVASSTG-STCQGDSGGPLTARVRIGSERRVILFGVVSYG 257
              ..|..|:..:||          ||...... ..|:.|.||||..:.  |..:.::...:...|
Zfish   618 --PIVSNKRCSQSHNGILPITETKICAGGKRDQGVCEKDYGGPLVCQE--GESKVIVGVSINGRG 678

  Fly   258 AVHCFGPTVYTNVIHFANWI 277
            ......|.|:.||..::.||
Zfish   679 CAVARRPAVFVNVAFYSEWI 698

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30287	NP_726083.1	Tryp_SPc	41..277	CDD:214473	57/255 (22%)
CG30287	NP_726083.1	Tryp_SPc	42..280	CDD:238113	58/256 (23%)
hgfa	XP_005164799.1	PAN_AP_HGF	<50..107	CDD:238532
		KR	111..192	CDD:238056
		KR	195..275	CDD:214527
		KR	287..367	CDD:214527
		KR	374..451	CDD:214527
		Tryp_SPc	476..698	CDD:214473	57/255 (22%)
		Tryp_SPc	477..701	CDD:238113	58/256 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575858
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930