DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG30287 and KLK2

DIOPT Version :9

Sequence 1:NP_726083.1 Gene:CG30287 / 246530 FlyBaseID:FBgn0050287 Length:284 Species:Drosophila melanogaster
Sequence 2:NP_005542.1 Gene:KLK2 / 3817 HGNCID:6363 Length:261 Species:Homo sapiens


Alignment Length:262 Identity:78/262 - (29%)
Similarity:115/262 - (43%) Gaps:55/262 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly    41 RVINGKPADLFSNPWMVIIIERGMMKCGGSLITPRYVLTAAHCKSETKSQLTVRLGDY------D 99
            |::.|...:..|.||.|.:...|...|||.|:.|::|||||||   .|....|.||.:      |
Human    24 RIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHC---LKKNSQVWLGRHNLFEPED 85

  Fly   100 VNQAVDCSSYGCIPRPREINVT----RTYVPSHYTNFRKNDIALLRLETTVQYGDNIRSICL--- 157
            ..|.|..|.  ..|.|. .|::    ::..|...::   :|:.||||....:..|.::.:.|   
Human    86 TGQRVPVSH--SFPHPL-YNMSLLKHQSLRPDEDSS---HDLMLLRLSEPAKITDVVKVLGLPTQ 144

  Fly   158 --LMGDYTWSSNILKNLVKFNTTGWGRTESR--INSPVLQQASLTHHHLS--YCAQVFGKQLDKS 216
              .:|...::|            |||..|..  :....||..||  |.||  .||:.:.:::.:.
Human   145 EPALGTTCYAS------------GWGSIEPEEFLRPRSLQCVSL--HLLSNDMCARAYSEKVTEF 195

  Fly   217 HICVASSTG--STCQGDSGGPLTARVRIGSERRVILFGVVSYGAVHCF---GPTVYTNVIHFANW 276
            .:|....||  .||.|||||||..        ..:|.|:.|:|...|.   .|.|||.|:|:..|
Human   196 MLCAGLWTGGKDTCGGDSGGPLVC--------NGVLQGITSWGPEPCALPEKPAVYTKVVHYRKW 252

  Fly   277 IE 278
            |:
Human   253 IK 254

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG30287NP_726083.1 Tryp_SPc 41..277 CDD:214473 76/259 (29%)
Tryp_SPc 42..280 CDD:238113 77/261 (30%)
KLK2NP_005542.1 Tryp_SPc 25..256 CDD:238113 77/261 (30%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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