DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30287 and AgaP_AGAP005304

DIOPT Version :9

Sequence 1:	NP_726083.1	Gene:	CG30287 / 246530	FlyBaseID:	FBgn0050287	Length:	284	Species:	Drosophila melanogaster
Sequence 2:	XP_560320.2	Gene:	AgaP_AGAP005304 / 3289940	VectorBaseID:	AGAP005304	Length:	501	Species:	Anopheles gambiae

Alignment Length:	267	Identity:	61/267 - (22%)
Similarity:	95/267 - (35%)	Gaps:	61/267 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 GKPADLFSNPWMVIIIERGMMKCGG----SLITPRYVLTAAHCKSETKSQLTVRLGDYDVNQAVD 105
            |:.:..:..||...:....:...||    :||...|.:..|.|...:.:|..:..|.:.....::
Mosquito   239 GESSPSYLTPWTGGVYYDKLEFEGGTGLVTLINEWYAVGPASCFDNSSAQFIIVFGFFGKAIEIE 303

  Fly   106 CSSYG----CIPRPREINVTRTYVPSHYTNFRKNDIALLRLETTVQYG-DNIRSICLLMGDYTWS 165
            |....    |...|:.:.|.:.:....|...|.:||||::|.|.|... .|::.|||.:.|...|
Mosquito   304 CDMTNNTELCNVPPQSVTVQKVFNHPLYNGTRNHDIALVKLATRVDTSRPNVKPICLPITDAIRS 368

  Fly   166 ---SNILKNLVKFNTT--------------GWGRTESRINSPVLQQASLTHHHLSYCAQVFGKQL 213
               ||::.....|..|              .|...:.|.                        .:
Mosquito   369 YDVSNLVMRKSSFELTKVDDRYVDTEECQKRWQGLKVRF------------------------AV 409

  Fly   214 DKSHICVAS--STGSTC----QGDSGGPLTARVRIGSERRVILFGVVSYGAVHC--FGPTVYTNV 270
            |:|..||..  :...||    .|||   |.:...:.|..|..|.|.|.....||  :.|.||||.
Mosquito   410 DESKHCVIQQRTMEETCITINAGDS---LQSLQTMASGDRHFLRGFVIARPSHCSIYYPVVYTNT 471

  Fly   271 IHFANWI 277
            ..:.:||
Mosquito   472 DTYLDWI 478

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30287	NP_726083.1	Tryp_SPc	41..277	CDD:214473	59/265 (22%)
CG30287	NP_726083.1	Tryp_SPc	42..280	CDD:238113	61/267 (23%)
AgaP_AGAP005304	XP_560320.2	Tryp_SPc	<12..>76	CDD:304450
		Tryp_SPc	248..481	CDD:304450	60/258 (23%)
		Tryp_SPc	248..478	CDD:214473	58/256 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910