DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30287 and HABP2

DIOPT Version :9

Sequence 1:	NP_726083.1	Gene:	CG30287 / 246530	FlyBaseID:	FBgn0050287	Length:	284	Species:	Drosophila melanogaster
Sequence 2:	NP_004123.1	Gene:	HABP2 / 3026	HGNCID:	4798	Length:	560	Species:	Homo sapiens

Alignment Length:	272	Identity:	83/272 - (30%)
Similarity:	121/272 - (44%)	Gaps:	41/272 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 TARSEPGLYRVINGKPADLFSNPW---------MVIIIERGMMKCGGSLITPRYVLTAAHCKSET 87
            |..:|..:.|:..|..:....:||         :.|.:.:|.. |||:||.|.:|||||||....
Human   304 TEIAERKIKRIYGGFKSTAGKHPWQASLQSSLPLTISMPQGHF-CGGALIHPCWVLTAAHCTDIK 367

  Fly    88 KSQLTVRLGDYDVNQAVDCSSYGCIPRPREINVTRTYVPSHYT---NFRKNDIALLRLETTVQY- 148
            ...|.|.|||.|:.:...        ..:...|.:.:..|||.   ....||||||:|:....:
Human   368 TRHLKVVLGDQDLKKEEF--------HEQSFRVEKIFKYSHYNERDEIPHNDIALLKLKPVDGHC 424

  Fly   149 ---GDNIRSICLLMGDYTWSSNILKNLVKFNTTGWGRTESRINSPVLQQA--SLTHHHLSYCAQV 208
               ...::::||..|.:...|       :.:.:|||.||:...|..|..|  .|..:.|....|:
Human   425 ALESKYVKTVCLPDGSFPSGS-------ECHISGWGVTETGKGSRQLLDAKVKLIANTLCNSRQL 482

  Fly   209 FGKQLDKSHICVAS--STG-STCQGDSGGPLTARVRIGSERRVILFGVVSYGAVHCFGPTVYTNV 270
            :...:|.|.||..:  ..| .|||||||||||..    .:....::|:||:|......|.|||.|
Human   483 YDHMIDDSMICAGNLQKPGQDTCQGDSGGPLTCE----KDGTYYVYGIVSWGLECGKRPGVYTQV 543

  Fly   271 IHFANWIELHTK 282
            ..|.|||:...|
Human   544 TKFLNWIKATIK 555

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30287	NP_726083.1	Tryp_SPc	41..277	CDD:214473	78/256 (30%)
CG30287	NP_726083.1	Tryp_SPc	42..280	CDD:238113	79/258 (31%)
HABP2	NP_004123.1	EGF	77..106	CDD:306513
		KR	191..277	CDD:238056
		Tryp_SPc	314..553	CDD:238113	79/258 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143043
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840