DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30287 and Lrp8

DIOPT Version :9

Sequence 1:	NP_726083.1	Gene:	CG30287 / 246530	FlyBaseID:	FBgn0050287	Length:	284	Species:	Drosophila melanogaster
Sequence 2:	XP_006238632.1	Gene:	Lrp8 / 362558	RGDID:	1305729	Length:	1013	Species:	Rattus norvegicus

Alignment Length:	117	Identity:	27/117 - (23%)
Similarity:	41/117 - (35%)	Gaps:	30/117 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   152 IRSICLLMGDYTWSSNILKNLVKF------NTTGW-GRTESRINSPVLQQASLTHHHLSYCAQVF 209
            :|.|.|:..||:....:|||:|..      |...| ..:..:|.|..:.:||:....:    .:.
  Rat   482 VRRIDLVKRDYSRLIPMLKNVVALDVEVDTNRIYWCDLSYRKIYSAHMDKASIPDEQV----VLI 542

  Fly   210 GKQLDK----------SHICVASSTGSTCQGDSGGPLTARVRIGSERRVILF 251
            |:||..          .||...         |||....:.......||..||
  Rat   543 GEQLHSPEGLAVDWVHKHIYWT---------DSGNKTVSVATTDGRRRCTLF 585

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30287	NP_726083.1	Tryp_SPc	41..277	CDD:214473	27/117 (23%)
CG30287	NP_726083.1	Tryp_SPc	42..280	CDD:238113	27/117 (23%)
Lrp8	XP_006238632.1	LDLa	44..78	CDD:238060
		LDLa	82..114	CDD:197566
		LDLa	124..160	CDD:238060
		LDLa	203..235	CDD:197566
		LDLa	256..289	CDD:238060
		LDLa	295..329	CDD:238060
		LDLa	333..369	CDD:294076
		FXa_inhibition	390..424	CDD:291342
		EGF_CA	426..456	CDD:214542
		LY	495..530	CDD:214531	8/34 (24%)
		LY	540..581	CDD:214531	8/49 (16%)
		Ldl_recept_b	602..642	CDD:278487
		LY	626..668	CDD:214531
		Ldl_recept_b	689..728	CDD:278487
		FXa_inhibition	747..784	CDD:291342
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910