DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30287 and mst1

DIOPT Version :9

Sequence 1:	NP_726083.1	Gene:	CG30287 / 246530	FlyBaseID:	FBgn0050287	Length:	284	Species:	Drosophila melanogaster
Sequence 2:	NP_694512.1	Gene:	mst1 / 259260	ZFINID:	ZDB-GENE-020806-3	Length:	709	Species:	Danio rerio

Alignment Length:	250	Identity:	59/250 - (23%)
Similarity:	106/250 - (42%)	Gaps:	39/250 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 RVINGKPADLFSNPWMVIIIER-GMMKCGGSLITPRYVLTAAHCKSETKSQLTVRLGDYDVNQAV 104
            |::.|.|.   ::||.|.:.:| |...|||||::..:|::...|.|..               .|
Zfish   481 RIVGGTPG---NSPWTVSLRDRKGNHFCGGSLVSSEWVISTKQCFSSC---------------YV 527

  Fly   105 DCSSYGCI-------PRPREINVTRTYVPSHYTNFRKNDIALLRLETTVQYGDNIRSICLLMGDY 162
            |.:.|..:       |:..|.::.|..:........::.:.:|:|||..|:.:.:..|||....|
Zfish   528 DLTGYTAMMGTLFRDPKEGEPDLQRISLTKIVCGPSESHLVMLQLETPAQFNERVSQICLPPERY 592

  Fly   163 TWSSNILKNLVKFNTTGWGRTESRINSPVLQQASLTHHHLSYCAQVFGKQLDKSHIC-VASSTG- 225
                 |:.:.......|||.|:.:.:..||..|.:.......|.|.|..::.::.:| :|...|
Zfish   593 -----IVPDGTICEIAGWGETKGKGDETVLNVAQMPVLSNKDCNQYFKGRVRENEMCTMAFQAGV 652

  Fly   226 STCQGDSGGPLTARVRIGSERRVILFGVV--SYGAVHCFGPTVYTNVIHFANWIE 278
            ..|:.|.||||..:    :....:|.||:  .....|...|.::..|..:.:||:
Zfish   653 GACERDYGGPLACQ----NSDCWVLEGVIIPMRRCGHAGQPNIFIRVSVYVDWIK 703

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30287	NP_726083.1	Tryp_SPc	41..277	CDD:214473	57/247 (23%)
CG30287	NP_726083.1	Tryp_SPc	42..280	CDD:238113	58/248 (23%)
mst1	NP_694512.1	PAN_AP_HGF	24..105	CDD:238532
		KR	109..187	CDD:238056
		KR	192..271	CDD:214527
		KR	284..365	CDD:214527
		KR	370..451	CDD:238056
		Tryp_SPc	481..702	CDD:214473	57/247 (23%)
		Tryp_SPc	482..705	CDD:238113	58/248 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575871
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930