Protein Alignment CG30287 and KLK13

DIOPT Version :10

• Sequence 1: NP_726083.1
• Gene: CG30287 / 246530
• FlyBaseID: FBgn0050287
• Length: 284
• Species: Drosophila melanogaster
• Sequence 2: NP_056411.1
• Gene: KLK13 / 26085
• HGNCID: 6361
• Length: 277
• Species: Homo sapiens
• Alignment Length: 302
• Identity: 88/302 - (29%)
• Similarity: 131/302 - (43%)
• Gaps: 67/302 - (22%)

  Fly     8 LLLLIALVFLKVQGQPHLLDPQCVTARSEPGLYRVINGKPADLF----------SNPWMVIIIER 62
            |.|:||.:.|.:.|.        |:..|.    :|:|......|          |.||...::.:
Human     4 LALVIASLTLALSGG--------VSQESS----KVLNTNGTSGFLPGGYTCFPHSQPWQAALLVQ 56

  Fly    63 GMMKCGGSLITPRYVLTAAHCKSETKSQLTVRLGDY---------DVNQAVDCSSYGCIPRPREI 118
            |.:.|||.|:.|::|||||||   .|..|.|.||.:         .|.:.|.     .||.|
Human    57 GRLLCGGVLVHPKWVLTAAHC---LKEGLKVYLGKHALGRVEAGEQVREVVH-----SIPHP--- 110

  Fly   119 NVTRTYVPSHYTNFRKNDIALLRLETTVQYGDNIRSICLLMGDYTWSSNILKNLVKFNTTGWGRT 183
            ...|:  |:|..:  .:||.||.|::.||....|:::.|.      .:|.|........:|||.|
Human   111 EYRRS--PTHLNH--DHDIMLLELQSPVQLTGYIQTLPLS------HNNRLTPGTTCRVSGWGTT 165

  Fly   184 ES-RINSP-VLQQASLTHHHLSYCAQVFGKQLDKSHICVASSTG--STCQGDSGGPLTARVRIGS 244
            .| ::|.| .||.|::.......|.||:..::..:.:|..:..|  .:|:|||||||..
Human   166 TSPQVNYPKTLQCANIQLRSDEECRQVYPGKITDNMLCAGTKEGGKDSCEGDSGGPLVC------ 224

  Fly   245 ERRVILFGVVSYGAVHCFGPT---VYTNVIHFANWIELHTKK 283
              ...|:|:||:|...|..|.   |||.|..:..||....:|
Human   225 --NRTLYGIVSWGDFPCGQPDRPGVYTRVSRYVLWIRETIRK 264

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30287	NP_726083.1	Tryp_SPc	42..280	CDD:238113	79/263 (30%)
KLK13	NP_056411.1	Tryp_SPc	38..261	CDD:238113	76/251 (30%)