DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30287 and Habp2

DIOPT Version :9

Sequence 1:	NP_726083.1	Gene:	CG30287 / 246530	FlyBaseID:	FBgn0050287	Length:	284	Species:	Drosophila melanogaster
Sequence 2:	NP_001001505.2	Gene:	Habp2 / 292126	RGDID:	1302979	Length:	558	Species:	Rattus norvegicus

Alignment Length:	281	Identity:	83/281 - (29%)
Similarity:	119/281 - (42%)	Gaps:	67/281 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 TARSEPGLYRVINGKPADLFSNPWMVII-----IERGMMK---CGGSLITPRYVLTAAHCKSETK 88
            |..:|..:.|:..|..:....:||.|.:     :...|.:   ||||||.|.:|||||||...:.
  Rat   302 TEMTEHAVKRIYGGFKSTAGKHPWQVSLQTSLPLTTSMPQGHFCGGSLIHPCWVLTAAHCTDMST 366

  Fly    89 SQLTVRLGDYDVNQAVDCSSYGCIPRPREINVTRTYVPSHYTNFR-----------------KND 136
            ..|.|.|||.|:.:                      ..||...||                 .||
  Rat   367 KHLKVVLGDQDLKK----------------------TESHEQTFRVEKILKYSQYNERDEIPHND 409

  Fly   137 IALLRLETTVQY----GDNIRSICLLMGDYTWSSNILKNLVKFNTTGWGRTESRINSPVLQQA-- 195
            ||||:|:....:    ...::::||       .|:...:..:.:.:|||.||:...|..|..|
  Rat   410 IALLKLKPVGGHCALESKYVKTVCL-------PSDPFPSGTECHISGWGVTETGEGSRQLLDAKV 467

  Fly   196 SLTHHHLSYCAQVFGKQLDKSHICVAS--STGS-TCQGDSGGPLTARVRIGSERRVILFGVVSYG 257
            .|..:.|....|::...:|.|.||..:  ..|| |||||||||||..    .:....::|:||:|
  Rat   468 KLIANALCNSRQLYDHTIDDSMICAGNLQKPGSDTCQGDSGGPLTCE----KDGTYYVYGIVSWG 528

  Fly   258 AVHCFGPTVYTNVIHFANWIE 278
            ......|.|||.|..|.|||:
  Rat   529 QECGKKPGVYTQVTKFLNWIK 549

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30287	NP_726083.1	Tryp_SPc	41..277	CDD:214473	79/269 (29%)
CG30287	NP_726083.1	Tryp_SPc	42..280	CDD:238113	80/271 (30%)
Habp2	NP_001001505.2	EGF_CA	71..107	CDD:238011
		KR	191..275	CDD:238056
		Tryp_SPc	312..551	CDD:238113	80/271 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166336754
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840